Dimerization of Tie2 mediated by its membrane-proximal FNIII domains

Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization

(2017) Veli-Matti Leppänen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation

(2016) Minah Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Tie1 controls angiopoietin function in vascular remodeling and inflammation

(2016) Emilia A. Korhonen et al.   JOURNAL OF CLINICAL INVESTIGATION

Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity

(2016) Tomokazu Souma et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting Tie2 and the host vascular response in sepsis

(2016) Samir M. Parikh   Science Translational Medicine

Ligand regulation of a constitutively dimeric EGF receptor

(2015) Daniel M. Freed et al.   Nature Communications

The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells

(2015) Soniya Savant et al.   Cell Reports

Tie2 and Eph Receptor Tyrosine Kinase Activation and Signaling

(2014) W. A. Barton et al.   Cold Spring Harbor Perspectives in Biology

How IGF-1 activates its receptor

(2014) Jennifer M Kavran et al.   eLife

Ligand-independent Tie2 Dimers Mediate Kinase Activity Stimulated by High Dose Angiopoietin-1

(2013) Daishi Yamakawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses

(2013) Elena Seiradake et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5

(2013) Kai Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region

(2013) A. V. Reshetnyak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for angiopoietin-1-mediated signaling initiation

(2013) X. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor Tyrosine Kinase-Mediated Angiogenesis

(2013) M. Jeltsch et al.   Cold Spring Harbor Perspectives in Biology

Biology of the TAM Receptors

(2013) G. Lemke   Cold Spring Harbor Perspectives in Biology

Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization

(2010) Denis Tvorogov et al.   CANCER CELL

Angiopoietin-4 Promotes Glioblastoma Progression by Enhancing Tumor Cell Viability and Angiogenesis

(2010) M. K. Brunckhorst et al.   CANCER RESEARCH

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

Tie1-Tie2 Interactions Mediate Functional Differences between Angiopoietin Ligands

(2010) Tom C.M. Seegar et al.   MOLECULAR CELL

An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly

(2010) Elena Seiradake et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Oligomerized Tie2 localizes to clathrin-coated pits in response to angiopoietin-1

(2009) Elena Bogdanovic et al.   HISTOCHEMISTRY AND CELL BIOLOGY

DAMMIF, a program for rapidab-initioshape determination in small-angle scattering

(2009) Daniel Franke et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Angiopoietin 2 Is a Partial Agonist/Antagonist of Tie2 Signaling in the Endothelium

(2009) H. T. Yuan et al.   MOLECULAR AND CELLULAR BIOLOGY

Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system

(2009) Hellmut G. Augustin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural Analysis of Sensor Domains from the TMAO-Responsive Histidine Kinase Receptor TorS

(2009) Jason O. Moore et al.   STRUCTURE

Differential function of Tie2 at cell–cell contacts and cell–substratum contacts regulated by angiopoietin-1

(2008) Shigetomo Fukuhara et al.   NATURE CELL BIOLOGY

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts

(2008) Pipsa Saharinen et al.   NATURE CELL BIOLOGY