Activation mechanism of the G protein-coupled sweet receptor heterodimer with sweeteners and allosteric agonists

The anatomy of mammalian sweet taste receptors

(2017) Jean-Baptiste Chéron et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V fromSiraitia grosvenorii

(2016) Maxim Itkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional Implications

(2016) Vaclav Cvicek et al.   PLoS Computational Biology

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain

(2014) Andrew S. Doré et al.   NATURE

Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer

(2014) Li Xue et al.   Nature Chemical Biology

Ligand- and mutation-induced conformational selection in the CCR5 chemokine G protein-coupled receptor

(2014) R. Abrol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator

(2014) H. Wu et al.   SCIENCE

Crystal structure of oligomeric β1-adrenergic G protein–coupled receptors in ligand-free basal state

(2013) Jianyun Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors

(2013) E. Doumazane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Psychometric and Taste Receptor Responses to Steviol Glycosides

(2012) Caroline Hellfritsch et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Structure of the human κ-opioid receptor in complex with JDTic

(2012) Huixian Wu et al.   NATURE

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

(2012) Aashish Manglik et al.   NATURE

Characterization of the Modes of Binding between Human Sweet Taste Receptor and Low-Molecular-Weight Sweet Compounds

(2012) Katsuyoshi Masuda et al.   PLoS One

Recombinant expression, in vitro refolding, and biophysical characterization of the N-terminal domain of T1R3 taste receptor

(2012) Elodie Maîtrepierre et al.   PROTEIN EXPRESSION AND PURIFICATION

Molecular basis for dramatic changes in cannabinoid CB1 G protein-coupled receptor activation upon single and double point mutations

(2012) Caitlin E. Scott et al.   PROTEIN SCIENCE

Molecular Mechanism of Species-Dependent Sweet Taste toward Artificial Sweeteners

(2011) B. Liu et al.   JOURNAL OF NEUROSCIENCE

Bihelix: Towards de novo structure prediction of an ensemble of G-protein coupled receptor conformations

(2011) Ravinder Abrol et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Signaling by Sensory Receptors

(2011) D. Julius et al.   Cold Spring Harbor Perspectives in Biology

Molecular mechanism of the sweet taste enhancers

(2010) F. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanism for the umami taste synergism

(2008) F. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA