Modelling the emergence of influenza drug resistance: The roles of surface proteins, the immune response and antiviral mechanisms
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Title
Modelling the emergence of influenza drug resistance: The roles of surface proteins, the immune response and antiviral mechanisms
Authors
Keywords
Antimicrobial resistance, Drug therapy, Adamantanes, Immune response, Virions, Microbial mutation, Influenza, Antivirals
Journal
PLoS One
Volume 12, Issue 7, Pages e0180582
Publisher
Public Library of Science (PLoS)
Online
2017-07-11
DOI
10.1371/journal.pone.0180582
References
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- (2016) Alessandro Boianelli et al. Frontiers in Cellular and Infection Microbiology
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- (2015) Yanyu Xiao et al. JOURNAL OF MATHEMATICAL BIOLOGY
- Quantifying relative within-host replication fitness in influenza virus competition experiments
- (2015) Stephen M. Petrie et al. JOURNAL OF THEORETICAL BIOLOGY
- Clinical Implications of Antiviral Resistance in Influenza
- (2015) Timothy Li et al. Viruses-Basel
- Impact of the H275Y and I223V Mutations in the Neuraminidase of the 2009 Pandemic Influenza Virus In Vitro and Evaluating Experimental Reproducibility
- (2015) Eric G. Paradis et al. PLoS One
- Impact of Different Oseltamivir Regimens on Treating Influenza A Virus Infection and Resistance Emergence: Insights from a Modelling Study
- (2014) Laetitia Canini et al. PLoS Computational Biology
- Estimating the Fitness Advantage Conferred by Permissive Neuraminidase Mutations in Recent Oseltamivir-Resistant A(H1N1)pdm09 Influenza Viruses
- (2014) Jeff Butler et al. PLoS Pathogens
- INTERGENERATIONAL PHENOTYPIC MIXING IN VIRAL EVOLUTION
- (2013) Claude Loverdo et al. EVOLUTION
- A model for the emergence of drug resistance in the presence of asymptomatic infections
- (2013) Marguerite Robinson et al. MATHEMATICAL BIOSCIENCES
- Assessing Mathematical Models of Influenza Infections Using Features of the Immune Response
- (2013) Hana M. Dobrovolny et al. PLoS One
- Model-Based Simulation and Prediction of an Antiviral Strategy against Influenza A Infection
- (2013) Kye-Yeon Hur et al. PLoS One
- The Timing and Targeting of Treatment in Influenza Pandemics Influences the Emergence of Resistance in Structured Populations
- (2013) Benjamin M. Althouse et al. PLoS Computational Biology
- Design and synthesis of pinanamine derivatives as anti-influenza A M2 ion channel inhibitors
- (2012) Xin Zhao et al. ANTIVIRAL RESEARCH
- INFLUENCE OF VIRAL REPLICATION MECHANISMS ON WITHIN-HOST EVOLUTIONARY DYNAMICS
- (2012) Claude Loverdo et al. EVOLUTION
- Combination Antiviral Therapy for Influenza: Predictions From Modeling of Human Infections
- (2012) Alan S. Perelson et al. JOURNAL OF INFECTIOUS DISEASES
- The H275Y Neuraminidase Mutation of the Pandemic A/H1N1 Influenza Virus Lengthens the Eclipse Phase and Reduces Viral Output of Infected Cells, Potentially Compromising Fitness in Ferrets
- (2012) L. T. Pinilla et al. JOURNAL OF VIROLOGY
- Comparable Fitness and Transmissibility between Oseltamivir-Resistant Pandemic 2009 and Seasonal H1N1 Influenza Viruses with the H275Y Neuraminidase Mutation
- (2012) D. D. Y. Wong et al. JOURNAL OF VIROLOGY
- Viral fitness: definitions, measurement, and current insights
- (2012) Andrew R Wargo et al. Current Opinion in Virology
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- (2012) Kasia A. Pawelek et al. PLoS Computational Biology
- Impact of Mutations at Residue I223 of the Neuraminidase Protein on the Resistance Profile, Replication Level, and Virulence of the 2009 Pandemic Influenza Virus
- (2011) Andrés Pizzorno et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Reduced airborne transmission of oseltamivir-resistant pandemic A/H1N1 virus in ferrets
- (2011) Marie-Eve Hamelin et al. ANTIVIRAL THERAPY
- The global spread of drug-resistant influenza
- (2011) D. L. Chao et al. Journal of the Royal Society Interface
- Assessing the In Vitro Fitness of an Oseltamivir-Resistant Seasonal A/H1N1 Influenza Strain Using a Mathematical Model
- (2011) Benjamin P. Holder et al. PLoS One
- Fitness of neuraminidase inhibitor-resistant influenza A viruses
- (2011) Tatiana Baranovich et al. Current Opinion in Virology
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- (2010) A. N. Brown et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Pandemic H1N1 2009 influenza virus with the H275Y oseltamivir resistance neuraminidase mutation shows a small compromise in enzyme activity and viral fitness
- (2010) D. W. Brookes et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Genetic Makeup of Amantadine-Resistant and Oseltamivir-Resistant Human Influenza A/H1N1 Viruses
- (2010) H. Zaraket et al. JOURNAL OF CLINICAL MICROBIOLOGY
- The I222V Neuraminidase Mutation Has a Compensatory Role in Replication of an Oseltamivir-Resistant Influenza Virus A/H3N2 E119V Mutant
- (2010) P. Simon et al. JOURNAL OF CLINICAL MICROBIOLOGY
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- (2008) Catherine A.A. Beauchemin et al. JOURNAL OF THEORETICAL BIOLOGY
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- Management of drug resistance in the population: influenza as a case study
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