Heat Shock Protein 27, a Novel Regulator of Transforming Growth Factor β Induced Resistance to Cisplatin in A549 Cell

A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers

(2016) K. N. Chi et al.   ANNALS OF ONCOLOGY

Confluence-dependent resistance to cisplatin in lung cancer cells is regulated by transforming growth factor-beta

(2016) Saki Yokokura et al.   EXPERIMENTAL LUNG RESEARCH

HSP27 regulates TGF-β mediated lung fibroblast differentiation through the Smad3 and ERK pathways

(2016) Gang Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Drug resistance originating from a TGF-β/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation

(2016) RYOTA KURIMOTO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

A Targetable Molecular Chaperone Hsp27 Confers Aggressiveness in Hepatocellular Carcinoma

(2016) Yurong Zhang et al.   Theranostics

Clinicopathological and prognostic significance of heat shock protein 27 (HSP27) expression in non-small cell lung cancer: a systematic review and meta-analysis

(2016) Shuangjiang Li et al.   SpringerPlus

Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp

(2015) Khalid O Alfarouk et al.   Cancer Cell International

Heat shock protein 27 promotes cell proliferation through activator protein-1 in lung cancer

(2015) SAI ZHANG et al.   Oncology Letters

TGFβSignaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis

(2015) Panagiotis Papageorgis   Journal of Oncology

The Mitochondrial Cardiolipin Remodeling Enzyme Lysocardiolipin Acyltransferase Is a Novel Target in Pulmonary Fibrosis

(2014) Long Shuang Huang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Immediate and transient phosphorylation of the heat shock protein 27 initiates chemoresistance in prostate cancer cells

(2014) MATTHIAS B. STOPE et al.   ONCOLOGY REPORTS

Lysophosphatidic Acid Receptor–2 Deficiency Confers Protection against Bleomycin-Induced Lung Injury and Fibrosis in Mice

(2013) Long Shuang Huang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation

(2013) Guillaume Wettstein et al.   FASEB JOURNAL

Activation of p38 mitogen-activated protein kinase in ovalbumin and ozone-induced mouse model of asthma

(2013) Li Liang et al.   RESPIROLOGY

Function of the p38MAPK-HSP27 Pathway in Rat Lung Injury Induced by Acute Ischemic Kidney Injury

(2013) Tao Ma et al.   Biomed Research International

Epidemiology of Lung Cancer

(2013) Carole Ridge et al.   SEMINARS IN INTERVENTIONAL RADIOLOGY

TGF-β-Smad3 signaling in emphysema and pulmonary fibrosis: an epigenetic aberration of normal development?

(2012) David Warburton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production

(2012) Carmela Guido et al.   CELL CYCLE

Down-regulation of heat-shock protein 27-induced resistance to photodynamic therapy in oral cancer cells

(2012) Jisun Kim et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Chemoresistance of lung cancer stemlike cells depends on activation of Hsp27

(2010) Han-Shui Hsu et al.   CANCER

Hsp27 Protects Adenocarcinoma Cells from UV-Induced Apoptosis by Akt and p21-Dependent Pathways of Survival

(2010) Ragu Kanagasabai et al.   MOLECULAR CANCER RESEARCH

Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E

(2010) C Andrieu et al.   ONCOGENE

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

(2009) Julian R. Molina et al.   MAYO CLINIC PROCEEDINGS

Non-Small Cell Lung Cancer in the Elderly: Defining Treatment Options

(2008) Nilesh Vora et al.   SEMINARS IN ONCOLOGY