Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1

Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates

(2015) P. Ann Boriack-Sjodin et al.   ACS Chemical Biology

Chemical Biology of Protein Arginine Modifications in Epigenetic Regulation

(2015) Jakob Fuhrmann et al.   CHEMICAL REVIEWS

Functional insights from high resolution structures of mouse protein arginine methyltransferase 6

(2015) Luc Bonnefond et al.   JOURNAL OF STRUCTURAL BIOLOGY

Arginine methyltransferases as novel therapeutic targets for breast cancer

(2015) A. Morettin et al.   MUTAGENESIS

Synthesis and evaluation of protein arginine N-methyltransferase inhibitors designed to simultaneously occupy both substrate binding sites

(2015) Matthijs van Haren et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structural Determinants for the Strict Monomethylation Activity by Trypanosoma brucei Protein Arginine Methyltransferase 7

(2014) Chongyuan Wang et al.   STRUCTURE

Structural insight into arginine methylation by the mouse protein arginine methyltransferase 7: a zinc finger freezes the mimic of the dimeric state into a single active site

(2014) Vincent Cura et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Protein arginine methylation of non-histone proteins and its role in diseases

(2013) Han Wei et al.   CELL CYCLE

Overexpression of CARM1 in breast cancer is correlated with poorly characterized clinicopathologic parameters and molecular subtypes

(2013) Hongxia Cheng et al.   Diagnostic Pathology

Protein arginine methyltransferases (PRMTs) as therapeutic targets

(2012) Boksik Cha et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Crystal structure of the human PRMT5:MEP50 complex

(2012) S. Antonysamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural basis for CARM1 inhibition by indole and pyrazole inhibitors

(2011) John S. Sack et al.   BIOCHEMICAL JOURNAL

Peptidic Partial Bisubstrates as Inhibitors of the Protein Arginine N-Methyltransferases

(2011) Peter 't Hart et al.   CHEMBIOCHEM

A Coactivator Role of CARM1 in the Dysregulation of  -Catenin Activity in Colorectal Cancer Cell Growth and Gene Expression

(2011) C.-Y. Ou et al.   MOLECULAR CANCER RESEARCH

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

(2011) Masoud Vedadi et al.   Nature Chemical Biology

Nη-Substituted Arginyl Peptide Inhibitors of Protein ArginineN-Methyltransferases

(2010) Ted M. Lakowski et al.   ACS Chemical Biology

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Differential CARM1 expression in prostate and colorectal cancers

(2010) Young-Rang Kim et al.   BMC CANCER

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL

Preparation ofNG-Substitutedl-Arginine Analogues Suitable for Solid Phase Peptide Synthesis

(2008) Nathaniel I. Martin et al.   JOURNAL OF ORGANIC CHEMISTRY

In Situ Generation of a Bisubstrate Analogue for Protein Arginine Methyltransferase 1

(2008) Tanesha Osborne et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY