Biological and functional relevance of CASP predictions

The Human Gene Mutation Database: towards a comprehensive repository of inherited mutation data for medical research, genetic diagnosis and next-generation sequencing studies

(2017) Peter D. Stenson et al.   HUMAN GENETICS

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Biological function derived from predicted structures in CASP11

(2016) Peter J. Huwe et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structure of the STRA6 receptor for retinol uptake

(2016) Y. Chen et al.   SCIENCE

Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking

(2016) B. N. Dubey et al.   Science Advances

Relating Essential Proteins to Drug Side-Effects Using Canonical Component Analysis: A Structure-Based Approach

(2015) Tianyun Liu et al.   Journal of Chemical Information and Modeling

IntFOLD: an integrated server for modelling protein structures and functions from amino acid sequences: Figure 1.

(2015) Liam J. McGuffin et al.   NUCLEIC ACIDS RESEARCH

ClinVar: public archive of interpretations of clinically relevant variants

(2015) Melissa J. Landrum et al.   NUCLEIC ACIDS RESEARCH

Some of the most interesting CASP11 targets through the eyes of their authors

(2015) Andriy Kryshtafovych et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Template based protein structure modeling by global optimization in CASP11

(2015) Keehyoung Joo et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Signal Transduction in Histidine Kinases: Insights from New Structures

(2015) Manasi P. Bhate et al.   STRUCTURE

Variations in the Binding Pocket of an Inhibitor of the Bacterial Division Protein FtsZ across Genotypes and Species

(2015) Amanda Miguel et al.   PLoS Computational Biology

Designing and evaluating the MULTICOM protein local and global model quality prediction methods in the CASP10 experiment

(2014) Renzhi Cao et al.   BMC STRUCTURAL BIOLOGY

Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10

(2013) Andriy Kryshtafovych et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Identification ofDPAGT1as a new gene in which mutations cause a congenital myasthenic syndrome

(2012) Katsiaryna Belaya et al.   Annals of the New York Academy of Sciences

SiteComp: a server for ligand binding site analysis in protein structures

(2012) Yingjie Lin et al.   BIOINFORMATICS

Using RosettaLigand for Small Molecule Docking into Comparative Models

(2012) Kristian W. Kaufmann et al.   PLoS One

Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction

(2011) Andriy Kryshtafovych et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Using Multiple Microenvironments to Find Similar Ligand-Binding Sites: Application to Kinase Inhibitor Binding

(2011) Tianyun Liu et al.   PLoS Computational Biology

A unified statistical model to support local sequence order independent similarity searching for ligand-binding sites and its application to genome-based drug discovery

(2009) L. Xie et al.   BIOINFORMATICS

Fpocket: An open source platform for ligand pocket detection

(2009) Vincent Le Guilloux et al.   BMC BIOINFORMATICS