DYRK1A regulates Hap1–Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome

Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial

(2016) Rafael de la Torre et al.   LANCET NEUROLOGY

Postnatal Loss of Hap1 Reduces Hippocampal Neurogenesis and Causes Adult Depressive-Like Behavior in Mice

(2015) Jianxing Xiang et al.   PLoS Genetics

The Down syndrome-related protein kinase DYRK1A phosphorylates p27Kip1and Cyclin D1 and induces cell cycle exit and neuronal differentiation

(2014) Ulf Soppa et al.   CELL CYCLE

Phosphorylation and Inactivation of Glycogen Synthase Kinase 3β (GSK3β) by Dual-specificity Tyrosine Phosphorylation-regulated Kinase 1A (Dyrk1A)

(2014) Woo-Joo Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Huntingtin-associated protein 1 regulates postnatal neurogenesis and neurotrophin receptor sorting

(2013) Jianxing Xiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Dosage of Dyrk1a Shifts Cells within a p21-Cyclin D1 Signaling Map to Control the Decision to Enter the Cell Cycle

(2013) Jia-Yun Chen et al.   MOLECULAR CELL

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans

(2013) Rafael De la Torre et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Wdr68 Requires Nuclear Access for Craniofacial Development

(2013) Bingyan Wang et al.   PLoS One

Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression

(2012) Claudia Fuchs et al.   LABORATORY INVESTIGATION

DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation

(2011) Yoshihiko Miyata et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Transcript catalogs of human chromosome 21 and orthologous chimpanzee and mouse regions

(2011) Xiaolu Sturgeon et al.   MAMMALIAN GENOME

Interaction of ataxin-3 with huntingtin-associated protein 1 through Josephin domain

(2011) Yukio Takeshita et al.   NEUROREPORT

MNB/DYRK1A as a multiple regulator of neuronal development

(2010) Francisco J. Tejedor et al.   FEBS Journal

Dyrk1A Binds to Multiple Endocytic Proteins Required for Formation of Clathrin-Coated Vesicles

(2009) Noriko Murakami et al.   BIOCHEMISTRY

Function and regulation of Dyrk1A: towards understanding Down syndrome

(2009) Joongkyu Park et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice

(2008) Guoqing Sheng et al.   JOURNAL OF CLINICAL INVESTIGATION