Bufadienolides of Kalanchoe species: an overview of chemical structure, biological activity and prospects for pharmacological use

Bufadienolides from Kalanchoe daigremontiana as thrombin inhibitors— In vitro and in silico study

(2017) Joanna Kolodziejczyk-Czepas et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Potential of Bryophyllum pinnatum as a Detrusor Relaxant: An in Vitro Exploratory Study

(2017) Simon Bachmann et al.   PLANTA MEDICA

Evaluation of Bufadienolides as the Main Antitumor Components in Cinobufacin Injection for Liver and Gastric Cancer Therapy

(2017) Xiaolu Wei et al.   PLoS One

Metabolites profiling of 10 bufadienolides in human liver microsomes and their cytotoxicity variation in HepG2 cell

(2016) Lingyu Han et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

New Bufadienolides Isolated from the Roots of Kalanchoe daigremontiana (Crassulaceae)

(2016) Barbara Moniuszko-Szajwaj et al.   MOLECULES

Potential Health Risks Posed by Plant-Derived Cumulative Neurotoxic Bufadienolides in South Africa

(2016) Christo Botha   MOLECULES

Effects of active bufadienolide compounds on human cancer cells and CD4+CD25+Foxp3+ regulatory T cells in mitogen-activated human peripheral blood mononuclear cells

(2016) Bo Yuan et al.   ONCOLOGY REPORTS

Antioxidant efficacy of Kalanchoe daigremontiana bufadienolide-rich fraction in blood plasma in vitro

(2016) Joanna Kolodziejczyk-Czepas et al.   PHARMACEUTICAL BIOLOGY

Ethnobotanical survey of medicinal plant species used by communities around Mabira Central Forest Reserve, Uganda

(2016) Patience Tugume et al.   Journal of Ethnobiology and Ethnomedicine

Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer

(2016) Liyuan Zhang et al.   Oncotarget

First serine protease inhibitor isolated from Rhinella schneideri poison

(2015) Priscila Y T Shibao et al.   JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES

Ethnomedicinal survey of various communities residing in Garo Hills of Durgapur, Bangladesh

(2015) Md. Arif Khan et al.   Journal of Ethnobiology and Ethnomedicine

Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway

(2015) Ning Tang et al.   Oncotarget

Molecular Structure-Affinity Relationship of Bufadienolides and Human Serum Albumin In Vitro and Molecular Docking Analysis

(2015) Jing Zhou et al.   PLoS One

Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt

(2014) Li-Juan Deng et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells

(2014) Zhenlong Yu et al.   Molecular Cancer

A study of the medicinal plants used by the Marakwet Community in Kenya

(2014) Wilson Kipkore et al.   Journal of Ethnobiology and Ethnomedicine

Ethnomedicinal plants used to treat human ailments in the prehistoric place of Harla and Dengego valleys, eastern Ethiopia

(2014) Anteneh Belayneh et al.   Journal of Ethnobiology and Ethnomedicine

The Lipophilic Bullet Hits the Targets: Medicinal Chemistry of Adamantane Derivatives

(2013) Lukas Wanka et al.   CHEMICAL REVIEWS

Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase

(2013) Laetitia Moreno Y Banuls et al.   Molecular Cancer

Cardenolides and Bufadienolide Glycosides from Kalanchoe tubiflora and Evaluation of Cytotoxicity

(2013) Hui-Chi Huang et al.   PLANTA MEDICA

Bufalin, a Traditional Oriental Medicine, Induces Apoptosis in Human Cancer Cells

(2012) Noriyuki Takai et al.   Asian Pacific Journal of Cancer Prevention

Kalanchoe tubiflora extract inhibits cell proliferation by affecting the mitotic apparatus

(2012) Yi-Jen Hsieh et al.   BMC Complementary and Alternative Medicine

Adverse Drug Reactions in a Complementary Medicine Hospital: A Prospective, Intensified Surveillance Study

(2012) M. Süsskind et al.   Evidence-based Complementary and Alternative Medicine

Improved antitumor efficacy and reduced toxicity of liposomes containing bufadienolides

(2011) Kaili Hu et al.   ARCHIVES OF PHARMACAL RESEARCH

Traditional plants used for medicinal purposes by local communities around the Northern sector of Kibale National Park, Uganda

(2011) Jane Namukobe et al.   JOURNAL OF ETHNOPHARMACOLOGY

Bufadienolides and their antitumor activity

(2011) Huimin Gao et al.   NATURAL PRODUCT REPORTS

Analgesic and Anti-Inflammatory Activities of the Methanol Extract of Kalanchoe gracilis (L.) DC Stem in Mice

(2010) Zhen-Rung Lai et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Emerging Role of the Bufadienolides in Cardiovascular and Kidney Diseases

(2010) Jules B. Puschett et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Bioactive molecules in Kalanchoe pinnata leaves: extraction, purification, and identification

(2010) Saïda El Abdellaoui et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Cytotoxic principles and α-pyrone ring-opening derivatives of bufadienolides from Kalanchoe hybrida

(2008) Ping-Chung Kuo et al.   TETRAHEDRON