Deletion of Shp2 in bronchial epithelial cells impairs IL-25 production in vitro, but has minor influence on asthmatic inflammation in vivo

Eosinophil differentiation in the bone marrow is promoted by protein tyrosine phosphatase SHP2

(2016) L-x Xia et al.   Cell Death & Disease

Dynamic role of epithelium-derived cytokines in asthma

(2012) Kathleen R. Bartemes et al.   CLINICAL IMMUNOLOGY

Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis

(2012) Xue Zhang et al.   FASEB JOURNAL

Epithelial Cell-Derived IL-25, but Not Th17 Cell-Derived IL-17 or IL-17F, Is Crucial for Murine Asthma

(2012) M. Suzukawa et al.   JOURNAL OF IMMUNOLOGY

Shp2 Plays an Important Role in Acute Cigarette Smoke-Mediated Lung Inflammation

(2012) F.-f. Li et al.   JOURNAL OF IMMUNOLOGY

The airway epithelium in asthma

(2012) Bart N Lambrecht et al.   NATURE MEDICINE

Alternaria-Induced Release of IL-18 from Damaged Airway Epithelial Cells: An NF-κB Dependent Mechanism of Th2 Differentiation?

(2012) Hiroki Murai et al.   PLoS One

Positive and negative regulation of the Drosophila immune response

(2011) Kamna Aggarwal et al.   BMB Reports

Inflammatory dendritic cells—not basophils—are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen

(2010) Hamida Hammad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites

(2009) Steven A. Saenz et al.   IMMUNOLOGICAL REVIEWS

JAK2 and SHP2 Reciprocally Regulate Tyrosine Phosphorylation and Stability of Proapoptotic Protein ASK1

(2009) Luyang Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

(2009) Hamida Hammad et al.   NATURE MEDICINE

Treatment with anti-CC chemokine receptor 3 monoclonal antibody or dexamethasone inhibits the migration and differentiation of bone marrow CD34+progenitor cells in an allergic mouse model

(2008) S. Ben et al.   ALLERGY

rtTA toxicity limits the usefulness of the SP-C-rtTA transgenic mouse

(2008) Mitsuru Morimoto et al.   DEVELOPMENTAL BIOLOGY

Protein tyrosine phosphatases in the JAK/STAT pathway

(2008) Dan Xu   Frontiers in Bioscience-Landmark