Genetics of hypertension: an assessment of progress in the spontaneously hypertensive rat

Rare and low-frequency coding variants alter human adult height

(2017) Eirini Marouli et al.   NATURE

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

(2017) Helen R Warren et al.   NATURE GENETICS

Genetic regulatory signatures underlying islet gene expression and type 2 diabetes

(2017) Arushi Varshney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Incomplete Understanding of Human Genetic Variation

(2016) J. Huddleston et al.   GENETICS

Common Polymorphisms at theCYP17A1Locus Associate With Steroid PhenotypeNovelty and Significance

(2016) Louise A. Diver et al.   HYPERTENSION

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

(2016) Georg B Ehret et al.   NATURE GENETICS

Genomic landscape of rat strain and substrain variation

(2015) Roel Hermsen et al.   BMC GENOMICS

Dissecting the genetics of the human transcriptome identifies novel trait-relatedtrans-eQTLs and corroborates the regulatory relevance of non-protein coding loci

(2015) Holger Kirsten et al.   HUMAN MOLECULAR GENETICS

Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation

(2015) Damien C. Croteau-Chonka et al.   PLoS One

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

(2014) Alexander Gusev et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Rat Genome Database 2015: genomic, phenotypic and environmental variations and disease

(2014) Mary Shimoyama et al.   NUCLEIC ACIDS RESEARCH

Analysis of Sry duplications on the Rattus norvegicus Y-chromosome

(2013) Jeremy W Prokop et al.   BMC GENOMICS

Genome Sequencing Reveals Loci under Artificial Selection that Underlie Disease Phenotypes in the Laboratory Rat

(2013) Santosh S. Atanur et al.   CELL

Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases

(2013) Gosia Trynka et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Loci influencing blood pressure identified using a cardiovascular gene-centric array

(2013) Santhi K. Ganesh, Vinicius Tragante, Wei Guo, Yiran Guo, Matthew B. Lanktree, Erin N. Smith, Toby Johnson, Berta Almoguera Castillo, John Barnard, Jens Baumert, Yen-Pei Christy Chang, Clara C. Elbers, Martin Farrall, Mary E. Fischer, Nora Franceschini, Tom R. Gaunt, Johannes M.I.H. Gho, Christian Gieger, Yan Gong, Aaron Isaacs, Marcus E. Kleber, Irene Mateo Leach, Caitrin W. McDonough, Matthijs F.L. Meijs, Olle Mellander, Cliona M. Molony, Ilja M. Nolte, Sandosh Padmanabhan, Tom S. Price, Ramakrishnan Rajagopalan, Jonathan Shaffer, Sonia Shah, Haiqing Shen, Nicole Soranzo, Peter J. van der Most, Erik P.A. Van Iperen, Jessic A. Van Setten, Judith M. Vonk, Li Zhang, Amber L. Beitelshees, Gerald S. Berenson, Deepak L. Bhatt, Jolanda M.A. Boer, Eric Boerwinkle, Ben Burkley, Amber Burt, Aravinda Chakravarti, Wei Chen, Rhonda M. Cooper-DeHoff, Sean P. Curtis, Albert Dreisbach, David Duggan, Georg B. Ehret, Richard R. Fabsitz, Myriam Fornage, Ervin Fox, Clement E. Furlong, Ron T. Gansevoort, Marten H. Hofker, G. Kees Hovingh, Susan A. Kirkland, Kandice Kottke-Marchant, Abdullah Kutlar, Andrea Z. LaCroix, Taimour Y. Langaee, Yun R. Li, Honghuang Lin, Kiang Liu, Steffi Maiwald, Rainer Malik, Gurunathan Murugesan, Christopher Newton-Cheh, Jeffery R. O'Connell, N. Charlotte Onland-Moret, Willem H. Ouwehand et al.   HUMAN MOLECULAR GENETICS

Hypertensive renal disease

(2013) Michael C. Braun et al.   JOURNAL OF HYPERTENSION

Transgenic rescue of defective Cd36 enhances myocardial adenylyl cyclase signaling in spontaneously hypertensive rats

(2013) Martina Klevstig et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Quantitative and Qualitative Proteome Characteristics Extracted from In-Depth Integrated Genomics and Proteomics Analysis

(2013) Teck Yew Low et al.   Cell Reports

High-Resolution Identity by Descent Mapping Uncovers the Genetic Basis for Blood Pressure Differences Between Spontaneously Hypertensive Rat Lines

(2011) Rebecca Bell et al.   Circulation-Cardiovascular Genetics

The Sry3 Y Chromosome Locus Elevates Blood Pressure and Renin-Angiotensin System Indexes

(2011) Daniel Ely et al.   Gender Medicine

The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance

(2010) S. S. Atanur et al.   GENOME RESEARCH

Meta-Analysis of Genome-Wide Gene Expression Differences in Onset and Maintenance Phases of Genetic Hypertension

(2010) Francine Z. Marques et al.   HYPERTENSION

Variants in the CD36 Gene Locus Determine Whole-Body Adiposity, but Have No Independent Effect on Insulin Sensitivity

(2010) Martin Heni et al.   Obesity

Genome-Wide Identification of Allelic Expression in Hypertensive Rats

(2009) Renata I. Dmitrieva et al.   Circulation-Cardiovascular Genetics

Genome-wide association study identifies eight loci associated with blood pressure

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Genome-wide association study of blood pressure and hypertension

(2009) Daniel Levy et al.   NATURE GENETICS

Mapping complex disease traits with global gene expression

(2009) William Cookson et al.   NATURE REVIEWS GENETICS

Which Sry Locus Is the Hypertensive Y Chromosome Locus?

(2008) Monte E. Turner et al.   HYPERTENSION

Hemodynamic Characterization of Recombinant Inbred Strains: Twenty Years Later

(2008) Jaroslav KUNES et al.   HYPERTENSION RESEARCH

FAT/CD36 expression is not ablated in spontaneously hypertensive rats

(2008) Arend Bonen et al.   JOURNAL OF LIPID RESEARCH

Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension

(2008) Michal Pravenec et al.   NATURE GENETICS

SNP and haplotype mapping for genetic analysis in the rat

(2008) Kathrin Saar et al.   NATURE GENETICS

Rats in the genomic era

(2007) K. C. Worley et al.   PHYSIOLOGICAL GENOMICS