Is there a future for genome-editing technologies in conservation?

Alien species as a driver of recent extinctions

(2016) Céline Bellard et al.   Biology Letters

The Heroes of CRISPR

(2016) Eric S. Lander   CELL

Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering

(2016) Addison V. Wright et al.   CELL

Synthetic bugs on the loose: containment options for deeply engineered (micro)organisms

(2016) Markus Schmidt et al.   CURRENT OPINION IN BIOTECHNOLOGY

Merging DNA metabarcoding and ecological network analysis to understand and build resilient terrestrial ecosystems

(2016) Darren M. Evans et al.   FUNCTIONAL ECOLOGY

Recent Progress in CRISPR/Cas9 Technology

(2016) Yue Mei et al.   Journal of Genetics and Genomics

Natural history collections as windows on evolutionary processes

(2016) Michael W. Holmes et al.   MOLECULAR ECOLOGY

Cheating evolution: engineering gene drives to manipulate the fate of wild populations

(2016) Jackson Champer et al.   NATURE REVIEWS GENETICS

Harnessing the power of RADseq for ecological and evolutionary genomics

(2016) Kimberly R. Andrews et al.   NATURE REVIEWS GENETICS

Invasive mammal eradication on islands results in substantial conservation gains

(2016) Holly P. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advances in therapeutic CRISPR/Cas9 genome editing

(2016) Nataša Savić et al.   Translational Research

Emerging Technologies to Conserve Biodiversity: Further Opportunities via Genomics. Response to Pimm et al.

(2016) Helen R. Taylor et al.   TRENDS IN ECOLOGY & EVOLUTION

Genetic Control Of Malaria Mosquitoes

(2016) Kyle Jarrod McLean et al.   TRENDS IN PARASITOLOGY

Recovery of gene diversity using long-term cryopreserved spermatozoa and artificial insemination in the endangered black-footed ferret

(2015) J. G. Howard et al.   ANIMAL CONSERVATION

The next generation of rodent eradications: Innovative technologies and tools to improve species specificity and increase their feasibility on islands

(2015) Karl J. Campbell et al.   BIOLOGICAL CONSERVATION

Non-target species mortality and the measurement of brodifacoum rodenticide residues after a rat (Rattus rattus) eradication on Palmyra Atoll, tropical Pacific

(2015) William C. Pitt et al.   BIOLOGICAL CONSERVATION

Connecting genotypes, phenotypes and fitness: harnessing the power of CRISPR/Cas9 genome editing

(2015) Jeremy M. Bono et al.   MOLECULAR ECOLOGY

Agriculture: A new breed of edits

(2015) Claire Ainsworth   NATURE

Biocontainment of genetically modified organisms by synthetic protein design

(2015) Daniel J. Mandell et al.   NATURE

Protective alleles and modifier variants in human health and disease

(2015) Andrew R. Harper et al.   NATURE REVIEWS GENETICS

Brave New Genome

(2015) Eric S. Lander   NEW ENGLAND JOURNAL OF MEDICINE

Opinion: Is CRISPR-based gene drive a biocontrol silver bullet or global conservation threat?: Fig. 1.

(2015) Bruce L. Webber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs

(2015) Clare D. Marsden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Making the cut

(2015) J. Travis   SCIENCE

Safeguarding gene drive experiments in the laboratory

(2015) O. S. Akbari et al.   SCIENCE

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

(2015) M. Tabebordbar et al.   SCIENCE

Conservation archaeogenomics: ancient DNA and biodiversity in the Anthropocene

(2015) Courtney A. Hofman et al.   TRENDS IN ECOLOGY & EVOLUTION

Emerging Technologies to Conserve Biodiversity

(2015) Stuart L. Pimm et al.   TRENDS IN ECOLOGY & EVOLUTION

Genomics and the challenging translation into conservation practice

(2015) Aaron B.A. Shafer et al.   TRENDS IN ECOLOGY & EVOLUTION

Higher-order genetic interactions and their contribution to complex traits

(2015) Matthew B. Taylor et al.   TRENDS IN GENETICS

Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic

(2015) Vincent J. Lynch et al.   Cell Reports

Invasive rats on tropical islands: Their population biology and impacts on native species

(2015) Grant A. Harper et al.   Global Ecology and Conservation

Switching on sex: transcriptional regulation of the testis-determining gene Sry

(2014) C. Larney et al.   DEVELOPMENT

The role of global trade and transport network topology in the human-mediated dispersal of alien species

(2014) Natalie Clare Banks et al.   ECOLOGY LETTERS

Using genomics to characterize evolutionary potential for conservation of wild populations

(2014) Katherine A. Harrisson et al.   Evolutionary Applications

Cryptic genetic variation: evolution's hidden substrate

(2014) Annalise B. Paaby et al.   NATURE REVIEWS GENETICS

Synthetic biology and the conservation of biodiversity

(2014) Kent H. Redford et al.   ORYX

Regulating gene drives

(2014) K. A. Oye et al.   SCIENCE

Concerning RNA-guided gene drives for the alteration of wild populations

(2014) Kevin M Esvelt et al.   eLife

Ecology: Gene tweaking for conservation

(2013) Michael A. Thomas et al.   NATURE

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Cryptic genetic variation promotes rapid evolutionary adaptation in an RNA enzyme

(2011) Eric J. Hayden et al.   NATURE

MHC genotypes associate with resistance to a frog-killing fungus

(2011) A. E. Savage et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Congenital bone deformities and the inbred wolves (Canis lupus) of Isle Royale

(2009) Jannikke Räikkönen et al.   BIOLOGICAL CONSERVATION

The value of avian genomics to the conservation of wildlife

(2009) Michael N Romanov et al.   BMC GENOMICS