Review of Opioid Pharmacogenetics and Considerations for Pain Management

Life-Threatening Adverse Events Following Therapeutic Opioid Administration in Adults: Is Pharmacogenetic Analysis Useful?

(2016) Parvaz Madadi et al.   Pain Research & Management

Methadone Pharmacogenetics

(2015) Evan D. Kharasch et al.   ANESTHESIOLOGY

Pharmacogenomics in the clinic

(2015) Mary V. Relling et al.   NATURE

The pharmacogenetics of codeine pain relief in the postpartum period

(2015) M Baber et al.   PHARMACOGENOMICS JOURNAL

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update

(2014) K R Crews et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

How Much Oxycodone Is Needed for Adequate Analgesia After Breast Cancer Surgery: Effect of the OPRM1 118A>G Polymorphism

(2014) Kristiina Cajanus et al.   JOURNAL OF PAIN

Rescue morphine in mechanically ventilated newborns associated with combined OPRM1 and COMT genotype

(2014) Maja Matic et al.   PHARMACOGENOMICS

Opioid-induced respiratory depression: ABCB1 transporter pharmacogenetics

(2014) S Sadhasivam et al.   PHARMACOGENOMICS JOURNAL

The Effect of OPRM1 and COMT Genotypes on the Analgesic Response to Intravenous Fentanyl Labor Analgesia

(2013) Ruth Landau et al.   ANESTHESIA AND ANALGESIA

Gene Polymorphisms of OPRM1 A118G and ABCB1 C3435T May Influence Opioid Requirements in Chinese Patients with Cancer Pain

(2013) Xiao-Di Gong et al.   Asian Pacific Journal of Cancer Prevention

Hydrocodone in postoperative personalized pain management: Pro-drug or drug?

(2013) M. Elaine Stauble et al.   CLINICA CHIMICA ACTA

CYP2D6 Genotype Dependent Oxycodone Metabolism in Postoperative Patients

(2013) Ulrike M. Stamer et al.   PLoS One

Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance

(2013) Ulrich M. Zanger et al.   Frontiers in Genetics

Impact of CYP3A5 and ABCB1 Gene Polymorphisms on Fentanyl Pharmacokinetics and Clinical Responses in Cancer Patients Undergoing Conversion to a Transdermal System

(2012) Yoshiaki Takashina et al.   Drug Metabolism and Pharmacokinetics

Genetic Variation in the Catechol-O-Methyltransferase (COMT) Gene and Morphine Requirements in Cancer Patients with Pain

(2012) Trude T Rakvåg et al.   Molecular Pain

Suspected Opioid Overdose Case Resolved by CYP2D6 Genotyping

(2012) Kaitlyn D. Shaw et al.   THERAPEUTIC DRUG MONITORING

Human mu-opioid receptor gene A118G polymorphism predicts the efficacy of tramadol/acetaminophen combination tablets (ultracet) in oxaliplatin-induced painful neuropathy

(2011) Yu-Chang Liu et al.   CANCER

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Codeine Therapy in the Context of Cytochrome P450 2D6 (CYP2D6) Genotype

(2011) K R Crews et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A cross-sectional multicentre study

(2011) Trine Naalsund Andreassen et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

CYP3A5*3 Affects Plasma Disposition of Noroxycodone and Dose Escalation in Cancer Patients Receiving Oxycodone

(2011) Takafumi Naito et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Lack of Association ofOPRM1andABCB1Single-Nucleotide Polymorphisms to Oxycodone Response in Postoperative Pain

(2011) Stine T. Zwisler et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Influence from genetic variability on opioid use for cancer pain: A European genetic association study of 2294 cancer pain patients

(2011) P. Klepstad et al.   PAIN

CYP2D6 Polymorphisms and Codeine Analgesia in Postpartum Pain Management: A Pilot Study

(2011) Sondra vanderVaart et al.   THERAPEUTIC DRUG MONITORING

The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone

(2010) CF Samer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Fatal Hydrocodone Overdose in a Child: Pharmacogenetics and Drug Interactions

(2010) P. Madadi et al.   PEDIATRICS

Impact of theCYP2D6genotype on post-operative intravenous oxycodone analgesia

(2009) S. T. ZWISLER et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Mu-opioid receptor (A118G) single-nucleotide polymorphism affects alfentanil requirements for extracorporeal shock wave lithotripsy: a pharmacokinetic–pharmacodynamic study

(2009) Y. Ginosar et al.   BRITISH JOURNAL OF ANAESTHESIA

Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance

(2009) Shu-Feng Zhou   CLINICAL PHARMACOKINETICS

Effects of the CYP2D6 Gene Duplication on the Pharmacokinetics and Pharmacodynamics of Tramadol

(2009) Julia Kirchheiner et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Association between OPRM1 gene polymorphisms and fentanyl sensitivity in patients undergoing painful cosmetic surgery

(2009) Kenichi Fukuda et al.   PAIN

Respiratory Depression with Tramadol in a Patient with Renal Impairment and CYP2D6 Gene Duplication

(2008) Ulrike M. Stamer et al.   ANESTHESIA AND ANALGESIA

A118G Single Nucleotide Polymorphism of Human μ-Opioid Receptor Gene Influences Pain Perception and Patient-controlled Intravenous Morphine Consumption after Intrathecal Morphine for Postcesarean Analgesia

(2008) Alex T. Sia et al.   ANESTHESIOLOGY

Pharmacogenetics of Neonatal Opioid Toxicity Following Maternal Use of Codeine During Breastfeeding: A Case–Control Study

(2008) P Madadi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Analgesic requirements after major abdominal surgery are associated withOPRM1gene polymorphism genotype and haplotype

(2008) Masakazu Hayashida et al.   PHARMACOGENOMICS

UGT2B7 promoter variant −840G>A contributes to the variability in hepatic clearance of morphine in patients with sickle cell disease

(2007) Deepika S. Darbari et al.   AMERICAN JOURNAL OF HEMATOLOGY