Norovirus RNA-dependent RNA polymerase: A computational study of metal-binding preferences

A new paradigm of DNA synthesis: three-metal-ion catalysis

(2016) Wei Yang et al.   Cell and Bioscience

Pcetk: A pDynamo-based Toolkit for Protonation State Calculations in Proteins

(2015) Mikolaj Feliks et al.   Journal of Chemical Information and Modeling

Nonnucleoside Inhibitors of Norovirus RNA Polymerase: Scaffolds for Rational Drug Design

(2014) Auda A. Eltahla et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Polymerases of hepatitis C viruses and flaviviruses: Structural and mechanistic insights and drug development

(2014) Célia Caillet-Saguy et al.   ANTIVIRAL RESEARCH

Investigational nucleoside and nucleotide polymerase inhibitors and their use in treating hepatitis C virus

(2014) Ivan Gentile et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Distinct Conformations of a Putative Translocation Element in Poliovirus Polymerase

(2014) Aaron J. Sholders et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Bases of Norovirus RNA Dependent RNA Polymerase Inhibition by Novel Suramin-Related Compounds

(2014) Romina Croci et al.   PLoS One

Structure of a backtracked state reveals conformational changes similar to the state following nucleotide incorporation in human norovirus polymerase

(2014) Dmitry Zamyatkin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Role of Motif B Loop in Allosteric Regulation of RNA-Dependent RNA Polymerization Activity

(2013) Damià Garriga et al.   JOURNAL OF MOLECULAR BIOLOGY

Norovirus vaccine development: next steps

(2012) Robert L Atmar et al.   Expert Review of Vaccines

Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases

(2012) Eloise Mastrangelo et al.   JOURNAL OF MOLECULAR BIOLOGY

Conformational Changes in Motif D of RdRPs as Fidelity Determinant

(2012) Nuria Verdaguer et al.   STRUCTURE

Motif D of Viral RNA-Dependent RNA Polymerases Determines Efficiency and Fidelity of Nucleotide Addition

(2012) Xiaorong Yang et al.   STRUCTURE

The potential economic value of a human norovirus vaccine for the United States

(2012) Sarah M. Bartsch et al.   VACCINE

What Is the Role of Motif D in the Nucleotide Incorporation Catalyzed by the RNA-dependent RNA Polymerase from Poliovirus?

(2012) Hujun Shen et al.   PLoS Computational Biology

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Molecular Dynamics Simulations of Viral RNA Polymerases Link Conserved and Correlated Motions of Functional Elements to Fidelity

(2011) Ibrahim M. Moustafa et al.   JOURNAL OF MOLECULAR BIOLOGY

VPg-Primed RNA Synthesis of Norovirus RNA-Dependent RNA Polymerases by Using a Novel Cell-Based Assay

(2011) C. V. Subba-Reddy et al.   JOURNAL OF VIROLOGY

The ORCA program system

(2011) Frank Neese   Wiley Interdisciplinary Reviews-Computational Molecular Science

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

pH-Dependent pKaValues in Proteins—A Theoretical Analysis of Protonation Energies with Practical Consequences for Enzymatic Reactions

(2010) Elisa Bombarda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase

(2010) P. Gong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase?

(2009) Craig E Cameron et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Nucleic acid polymerases use a general acid for nucleotidyl transfer

(2009) Christian Castro et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Insights into Mechanisms of Catalysis and Inhibition in Norwalk Virus Polymerase

(2008) Dmitry F. Zamyatkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The pDynamo Program for Molecular Simulations using Hybrid Quantum Chemical and Molecular Mechanical Potentials

(2008) Martin J. Field   Journal of Chemical Theory and Computation