Structure of the WD40-domain of human ATG16L1

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

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Digesting the Expanding Mechanisms of Autophagy

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TMEM166/EVA1A interacts with ATG16L1 and induces autophagosome formation and cell death

(2016) Jia Hu et al.   Cell Death & Disease

The T300A Crohn’s disease risk polymorphism impairs function of the WD40 domain of ATG16L1

(2016) Emilio Boada-Romero et al.   Nature Communications

TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity

(2015) Tomonori Kimura et al.   JOURNAL OF CELL BIOLOGY

Autophagy and neurodegeneration

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The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

Autophagy in cellular metabolism and cancer

(2015) Xuejun Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunologic manifestations of autophagy

(2015) Vojo Deretic et al.   JOURNAL OF CLINICAL INVESTIGATION

Organelle-Specific Initiation of Autophagy

(2015) Valentina Sica et al.   MOLECULAR CELL

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Molecular Mechanism of Autophagic Membrane-Scaffold Assembly and Disassembly

(2014) Anna Kaufmann et al.   CELL

WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1

(2014) Hannah C. Dooley et al.   MOLECULAR CELL

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3

(2014) Aditya Murthy et al.   NATURE

SMART: recent updates, new developments and status in 2015

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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

(2014) K. G. Lassen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The machinery of macroautophagy

(2013) Yuchen Feng et al.   CELL RESEARCH

TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3

(2013) Emilio Boada-Romero et al.   EMBO JOURNAL

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin

(2013) Naonobu Fujita et al.   JOURNAL OF CELL BIOLOGY

Autophagy and Crohn's Disease

(2013) Hang Thi Thu Nguyen et al.   Journal of Innate Immunity

Scalable web services for the PSIPRED Protein Analysis Workbench

(2013) Daniel W. A. Buchan et al.   NUCLEIC ACIDS RESEARCH

The N-Terminal Region of the Human Autophagy Protein ATG16L1 Contains a Domain That Folds into a Helical Structure Consistent with Formation of a Coiled-Coil

(2013) Rhiannon Parkhouse et al.   PLoS One

Mechanisms of Autophagosome Biogenesis

(2012) David C. Rubinsztein et al.   CURRENT BIOLOGY

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

(2012) Julia Romanov et al.   EMBO JOURNAL

Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex–dependent and –independent autophagy

(2012) Noor Gammoh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy

(2012) Chinatsu Otomo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Structure and function of WD40 domain proteins

(2011) Chao Xu et al.   Protein & Cell

MBSJ MCC Young Scientist Award 2009
REVIEW: Selective autophagy regulates various cellular functions

(2010) Masaaki Komatsu et al.   GENES TO CELLS

WD40 proteins propel cellular networks

(2010) Christian U. Stirnimann et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dimeric Coiled-coil Structure ofSaccharomyces cerevisiaeAtg16 and Its Functional Significance in Autophagy

(2009) Yuko Fujioka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

Crohn's Disease, Autophagy, and the Paneth Cell

(2009) Daniel J. Klionsky   NEW ENGLAND JOURNAL OF MEDICINE

Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation

(2008) Takashi Itoh et al.   MOLECULAR BIOLOGY OF THE CELL

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL