HLA-DR7 and HLA-DQ2: Transgenic mouse strains tested as a model system for ximelagatran hepatotoxicity

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Treatment of PD-1−/−mice with amodiaquine and anti-CTLA4 leads to liver injury similar to idiosyncratic liver injury in patients

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Drug-induced allergic hepatitis develops in mice when myeloid-derived suppressor cells are depleted prior to halothane treatment

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Genetics of Immune-Mediated Adverse Drug Reactions: a Comprehensive and Clinical Review

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Genotyping for Severe Drug Hypersensitivity

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Lapatinib-Induced Liver Injury Characterized by Class II HLA and Gilbert's Syndrome Genotypes

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High mobility group box chromosomal protein 1 in acute-on-chronic liver failure patients and mice with ConA-induced acute liver injury

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Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury

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Pharmacogenomics in clinical practice and drug development

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HLA and pharmacogenetics of drug hypersensitivity

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Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

(2012) D. A. Ostrov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers

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Drug Hypersensitivity and Human Leukocyte Antigens of the Major Histocompatibility Complex

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Role of HLA class II genes in susceptibility and resistance to multiple sclerosis: Studies using HLA transgenic mice

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A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

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Bidirectional binding of invariant chain peptides to an MHC class II molecule

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A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran

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Role of HLA class II genes in susceptibility/resistance to inflammatory arthritis: studies with humanized mice

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HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

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Genetic Association Studies in Drug-Induced Liver Injury

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High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo

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Abacavir Hypersensitivity Reaction: an Update

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Prediction of drug-induced liver injury in humans by using in vitro methods: The case of ximelagatran

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