The H3 loop of antibodies shows unique structural characteristics

Length-independent structural similarities enrich the antibody CDR canonical class model

(2016) Jaroslaw Nowak et al.   mAbs

Structural diversity in a human antibody germline library

(2016) Alexey Teplyakov et al.   mAbs

The Origin of CDR H3 Structural Diversity

(2015) Brian D. Weitzner et al.   STRUCTURE

Building a Better Fragment Library for De Novo Protein Structure Prediction

(2015) Saulo H. P. de Oliveira et al.   PLoS One

Second antibody modeling assessment (AMA-II)

(2014) Juan C. Almagro et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

SAbDab: the structural antibody database

(2013) James Dunbar et al.   NUCLEIC ACIDS RESEARCH

Current strategies in antibody engineering: Fc engineering and pH-dependent antigen binding, bispecific antibodies and antibody drug conjugates

(2012) Karen J. Vincent et al.   Biotechnology Journal

Paratome: an online tool for systematic identification of antigen-binding regions in antibodies based on sequence or structure

(2012) Vered Kunik et al.   NUCLEIC ACIDS RESEARCH

Computer-aided antibody design

(2012) D. Kuroda et al.   PROTEIN ENGINEERING DESIGN & SELECTION

A New Clustering of Antibody CDR Loop Conformations

(2010) Benjamin North et al.   JOURNAL OF MOLECULAR BIOLOGY

Analysis of temperature factor distribution in high-resolution protein structures

(2009) S. Parthasarathy et al.   PROTEIN SCIENCE

The Intrinsic Contributions of Tyrosine, Serine, Glycine and Arginine to the Affinity and Specificity of Antibodies

(2008) Sara Birtalan et al.   JOURNAL OF MOLECULAR BIOLOGY

Multi-constraint computational design suggests that native sequences of germline antibody H3 loops are nearly optimal for conformational flexibility

(2008) Mariana Babor et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Reconstruction of Protein Backbones from the BriX Collection of Canonical Protein Fragments

(2008) Lies Baeten et al.   PLoS Computational Biology