Loss-of-function mutation inMirta22/Emc10rescues specific schizophrenia-related phenotypes in a mouse model of the 22q11.2 deletion

A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia

(2016) Timothy Hughes et al.   BIOLOGICAL PSYCHIATRY

A loss of function variant in CASP7 protects against Alzheimer’s disease in homozygous APOE ε4 allele carriers

(2016) Kristin L. Ayers et al.   BMC GENOMICS

PCSK9 R46L Loss-of-Function Mutation Reduces Lipoprotein(a), LDL Cholesterol, and Risk of Aortic Valve Stenosis

(2016) Anne Langsted et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Impact of Cognitive and Social Cognitive Impairment on Functional Outcomes in Patients With Schizophrenia

(2016) Michael F. Green   JOURNAL OF CLINICAL PSYCHIATRY

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Age-Dependent Specific Changes in Area CA2 of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome

(2016) Rebecca A. Piskorowski et al.   NEURON

Developmental Inhibition of Gsk3 Rescues Behavioral and Neurophysiological Deficits in a Mouse Model of Schizophrenia Predisposition

(2016) Makoto Tamura et al.   NEURON

Social cognition, social competence, negative symptoms and social outcomes: Inter-relationships in people with schizophrenia

(2015) Marc Kalin et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration

(2015) A Ferrés-Coy et al.   MOLECULAR PSYCHIATRY

Perspective: Enforce the clinical guidelines

(2015) Monique Roobol   NATURE

Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy

(2015) Asami Kondo et al.   NATURE

Protective alleles and modifier variants in human health and disease

(2015) Andrew R. Harper et al.   NATURE REVIEWS GENETICS

Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci

(2015) Stephan J. Sanders et al.   NEURON

Molecular Substrates of Altered Axonal Growth and Brain Connectivity in a Mouse Model of Schizophrenia

(2015) Jun Mukai et al.   NEURON

Reducing Ventral Tegmental Dopamine D2 Receptor Expression Selectively Boosts Incentive Motivation

(2015) Johannes W de Jong et al.   NEUROPSYCHOPHARMACOLOGY

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

(2015) M. Tabebordbar et al.   SCIENCE

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

(2015) C. E. Nelson et al.   SCIENCE

Hopes rise for new Alzheimer’s drug after secondary analysis:

(2015) Nigel Hawkes   BMJ-British Medical Journal

Prepulse inhibition predicts spatial working memory performance in the inbred Roman high- and low-avoidance rats and in genetically heterogeneous NIH-HS rats: relevance for studying pre-attentive and cognitive anomalies in schizophrenia

(2015) Ignasi Oliveras et al.   Frontiers in Behavioral Neuroscience

Hopes rise for new Alzheimer’s drug after secondary analysis:

(2015) Nigel Hawkes   BMJ-British Medical Journal

Glioblastoma exosomes and IGF-1R/AS-ODN are immunogenic stimuli in a translational research immunotherapy paradigm

(2014) Larry A. Harshyne et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing

(2014) Qiurong Ding et al.   CIRCULATION RESEARCH

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

(2014) Jason Flannick et al.   NATURE GENETICS

Encoding of fear learning and memory in distributed neuronal circuits

(2014) Cyril Herry et al.   NATURE NEUROSCIENCE

Tests of unconditioned anxiety — Pitfalls and disappointments

(2014) A. Ennaceur   PHYSIOLOGY & BEHAVIOR

Derepression of a Neuronal Inhibitor due to miRNA Dysregulation in a Schizophrenia-Related Microdeletion

(2013) Bin Xu et al.   CELL

Short-Term Plasticity Explains Irregular Persistent Activity in Working Memory Tasks

(2013) D. Hansel et al.   JOURNAL OF NEUROSCIENCE

The Pattern of Cortical Dysfunction in a Mouse Model of a Schizophrenia-Related Microdeletion

(2013) K. Fenelon et al.   JOURNAL OF NEUROSCIENCE

An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study

(2013) Timothy M Miller et al.   LANCET NEUROLOGY

Evidence that duplications of 22q11.2 protect against schizophrenia

(2013) E Rees et al.   MOLECULAR PSYCHIATRY

The contextual brain: implications for fear conditioning, extinction and psychopathology

(2013) Stephen Maren et al.   NATURE REVIEWS NEUROSCIENCE

Prepulse inhibition predicts working memory performance whilst startle habituation predicts spatial reference memory retention in C57BL/6 mice

(2012) Philipp Singer et al.   BEHAVIOURAL BRAIN RESEARCH

Activity-Dependent Local Translation of Matrix Metalloproteinase-9

(2012) M. Dziembowska et al.   JOURNAL OF NEUROSCIENCE

Copy Number Variants in Schizophrenia: Confirmation of Five Previous Findings and New Evidence for 3q29 Microdeletions and VIPR2 Duplications

(2011) Douglas F. Levinson et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Genetic Architecture of Schizophrenia: New Mutations and Emerging Paradigms

(2011) Laura Rodriguez-Murillo et al.   Annual Review of Medicine

Evidence for altered hippocampal function in a mouse model of the human 22q11.2 microdeletion

(2011) Liam J. Drew et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Defining human ERAD networks through an integrative mapping strategy

(2011) John C. Christianson et al.   NATURE CELL BIOLOGY

Discrete Forebrain Neuronal Networks Supporting Noradrenergic Regulation of Sensorimotor Gating

(2011) Karen M Alsene et al.   NEUROPSYCHOPHARMACOLOGY

The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors

(2011) Ana Luisa Terzian et al.   Frontiers in Behavioral Neuroscience

MicroRNAs in psychiatric and neurodevelopmental disorders

(2010) Bin Xu et al.   BRAIN RESEARCH

hHSS1: a novel secreted factor and suppressor of glioma growth located at chromosome 19q13.33

(2010) Katiana S. Junes-Gill et al.   JOURNAL OF NEURO-ONCOLOGY

Impaired hippocampal–prefrontal synchrony in a genetic mouse model of schizophrenia

(2010) Torfi Sigurdsson et al.   NATURE

22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia

(2010) Maria Karayiorgou et al.   NATURE REVIEWS NEUROSCIENCE

Reduced Expression of IFIH1 Is Protective for Type 1 Diabetes

(2010) Kate Downes et al.   PLoS One

Functional and Dysfunctional Synaptic Plasticity in Prefrontal Cortex: Roles in Psychiatric Disorders

(2009) Yukiori Goto et al.   BIOLOGICAL PSYCHIATRY

Cognition in Mouse Models of Schizophrenia Susceptibility Genes

(2009) P. A. Arguello et al.   SCHIZOPHRENIA BULLETIN

Modeling the Positive Symptoms of Schizophrenia in Genetically Modified Mice: Pharmacology and Methodology Aspects

(2009) M. van den Buuse   SCHIZOPHRENIA BULLETIN

Correlation of prepulse inhibition and Wisconsin Card Sorting Test in schizophrenia and controls: Effects of smoking status

(2009) Rachel A. Rabin et al.   SCHIZOPHRENIA RESEARCH

Rare chromosomal deletions and duplications increase risk of schizophrenia

(2008) Jennifer L. Stone et al.   NATURE

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

(2008) Kimberly L Stark et al.   NATURE GENETICS

Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion

(2008) Jun Mukai et al.   NATURE NEUROSCIENCE

Synaptic Theory of Working Memory

(2008) G. Mongillo et al.   SCIENCE

BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory?

(2007) Yuan Lu et al.   NEUROBIOLOGY OF LEARNING AND MEMORY