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Nicotine dependence – human and animal studies, current pharmacotherapies and future perspectives

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The positive allosteric modulator of the GABAB receptor, rac-BHFF, suppresses alcohol self-administration

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Smoking Cessation Intervention: An Evidence-Based Approach

(2010) Rafael Laniado-Laborín   POSTGRADUATE MEDICINE

Varenicline’s effects on acute smoking behavior and reward and their association with subsequent abstinence

(2010) Kenneth A. Perkins et al.   PSYCHOPHARMACOLOGY

Mechanism-based medication development for the treatment of nicotine dependence

(2009) Zheng-xiong Xi et al.   ACTA PHARMACOLOGICA SINICA

Reduction of Alcohol’s Reinforcing and Motivational Properties by the Positive Allosteric Modulator of the GABABReceptor, BHF177, in Alcohol-Preferring Rats

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The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study

(2009) Teresa R. Franklin et al.   DRUG AND ALCOHOL DEPENDENCE

Baclofen prevents drug-induced reinstatement of extinguished nicotine-seeking behaviour and nicotine place preference in rodents

(2009) Liana Fattore et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Relationship Between the Hypothalamic-Pituitary-Thyroid Axis and Alcohol Craving in Alcohol-Dependent Patients: A Longitudinal Study

(2008) Lorenzo Leggio et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Specific Reduction of Alcohol’s Motivational Properties by the Positive Allosteric Modulator of the GABABReceptor, GS39783-Comparison With the Effect of the GABABReceptor Direct Agonist, Baclofen

(2008) Paola Maccioni et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Update on Pharmacologic Options for Smoking Cessation Treatment

(2008) Mitchell Nides   AMERICAN JOURNAL OF MEDICINE

Characterization of (R,S)-5,7-di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one as a positive allosteric modulator of GABAB receptors

(2008) P Malherbe et al.   BRITISH JOURNAL OF PHARMACOLOGY

Baclofen attenuates cue-induced reinstatement of alcohol-seeking behavior in Sardinian alcohol-preferring (sP) rats

(2008) Paola Maccioni et al.   DRUG AND ALCOHOL DEPENDENCE

Nicotinic Acetylcholine α4β2 Receptor Regulates the Motivational Effect of Intracranial Self Stimulation Behavior in the Runway Method

(2008) Hidenori Sagara et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Positive Modulation of GABAB Receptors Decreased Nicotine Self-Administration and Counteracted Nicotine-Induced Enhancement of Brain Reward Function in Rats

(2008) N. E. Paterson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Distinctive nicotinic acetylcholine receptor functional phenotypes of rat ventral tegmental area dopaminergic neurons

(2008) Kechun Yang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Effects of baclofen on conditioned rewarding and discriminative stimulus effects of nicotine in rats

(2008) Bernard Le Foll et al.   NEUROSCIENCE LETTERS