One-pot synthesis of reactive oxygen species (ROS)-self-immolative polyoxalate prodrug nanoparticles for hormone dependent cancer therapy with minimized side effects

Synthesis of PEGylated Ferrocene Nanoconjugates as the Radiosensitizer of Cancer Cells

(2016) Jian Tian et al.   BIOCONJUGATE CHEMISTRY

H2O2-triggered bubble generating antioxidant polymeric nanoparticles as ischemia/reperfusion targeted nanotheranostics

(2016) Changsun Kang et al.   BIOMATERIALS

Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical Studies

(2016) Karel Ulbrich et al.   CHEMICAL REVIEWS

Porous antioxidant polymer microparticles as therapeutic systems for the airway inflammatory diseases

(2016) Dahee Jeong et al.   JOURNAL OF CONTROLLED RELEASE

Fluorescent boronate-based polymer nanoparticles with reactive oxygen species (ROS)-triggered cargo release for drug-delivery applications

(2016) Eliézer Jäger et al.   Nanoscale

Soft Matter Assemblies as Nanomedicine Platforms for Cancer Chemotherapy: A Journey from Market Products Towards Novel Approaches

(2015) Eliézer Jäger et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Nanoparticles of the poly([N-(2-hydroxypropyl)]methacrylamide)-b-poly[2-(diisopropylamino)ethyl methacrylate] diblock copolymer for pH-triggered release of paclitaxel

(2015) Alessandro Jäger et al.   Polymer Chemistry

Hydrogen peroxide-activatable antioxidant prodrug as a targeted therapeutic agent for ischemia-reperfusion injury

(2015) Dongwon Lee et al.   Scientific Reports

Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles

(2014) Andrew G. Cheetham et al.   CHEMICAL COMMUNICATIONS

Cell-Penetrating Hyperbranched Polyprodrug Amphiphiles for Synergistic Reductive Milieu-Triggered Drug Release and Enhanced Magnetic Resonance Signals

(2014) Xianglong Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel poly(ethylene oxide monomethyl ether)-b-poly(ε-caprolactone) diblock copolymers containing a pH-acid labile ketal group as a block linkage

(2014) S. Petrova et al.   Polymer Chemistry

Development of a redox/pH dual stimuli-responsive MSP@P(MAA-Cy) drug delivery system for programmed release of anticancer drugs in tumour cells

(2014) Dian Li et al.   Journal of Materials Chemistry B

Polyprodrug Amphiphiles: Hierarchical Assemblies for Shape-Regulated Cellular Internalization, Trafficking, and Drug Delivery

(2013) Xianglong Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diethylstilboestrol for the treatment of prostate cancer: past, present and future

(2013) Rafal Turo et al.   Scandinavian Journal of Urology

Chemiluminescent and Antioxidant Micelles as Theranostic Agents for Hydrogen Peroxide Associated-Inflammatory Diseases

(2012) Sujin Cho et al.   ADVANCED FUNCTIONAL MATERIALS

Combination chemotherapy using core-shell nanoparticles through the self-assembly of HPMA-based copolymers and degradable polyester

(2012) Eliézer Jäger et al.   JOURNAL OF CONTROLLED RELEASE

Biocompatible Polymeric Nanoparticles Degrade and Release Cargo in Response to Biologically Relevant Levels of Hydrogen Peroxide

(2012) Caroline de Gracia Lux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Light scattering evidence of selective protein fouling on biocompatible block copolymer micelles

(2012) Fernando C. Giacomelli et al.   Nanoscale

Encapsulation and Enzyme-Mediated Release of Molecular Cargo in Polysulfide Nanoparticles

(2011) Brett L. Allen et al.   ACS Nano

Reduction of oxidative stress by p-hydroxybenzyl alcohol-containing biodegradable polyoxalate nanoparticulate antioxidant

(2011) Soojin Kim et al.   BIOMATERIALS

pH-Sensitive brush polymer-drug conjugates by ring-opening metathesis copolymerization

(2011) Jiong Zou et al.   CHEMICAL COMMUNICATIONS

Demonstrating the importance of polymer-conjugate conformation in solution on its therapeutic output: Diethylstilbestrol (DES)-polyacetals as prostate cancer treatment

(2011) Vanessa Giménez et al.   JOURNAL OF CONTROLLED RELEASE

Estrogen's Dual Nature? Studies Highlight Effects on Breast Cancer

(2011) R. Twombly   JNCI-Journal of the National Cancer Institute

Polyoxalate Nanoparticles as a Biodegradable and Biocompatible Drug Delivery Vehicle

(2010) Seho Kim et al.   BIOMACROMOLECULES

Antioxidant and Anti-Inflammatory Activities of Hydroxybenzyl Alcohol Releasing Biodegradable Polyoxalate Nanoparticles

(2010) Hyunjin Park et al.   BIOMACROMOLECULES

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

(2010) D. Scott Wilson et al.   NATURE MATERIALS

The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery

(2010) Dennis A. Smith et al.   NATURE REVIEWS DRUG DISCOVERY

Polyester-based micelles and nanoparticles for the parenteral delivery of taxanes

(2009) Geneviève Gaucher et al.   JOURNAL OF CONTROLLED RELEASE

Oxidative Stress Is Inherent in Prostate Cancer Cells and Is Required for Aggressive Phenotype

(2008) B. Kumar et al.   CANCER RESEARCH

Paclitaxel-loaded PEGylated PLGA-based nanoparticles: In vitro and in vivo evaluation

(2008) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE