Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

(2016) Xiaoyan Robert Bao et al.   eLife

Atomic structure of the apoptosome: mechanism of cytochromec- and dATP-mediated activation of Apaf-1

(2015) Mengying Zhou et al.   GENES & DEVELOPMENT

Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome

(2014) Qi Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beam-induced motion correction for sub-megadalton cryo-EM particles

(2014) Sjors HW Scheres   eLife

Apoptosome and inflammasome: conserved machineries for caspase activation

(2014) Jijie Chai et al.   National Science Review

Proteolytic Processing of the Caspase-9 Zymogen Is Required for Apoptosome-mediated Activation of Caspase-9

(2013) Qi Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

The Holo-Apoptosome: Activation of Procaspase-9 and Interactions with Caspase-3

(2011) Shujun Yuan et al.   STRUCTURE

Structure of an Apoptosome-Procaspase-9 CARD Complex

(2010) Shujun Yuan et al.   STRUCTURE