Matrine Suppresses the ER-positive MCF Cells by Regulating Energy Metabolism and Endoplasmic Reticulum Stress Signaling Pathway

A phase II trial of bendamustine in combination with rituximab in older patients with previously untreated diffuse large B-cell lymphoma

(2016) Steven I. Park et al.   BRITISH JOURNAL OF HAEMATOLOGY

Toll-like receptor 4 ablation rescues against paraquat-triggered myocardial dysfunction: Role of ER stress and apoptosis

(2016) Yonghong Lei et al.   ENVIRONMENTAL TOXICOLOGY

Three components of cigarette smoke altered the growth and apoptosis of metastatic colon cancer cells via inducing the synthesis of reactive oxygen species and endoplasmic reticulum stress

(2016) Hae-Miru Lee et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Tunicamycin-induced endoplasmic reticulum stress reduces in vitro subpopulation and invasion of CD44+/CD24- phenotype breast cancer stem cells

(2016) Babak Nami et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population

(2016) Kayleen Vannuvel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Oocyte activation and latent HIV-1 reactivation: AMPK as a common mechanism of action linking the beginnings of life and the potential eradication of HIV-1

(2016) Jahahreeh Finley   MEDICAL HYPOTHESES

Androgen deprivation leads to increased carbohydrate metabolism and hexokinase 2-mediated survival in Pten/Tp53-deficient prostate cancer

(2016) P L Martin et al.   ONCOGENE

A Critical Approach to Evaluating Clinical Efficacy, Adverse Events and Drug Interactions of Herbal Remedies

(2016) Angelo A. Izzo et al.   PHYTOTHERAPY RESEARCH

Natural Products as Mechanism-based Anticancer Agents: Sp Transcription Factors as Targets

(2016) Stephen Safe et al.   PHYTOTHERAPY RESEARCH

MiRNAs-mediated cisplatin resistance in breast cancer

(2016) Xiu Chen et al.   TUMOR BIOLOGY

Synergistic increase in efficacy of a combination of 2-deoxy-d-glucose and cisplatin in normoxia and hypoxia: switch from autophagy to apoptosis

(2016) Akansha Jalota et al.   TUMOR BIOLOGY

Breast cancer epidemic in the early twenty-first century: evaluation of risk factors, cumulative questionnaires and recommendations for preventive measures

(2016) Olga Golubnitschaja et al.   TUMOR BIOLOGY

Endoplasmic reticulum stress, unfolded protein response and development of colon adenocarcinoma

(2016) Nicolas Piton et al.   VIRCHOWS ARCHIV

Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner

(2016) Consuelo Amantini et al.   Oncotarget

Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release

(2016) Chenghui Liao et al.   Oncotarget

Endothelin‐1 Drives Epithelial‐Mesenchymal Transition in Hypertensive Nephroangiosclerosis

(2016) Teresa M. Seccia et al.   Journal of the American Heart Association

The Therapeutic Efficacy and Safety of Compound Kushen Injection Combined with Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma: An Update Systematic Review and Meta-Analysis

(2016) Xiao Ma et al.   Frontiers in Pharmacology

PI3K/Akt signaling mediated Hexokinase-2 expression inhibits cell apoptosis and promotes tumor growth in pediatric osteosarcoma

(2015) Baobiao Zhuo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

JNK-Bcl-2/Bcl-xL-Bax/Bak Pathway Mediates the Crosstalk between Matrine-Induced Autophagy and Apoptosis via Interplay with Beclin 1

(2015) Jiong Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Review: Phytochemicals Targeting JAK/STAT Signaling and IDO Expression in Cancer

(2015) Niroshaathevi Arumuggam et al.   PHYTOTHERAPY RESEARCH

Matrine-Induced Apoptosis of Human Nasopharyngeal Carcinoma Cells via In Vitro Vascular Endothelial Growth Factor-A/Extracellular Signal-Regulated Kinase1/2 Pathway Inactivation

(2014) M. Xie et al.   HORMONE AND METABOLIC RESEARCH

Akt inhibition promotes hexokinase 2 redistribution and glucose uptake in cancer cells

(2013) Catherine L. Neary et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Matrine, a novel autophagy inhibitor, blocks trafficking and the proteolytic activation of lysosomal proteases

(2012) Z. Wang et al.   CARCINOGENESIS

Matrine Inhibits Breast Cancer Growth ViamiR-21/PTEN/AktPathway in MCF-7 Cells

(2012) Lin-Qiang Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Choline Kinase Alpha and Hexokinase-2 Protein Expression in Hepatocellular Carcinoma: Association with Survival

(2012) Sandi A. Kwee et al.   PLoS One

Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis

(2011) Ying-Hong Shi et al.   Autophagy

Overexpression of GRP78 protects glial cells from endoplasmic reticulum stress

(2011) Kaori Suyama et al.   NEUROSCIENCE LETTERS

Therapeutic Effects of Matrine on Primary and Metastatic Breast Cancer

(2010) Hali Li et al.   AMERICAN JOURNAL OF CHINESE MEDICINE