Antimicrobial peptides extend lifespan in Drosophila

Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction

(2016) Jennifer C Regan et al.   eLife

Intestinal FoxO signaling is required to survive oral infection in Drosophila

(2015) C Fink et al.   Mucosal Immunology

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality

(2015) Rebecca I. Clark et al.   Cell Reports

PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan

(2014) Linlin Guo et al.   CELL

Forkhead, a new cross regulator of metabolism and innate immunity downstream of TOR in Drosophila

(2014) Disha Varma et al.   JOURNAL OF INSECT PHYSIOLOGY

Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology

(2014) N. A. Broderick et al.   mBio

Melanotic Pathology and Vertical Transmission of the Gut Commensal Elizabethkingia meningoseptica in the Major Malaria Vector Anopheles gambiae

(2013) Idir G. Akhouayri et al.   PLoS One

big bang gene modulates gut immune tolerance in Drosophila

(2013) F. Bonnay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organ-specific mediation of lifespan extension: More than a gut feeling?

(2012) Michael Rera et al.   AGEING RESEARCH REVIEWS

Impact of the Resident Microbiota on the Nutritional Phenotype of Drosophila melanogaster

(2012) Emma V. Ridley et al.   PLoS One

Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila

(2012) M. Rera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

dFOXO-independent effects of reduced insulin-like signaling inDrosophila

(2011) Cathy Slack et al.   AGING CELL

Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection

(2011) Nicolas Buchon et al.   BMC BIOLOGY

Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog

(2011) Michael Rera et al.   Cell Metabolism

Comparative pathology of bacteria in the genus Providencia to a natural host, Drosophila melanogaster

(2011) Madeline R. Galac et al.   MICROBES AND INFECTION

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

(2011) Charles L. Bevins et al.   NATURE REVIEWS MICROBIOLOGY

Increased transsulfuration mediates longevity and dietary restriction in Drosophila

(2011) H. Kabil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural roles of antimicrobial peptides in microbes, plants and animals

(2011) Gergely Maróti et al.   RESEARCH IN MICROBIOLOGY

Bacterial Communities of Diverse Drosophila Species: Ecological Context of a Host–Microbe Model System

(2011) James Angus Chandler et al.   PLoS Genetics

EGFR/Ras/MAPK Signaling Mediates Adult Midgut Epithelial Homeostasis and Regeneration in Drosophila

(2010) Huaqi Jiang et al.   Cell Stem Cell

Antimicrobial peptides: General overview and clinical implications in human health and disease

(2010) Eduardo Guaní-Guerra et al.   CLINICAL IMMUNOLOGY

Antimicrobial Peptides Increase Tolerance to Oxidant Stress inDrosophila melanogaster

(2010) Huiwen W. Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FOXO-dependent regulation of innate immune homeostasis

(2010) Thomas Becker et al.   NATURE

Lifespan Extension by Preserving Proliferative Homeostasis in Drosophila

(2010) Benoît Biteau et al.   PLoS Genetics

Antimicrobial Peptides: Primeval Molecules or Future Drugs?

(2010) Brian M. Peters et al.   PLoS Pathogens

Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

(2009) Huaqi Jiang et al.   CELL

Drosophila Intestinal Response to Bacterial Infection: Activation of Host Defense and Stem Cell Proliferation

(2009) Nicolas Buchon et al.   Cell Host & Microbe

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

(2009) N. Buchon et al.   GENES & DEVELOPMENT

Characterization of theDrosophilaGene-Switch system in aging studies: a cautionary tale

(2008) Luc Poirier et al.   AGING CELL

PIMS Modulates Immune Tolerance by Negatively Regulating Drosophila Innate Immune Signaling

(2008) Nouara Lhocine et al.   Cell Host & Microbe

JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut

(2008) Benoît Biteau et al.   Cell Stem Cell

Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in Drosophila

(2008) J.-H. Ryu et al.   SCIENCE

Antimicrobial peptides of the Cecropin-family show potent antitumor activity against bladder cancer cells

(2008) Henrik Suttmann et al.   BMC Urology