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Neurosciences
Julian Day-Cooney, Jackson J. Cone, John H. R. Maunsell
Summary: This study examines how spikes occurring at different times contribute to visual perception and action. The researchers used optogenetic stimulation to excite inhibitory interneurons in the visual cortex of mice and found that spikes occurring early in response to a visual stimulus play a crucial role in guiding behavior.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
Yajie Liang, Jiang Lan Fan, Wenzhi Sun, Rongwen Lu, Ming Chen, Na Ji
Summary: Researchers have identified a population of layer 6 excitatory neurons in the primary visual cortex of mice that serve as the main conveyer of transcallosal information. These neurons contribute to a reciprocal network across multiple sensory cortices in two hemispheres, encoding orientation, direction, and receptive field information. The spontaneous activity of these neurons exhibits complex relationships with brain states and stimulus presentation, distinguishing them from other neuron populations.
Article
Neurosciences
Shang Feng, Zhichang Cui, Zhengqi Han, Hongjian Li, Hongbo Yu
Summary: This study explores the contribution of neural plasticity to the saliency detection of temporally distributed visual streams. The results show that neuronal responses are potentiated when the probability of a biased orientation is slightly higher than others, and suppressed when the probability becomes much higher. This bidirectional plasticity is induced by the competition between excitatory and inhibitory components of V1 neuronal receptive field.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Anatomy & Morphology
Matthew Adusei, J. Michael Hasse, Farran Briggs
Summary: Direct feedback connections from mid-level extrastriate visual cortex to the LGN were observed, supporting complementary reciprocal circuits at multiple processing stages. These connections could provide a substrate for residual vision following V1 damage, different from V1.
BRAIN STRUCTURE & FUNCTION
(2021)
Article
Mathematical & Computational Biology
Allison J. Murphy, Luke Shaw, J. Michael Hasse, Robbe L. T. Goris, Farran Briggs
Summary: The study found that corticogeniculate feedback can increase information coding capacity by stabilizing the response gain of LGN neurons. Optogenetic activation of corticogeniculate neurons reduces LGN gain variability and enhances information coding capacity.
JOURNAL OF COMPUTATIONAL NEUROSCIENCE
(2021)
Article
Neurosciences
Benjamin S. Lankow, W. Martin Usrey
Summary: Parallel processing streams in the brain play important roles in visual processing. The lateral geniculate nucleus (LGN) in the dorsal thalamus is a model for studying the functional specialization of parallel visual streams. This study explored the relationship between extraclassical surround suppression and the parallel channels in the LGN, the magnitude of binocular interaction, and the magnitude of suppression elicited by perceptual competition in each stream. The findings indicate that the Off channel cells contribute to surround suppression and LGN neurons are primarily influenced by stimulation of the dominant eye.
FRONTIERS IN SYSTEMS NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Demetrio Ferro, Jochem van Kempen, Michael Boyd, Stefano Panzeri, Alexander Thiele
Summary: The study revealed how visual information flows between cortical layers within and between macaque brain areas V1 and V4, showing dominance of information flow in certain directions and layers based on attentional modulation. Low-frequency communication was stronger from V4 to V1, with little layer specificity, while gamma-band communication was stronger in the feedforward direction. Attention decreased communication within V1 layers but increased communication within V4 and from V1 to V4 across all frequencies, showing that top-down cognitive processes play a role in modulating communication in the brain.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biology
Martin A. Spacek, Davide Crombie, Yannik Bauer, Gregory Born, Xinyu Liu, Steffen Katzner, Laura Busse
Summary: Neurons in the dLGN receive modulatory inputs from CT feedback and brain stem nuclei. CT feedback consistently increases dLGN response gain and promotes tonic firing for naturalistic movie clips, while its effects on firing rates for gratings are mixed. The neural signatures of CT feedback closely resemble those of behavioral state, but the effects of behavioral state on responses to movies persist even when CT feedback is suppressed.
Article
Biochemistry & Molecular Biology
Paolo Papale, Feng Wang, A. Tyler Morgan, Xing Chen, Amparo Gilhuis, Lucy S. Petro, Lars Muckli, Pieter R. Roelfsema, Matthew W. Self
Summary: This study reveals that contextual information has a rapid and selective impact on neuronal activity in the V1 region of the brain, it can be used to decode scenes and can be predicted from feedforward input. Additionally, the structure of V1 representations measured with electrophysiology in monkeys correlates strongly with the representations measured with fMRI in humans.
Article
Biology
Polina Iamshchinina, Daniel Kaiser, Renat Yakupov, Daniel Haenelt, Alessandro Sciarra, Hendrik Mattern, Falk Luesebrink, Emrah Duezel, Oliver Speck, Nikolaus Weiskopf, Radoslaw Martin Cichy
Summary: Through high-resolution fMRI studies, researchers found that there is a functional and anatomical compartmentalization in the early visual cortex that segregates external and internally-generated visual contents, thus reflecting a general strategy for implementing multiple cognitive functions within a single brain region.
COMMUNICATIONS BIOLOGY
(2021)
Article
Multidisciplinary Sciences
Vandana Sampathkumar, Andrew Miller-Hansen, S. Murray Sherman, Narayanan Kasthuri
Summary: The study found that higher order thalamic neurons integrate signals from different cortical populations, with a significant convergence of inputs from the somatosensory and motor cortices on these neurons. These neurons are not simply relaying afferent information but instead integrating signals from disparate cortical regions, indicating a complex role of the higher order thalamus in overall cortical functioning.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biology
Lucy S. Petro, Fraser W. Smith, Clement Abbatecola, Lars Muckli
Summary: Higher levels of our visual systems process information from broad regions of our visual space, while earlier levels respond to small detailed visual features. The connection between high- and low-level visual areas plays a crucial role in visual perception. Our study found that early visual areas receive feedback information that generalises across images with spatial displacement, which contributes to our understanding of the modulation of early visual areas by higher areas.
Article
Multidisciplinary Sciences
Xunda Wang, Alex T. L. Leong, Shawn Z. K. Tan, Eddie C. Wong, Yilong Liu, Lee-Wei Lim, Ed X. Wu
Summary: Study shows that optogenetically-evoked somatosensory thalamic spindle-like activity enhances memory performance in male rats, suggesting that spindle activities support memory consolidation.
NATURE COMMUNICATIONS
(2023)
Article
Neurosciences
Christini Katsanevaki, Andre M. Bastos, Hayriye Cagnan, Conrado A. Bosman, Karl J. Friston, Pascal Fries
Summary: Selective attention enhances the influence of specific synaptic inputs on higher-area neurons, enabling preferential routing of attended stimuli. Presynaptic circuits, influenced by top-down attentional signals, play a crucial role in selective routing by selectively entraining postsynaptic neurons. The study demonstrates that attentional modulation of intrinsic connections in the visual cortex mediates selective entrainment, providing an explanation for the observed phenomenon.
Article
Neurosciences
Kimberly Reinhold, Arbora Resulaj, Massimo Scanziani
Summary: The state of a mammal's behavior affects how the brain responds to visual stimuli, particularly in the dorsolateral geniculate nucleus (dLGN) of the thalamus, which is responsible for relaying visual information to the cortex. Silencing cortico-thalamic feedback in male and female mice reduces state-dependent differences in dLGN neuron responses to visual stimuli, both in terms of temporal and spatial features. These findings highlight the importance of cortico-thalamic feedback in the state-dependent shift of early visual processing.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Elise M. Bragg, Elizabeth A. Fairless, Shiyuan Liu, Farran Briggs
JOURNAL OF COMPARATIVE NEUROLOGY
(2017)
Article
Neurosciences
Farran Briggs, Caitlin W. Kiley, Edward M. Callaway, W. Martin Usrey
Article
Neurosciences
J. Michael Hasse, Elise M. Bragg, Allison J. Murphy, Farran Briggs
JOURNAL OF COMPARATIVE NEUROLOGY
(2019)
Article
Neurosciences
Vanessa L. Mock, Kimberly L. Luke, Jacqueline R. Hembrook-Short, Farran Briggs
JOURNAL OF NEUROPHYSIOLOGY
(2018)
Article
Neurosciences
Farran Briggs, W. Martin Usrey
JOURNAL OF NEUROSCIENCE
(2011)
Article
Neurosciences
Allan T. Gulledge, Sameera Dasari, Keita Onoue, Emily K. Stephens, J. Michael Hasse, Daniel Avesar
JOURNAL OF NEUROSCIENCE
(2013)
Article
Neurosciences
Andre M. Bastos, Farran Briggs, Henry J. Alitto, George R. Mangun, W. Martin Usrey
JOURNAL OF NEUROSCIENCE
(2014)
Article
Multidisciplinary Sciences
Farran Briggs, George R. Mangun, W. Martin Usrey
Article
Neurosciences
Vanessa L. Mock, Kimberly L. Luke, Jacqueline R. Hembrook-Short, Farran Briggs
JOURNAL OF NEUROPHYSIOLOGY
(2019)
Article
Neurosciences
Jacqueline R. Hembrook-Short, Vanessa L. Mock, W. Martin Usrey, Farran Briggs
JOURNAL OF NEUROSCIENCE
(2019)
Article
Mathematical & Computational Biology
Allison J. Murphy, Luke Shaw, J. Michael Hasse, Robbe L. T. Goris, Farran Briggs
Summary: The study found that corticogeniculate feedback can increase information coding capacity by stabilizing the response gain of LGN neurons. Optogenetic activation of corticogeniculate neurons reduces LGN gain variability and enhances information coding capacity.
JOURNAL OF COMPUTATIONAL NEUROSCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Jacqueline R. Hembrook-Short, Vanessa L. Mock, Farran Briggs