Single-molecule nanopore enzymology

DNA Translocation through Nanopores at Physiological Ionic Strengths Requires Precise Nanoscale Engineering

(2016) Lorenzo Franceschini et al.   ACS Nano

Semisynthetic Nanoreactor for Reversible Single-Molecule Covalent Chemistry

(2016) Joongoo Lee et al.   ACS Nano

Alpha-Helical Fragaceatoxin C Nanopore Engineered for Double-Stranded and Single-Stranded Nucleic Acid Analysis

(2016) Carsten Wloka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biomimetic Hybrid Nanocontainers with Selective Permeability

(2016) Lea Messager et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Man-made molecular machines: membrane bound

(2016) Matthew A. Watson et al.   CHEMICAL SOCIETY REVIEWS

Engineered transmembrane pores

(2016) Mariam Ayub et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Modulation of DNA Polymerase Noncovalent Kinetic Transitions by Divalent Cations

(2016) Joseph M. Dahl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Real-time shape approximation and fingerprinting of single proteins using a nanopore

(2016) Erik C. Yusko et al.   Nature Nanotechnology

Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process

(2016) Ioan Iacovache et al.   Nature Communications

Acidity-Mediated, Electrostatic Tuning of Asymmetrically Charged Peptides Interactions with Protein Nanopores

(2015) Alina Asandei et al.   ACS Applied Materials & Interfaces

Direct and Scalable Deposition of Atomically Thin Low-Noise MoS2 Membranes on Apertures

(2015) Pradeep Waduge et al.   ACS Nano

Pim Kinase Inhibitors Evaluated with a Single-Molecule Engineered Nanopore Sensor

(2015) Leon Harrington et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Proximal Capture Dynamics for a Single Biological Nanopore Sensor

(2015) Emmanuel D. Pederson et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Single-Molecule Analyte Recognition with ClyA Nanopores Equipped with Internal Protein Adaptors

(2015) Misha Soskine et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Protein Rotaxane Controls the Translocation of Proteins Across a ClyA Nanopore

(2015) Annemie Biesemans et al.   NANO LETTERS

Electrochemical Reaction in Single Layer MoS2: Nanopores Opened Atom by Atom

(2015) J. Feng et al.   NANO LETTERS

DNA stretching and optimization of nucleobase recognition in enzymatic nanopore sequencing

(2015) David Stoddart et al.   NANOTECHNOLOGY

Subangstrom single-molecule measurements of motor proteins using a nanopore

(2015) Ian M Derrington et al.   NATURE BIOTECHNOLOGY

Identification of single nucleotides in MoS2 nanopores

(2015) Jiandong Feng et al.   Nature Nanotechnology

Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

(2015) Koji Tanaka et al.   Nature Communications

Placement of oppositely charged aminoacids at a polypeptide termini determines the voltage-controlled braking of polymer transport through nanometer-scale pores

(2015) Alina Asandei et al.   Scientific Reports

Engineering a nanopore with co-chaperonin function

(2015) C.-W. Ho et al.   Science Advances

Atomically Thin Molybdenum Disulfide Nanopores with High Sensitivity for DNA Translocation

(2014) Ke Liu et al.   ACS Nano

Detection of Two Isomeric Binding Configurations in a Protein–Aptamer Complex with a Biological Nanopore

(2014) Veerle Van Meervelt et al.   ACS Nano

Discrimination among Protein Variants Using an Unfoldase-Coupled Nanopore

(2014) Jeff Nivala et al.   ACS Nano

High-Bandwidth Protein Analysis Using Solid-State Nanopores

(2014) Joseph Larkin et al.   BIOPHYSICAL JOURNAL

Communication: Charge, diffusion, and mobility of proteins through nanopores

(2014) M. Muthukumar   JOURNAL OF CHEMICAL PHYSICS

Probing Water Density and Dynamics in the Chaperonin GroEL Cavity

(2014) John M. Franck et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA origami nanopores: developments, challenges and perspectives

(2014) Silvia Hernández-Ainsa et al.   Nanoscale

De novo design of a transmembrane Zn2+-transporting four-helix bundle

(2014) Nathan H. Joh et al.   SCIENCE

Computational design of water-soluble α-helical barrels

(2014) Andrew R. Thomson et al.   SCIENCE

Single Protein Molecule Detection by Glass Nanopores

(2013) Wenhong Li et al.   ACS Nano

DNA Origami Nanopores for Controlling DNA Translocation

(2013) Silvia Hernández-Ainsa et al.   ACS Nano

Single-Molecule Studies of Intrinsically Disordered Proteins Using Solid-State Nanopores

(2013) Deanpen Japrung et al.   ANALYTICAL CHEMISTRY

Functional understanding of solvent structure in GroEL cavity through dipole field analysis

(2013) Jeffrey K. Weber et al.   JOURNAL OF CHEMICAL PHYSICS

Kinetic Mechanism of Translocation and dNTP Binding in Individual DNA Polymerase Complexes

(2013) Kate R. Lieberman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tuning the Size and Properties of ClyA Nanopores Assisted by Directed Evolution

(2013) Misha Soskine et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembled DNA Nanopores That Span Lipid Bilayers

(2013) Jonathan R. Burns et al.   NANO LETTERS

Fast Translocation of Proteins through Solid State Nanopores

(2013) Calin Plesa et al.   NANO LETTERS

Unfoldase-mediated protein translocation through an α-hemolysin nanopore

(2013) Jeff Nivala et al.   NATURE BIOTECHNOLOGY

A nanopore machine promotes the vectorial transport of DNA across membranes

(2013) Lorenzo Franceschini et al.   Nature Communications

Ultrashort single-walled carbon nanotubes in a lipid bilayer as a new nanopore sensor

(2013) Lei Liu et al.   Nature Communications

Diameter-dependent ion transport through the interior of isolated single-walled carbon nanotubes

(2013) Wonjoon Choi et al.   Nature Communications

Sensing Proteins through Nanopores: Fundamental to Applications

(2012) Abdelghani Oukhaled et al.   ACS Chemical Biology

DNA Origami Gatekeepers for Solid-State Nanopores

(2012) Ruoshan Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamics of the Translocation Step Measured in Individual DNA Polymerase Complexes

(2012) Kate R. Lieberman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering a Rigid Protein Tunnel for Biomolecular Detection

(2012) Mohammad M. Mohammad et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Engineered ClyA Nanopore Detects Folded Target Proteins by Selective External Association and Pore Entry

(2012) Misha Soskine et al.   NANO LETTERS

Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase

(2012) Elizabeth A Manrao et al.   NATURE BIOTECHNOLOGY

Automated forward and reverse ratcheting of DNA in a nanopore at 5-Å precision

(2012) Gerald M Cherf et al.   NATURE BIOTECHNOLOGY

Stochastic sensing of proteins with receptor-modified solid-state nanopores

(2012) Ruoshan Wei et al.   Nature Nanotechnology

Revisiting the contribution of negative charges on the chaperonin cage wall to the acceleration of protein folding

(2012) F. Motojima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Lipid Membrane Channels Formed by Designed DNA Nanostructures

(2012) M. Langecker et al.   SCIENCE

Dynamics of Completely Unfolded and Native Proteins through Solid-State Nanopores as a Function of Electric Driving Force

(2011) Abdelghani Oukhaled et al.   ACS Nano

Stacked Graphene-Al2O3 Nanopore Sensors for Sensitive Detection of DNA and DNA–Protein Complexes

(2011) Bala Murali Venkatesan et al.   ACS Nano

DNA Origami Nanopores

(2011) Nicholas A. W. Bell et al.   NANO LETTERS

Nanopore sensors for nucleic acid analysis

(2011) Bala Murali Venkatesan et al.   Nature Nanotechnology

Single-molecule transport across an individual biomimetic nuclear pore complex

(2011) Stefan W. Kowalczyk et al.   Nature Nanotechnology

Controlling protein translocation through nanopores with bio-inspired fluid walls

(2011) Erik C. Yusko et al.   Nature Nanotechnology

Evidence that small proteins translocate through silicon nitride pores in a folded conformation

(2010) Radu I Stefureac et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Single-Molecule Observation of Protein Adsorption onto an Inorganic Surface

(2010) David J. Niedzwiecki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Processive Replication of Single DNA Molecules in a Nanopore Catalyzed by phi29 DNA Polymerase

(2010) Kate R. Lieberman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrically Facilitated Translocations of Proteins through Silicon Nitride Nanopores: Conjoint and Competitive Action of Diffusion, Electrophoresis, and Electroosmosis

(2010) Matthias Firnkes et al.   NANO LETTERS

DNA Translocation through Graphene Nanopores

(2010) Christopher A. Merchant et al.   NANO LETTERS

Replication of individual DNA molecules under electronic control using a protein nanopore

(2010) Felix Olasagasti et al.   Nature Nanotechnology

Translocation of Single-Stranded DNA Through Single-Walled Carbon Nanotubes

(2010) H. Liu et al.   SCIENCE

Mapping the Position of DNA Polymerase-Bound DNA Templates in a Nanopore at 5 Å Resolution

(2009) Brett Gyarfas et al.   ACS Nano

Specific Nucleotide Binding and Rebinding to Individual DNA Polymerase Complexes Captured on a Nanopore

(2009) Nicholas Hurt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Molecule Protein Unfolding in Solid State Nanopores

(2009) David S. Talaga et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The structure of a cytolytic α-helical toxin pore reveals its assembly mechanism

(2009) Marcus Mueller et al.   NATURE

Translocation of double-stranded DNA through membrane-adapted phi29 motor protein nanopores

(2009) David Wendell et al.   Nature Nanotechnology

Origin of the electrophoretic force on DNA in solid-state nanopores

(2009) Stijn van Dorp et al.   Nature Physics

Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore

(2009) D. Stoddart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Label-Free Detection of Single Protein Molecules and Protein−Protein Interactions Using Synthetic Nanopores

(2008) Anpan Han et al.   ANALYTICAL CHEMISTRY

Electron beam nanosculpting of suspended graphene sheets

(2008) Michael D. Fischbein et al.   APPLIED PHYSICS LETTERS

Potential for Modulation of the Hydrophobic Effect Inside Chaperonins

(2008) Jeremy L. England et al.   BIOPHYSICAL JOURNAL

A Single-Molecule Nanopore Device Detects DNA Polymerase Activity with Single-Nucleotide Resolution

(2008) Scott L. Cockroft et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Role for Confined Water in Chaperonin Function

(2008) Jeremy L. England et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electro-osmotic screening of the DNA charge in a nanopore

(2008) Binquan Luan et al.   PHYSICAL REVIEW E

Single-molecule DNA detection with an engineered MspA protein nanopore

(2008) T. Z. Butler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperonin chamber accelerates protein folding through passive action of preventing aggregation

(2008) A. C. Apetri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Outer membrane protein G: Engineering a quiet pore for biosensing

(2008) M. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA