A mutant of phosphomannomutase1 retains full enzymatic activity, but is not activated by IMP: Possible implications for the disease PMM2-CDG

Looking for protein stabilizing drugs with thermal shift assay

(2015) Giuseppina Andreotti et al.   Drug Testing and Analysis

The Effects of PMM2-CDG-Causing Mutations on the Folding, Activity, and Stability of the PMM2 Protein

(2015) Patricia Yuste-Checa et al.   HUMAN MUTATION

Drug repositioning can accelerate discovery of pharmacological chaperones

(2015) Bruno Hay Mele et al.   Orphanet Journal of Rare Diseases

Heterodimerization of Two Pathological Mutants Enhances the Activity of Human Phosphomannomutase2

(2015) Giuseppina Andreotti et al.   PLoS One

Conformational Response to Ligand Binding in Phosphomannomutase2

(2014) Giuseppina Andreotti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-linked protein glycosylation in the ER

(2013) Markus Aebi   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Identification and analysis of conserved pockets on protein surfaces

(2013) Marco Cammisa et al.   BMC BIOINFORMATICS

Monte Carlo Free Ligand Diffusion with Markov State Model Analysis and Absolute Binding Free Energy Calculations

(2013) Ryoji Takahashi et al.   Journal of Chemical Theory and Computation

PELE web server: atomistic study of biomolecular systems at your fingertips

(2013) Armin Madadkar-Sobhani et al.   NUCLEIC ACIDS RESEARCH

Biochemical phenotype of a common disease-causing mutation and a possible therapeutic approach for the phosphomannomutase 2-associated disorder of glycosylation

(2013) Giuseppina Andreotti et al.   Molecular Genetics & Genomic Medicine

Phosphomannose Isomerase Inhibitors ImproveN-Glycosylation in Selected Phosphomannomutase-deficient Fibroblasts

(2011) Vandana Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

Evolutionary History and Functional Diversification of Phosphomannomutase Genes

(2010) Rita Quental et al.   JOURNAL OF MOLECULAR EVOLUTION

Dolichol-phosphate mannose synthase: Structure, function and regulation

(2008) Yusuke Maeda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mammalian Phosphomannomutase PMM1 Is the Brain IMP-sensitive Glucose-1,6-bisphosphatase

(2008) Maria Veiga-da-Cunha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

On the nomenclature of congenital disorders of glycosylation (CDG)

(2008) J. Jaeken et al.   JOURNAL OF INHERITED METABOLIC DISEASE