Mechanism of DNA alkylation-induced transcriptional stalling, lesion bypass, and mutagenesis
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Title
Mechanism of DNA alkylation-induced transcriptional stalling, lesion bypass, and mutagenesis
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 34, Pages E7082-E7091
Publisher
Proceedings of the National Academy of Sciences
Online
2017-08-08
DOI
10.1073/pnas.1708748114
References
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- (2013) Nisana Andersen et al. CHEMICAL RESEARCH IN TOXICOLOGY
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- (2010) Kresten Lindorff-Larsen et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
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