Matrine, a novel autophagy inhibitor, blocks trafficking and the proteolytic activation of lysosomal proteases

Proteases in autophagy

(2011) Vitaliy Kaminskyy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Pancreatic cancers require autophagy for tumor growth

(2011) S. Yang et al.   GENES & DEVELOPMENT

The dynamic nature of autophagy in cancer

(2011) A. C. Kimmelman   GENES & DEVELOPMENT

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

The Role of Autophagy in Cancer: Therapeutic Implications

(2011) Z. J. Yang et al.   MOLECULAR CANCER THERAPEUTICS

Therapeutic Effects of Matrine on Primary and Metastatic Breast Cancer

(2010) Hali Li et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Autophagic degradation of active caspase-8

(2010) Wen Hou et al.   Autophagy

Matrine Inhibits Proliferation and Induces Apoptosis of Pancreatic Cancer Cells in Vitro and in Vivo

(2010) Tianyou Liu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Effects of matrine on HepG2 cell proliferation and expression of tumor relevant proteinsin vitro

(2010) Xue-Gong Qin et al.   PHARMACEUTICAL BIOLOGY

Antitumor effect of matrine in human hepatoma G2 cells by inducing apoptosis and autophagy

(2010) Jun-Qiang Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

Antiarrhythmic Properties of Long-Term Treatment with Matrine in Arrhythmic Rat Induced by Coronary Ligation

(2009) Xuelian Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Sophocarpine and matrine inhibit the production of TNF-α and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice

(2008) Yuefan Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Abl Kinases Regulate Autophagy by Promoting the Trafficking and Function of Lysosomal Components

(2008) Gouri Yogalingam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrine induces programmed cell death and regulates expression of relevant genes based on PCR array analysis in C6 glioma cells

(2008) Shujun Zhang et al.   MOLECULAR BIOLOGY REPORTS

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Ocular Toxicity of Hydroxychloroquine

(2008) Rodney Tehrani et al.   Seminars in Ophthalmology