Neuronal delivery of Hedgehog directs spatial patterning of taste organ regeneration

Notch signalling in context

(2016) Sarah J. Bray   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Understanding the impact of taste changes in oncology care

(2016) Joel B. Epstein et al.   SUPPORTIVE CARE IN CANCER

Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling

(2016) Alexandre N. Ermilov et al.   PLoS Genetics

Basal Cell Carcinoma Preferentially Arises from Stem Cells within Hair Follicle and Mechanosensory Niches

(2015) Shelby C. Peterson et al.   Cell Stem Cell

Hedgehog pathway blockade with the cancer drug LDE225 disrupts taste organs and taste sensation

(2015) Archana Kumari et al.   JOURNAL OF NEUROPHYSIOLOGY

Neural Hedgehog signaling maintains stem cell renewal in the sensory touch dome epithelium

(2015) Ying Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor

(2014) Hu Zhao et al.   Cell Stem Cell

A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors

(2014) J. Rodon et al.   CLINICAL CANCER RESEARCH

Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium

(2014) D. Castillo et al.   DEVELOPMENT

Sonic hedgehog-expressing basal cells are general post-mitotic precursors of functional taste receptor cells

(2014) Hirohito Miura et al.   DEVELOPMENTAL DYNAMICS

Clonal analysis reveals nerve-dependent and independent roles on mammalian hind limb tissue maintenance and regeneration

(2014) Yuval Rinkevich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stromal response to Hedgehog signaling restrains pancreatic cancer progression

(2014) J. J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vismodegib, an antagonist of hedgehog signaling, directly alters taste molecular signaling in taste buds

(2014) Hyekyung Yang et al.   Cancer Medicine

Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance

(2013) Hong Xiang. Liu et al.   DEVELOPMENTAL BIOLOGY

Functional Cell Types in Taste Buds Have Distinct Longevities

(2013) Isabel Perea-Martinez et al.   PLoS One

Abstract B192: Preclinical characterization of BMS-833923 (XL139), a hedgehog (HH) pathway inhibitor in early clinical development

(2012) S. B. Gendreau et al.   MOLECULAR CANCER THERAPEUTICS

Inhibiting the Hedgehog Pathway in Patients with the Basal-Cell Nevus Syndrome

(2012) Jean Y. Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma

(2012) Aleksandar Sekulic et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural Basis of Wnt Recognition by Frizzled

(2012) C. Y. Janda et al.   SCIENCE

Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells

(2011) Isaac Brownell et al.   Cell Stem Cell

Cyclophosphamide-induced disruption of umami taste functions and taste epithelium

(2011) N. Mukherjee et al.   NEUROSCIENCE

Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-  signaling

(2011) S. da Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potent agonists of the Hedgehog signaling pathway

(2009) Shirley A. Brunton et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Fate mapping of mammalian embryonic taste bud progenitors

(2009) S. Thirumangalathu et al.   DEVELOPMENT

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma

(2009) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Single-neuron labeling with inducible Cre-mediated knockout in transgenic mice

(2008) Paul Young et al.   NATURE NEUROSCIENCE

Cell Lineage Mapping of Taste Bud Cells and Keratinocytes in the Mouse Tongue and Soft Palate

(2008) Tadashi Okubo et al.   STEM CELLS