The predictive value of ABCB1, ABCG2, CYP3A4/5 and CYP2D6 polymorphisms for risperidone and aripiprazole plasma concentrations and the occurrence of adverse drug reactions

Evidence-based recommendations for monitoring safety of second-generation antipsychotics in children and youth

(2017) Tamara Pringsheim et al.   Paediatrics & Child Health

The multidrug transporter ABCG2: still more questions than answers

(2016) A. J. Horsey et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Psychotropic drug use among 0–17 year olds during 2004–2014: a nationwide prescription database study

(2016) Ingeborg Hartz et al.   BMC Psychiatry

Dipeptidyl Peptidase (DPP)-4 Inhibitor-Induced Arthritis/Arthralgia: A Review of Clinical Cases

(2016) Annamaria Mascolo et al.   DRUG SAFETY

Second generation antipsychotics in ‘real-life’ paediatric patients. Adverse drug reactions and clinical outcomes of drug switch

(2016) Concetta Rafaniello et al.   Expert Opinion On Drug Safety

Campania preventability assessment committee: a focus on the preventability of the contrast media adverse drug reactions

(2016) Maurizio Sessa et al.   Expert Opinion On Drug Safety

No substantial gender differences in suspected adverse reactions to ACE inhibitors and ARBs: results from spontaneous reporting system in Campania Region

(2016) Liberata Sportiello et al.   Expert Opinion On Drug Safety

The importance of Pharmacovigilance for the drug safety: Focus on cardiovascular profile of incretin-based therapy

(2016) Liberata Sportiello et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Persistence in Therapy With Risperidone and Aripiprazole in Pediatric Outpatients

(2016) Marco Pozzi et al.   JOURNAL OF CLINICAL PSYCHIATRY

ABC transporters P-gp and Bcrp do not limit the brain uptake of the novel antipsychotic and anticonvulsant drug cannabidiol in mice

(2016) Natalia Brzozowska et al.   PeerJ

Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

(2015) Miriam G. Mooij et al.   CLINICAL PHARMACOKINETICS

Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group

(2015) KLR Brouwer et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Psychotropic medicine prescriptions in Italian youths: a multiregional study

(2015) Daniele Piovani et al.   EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

Antipsychotic prescribing in youths: a French community-based study from 2006 to 2013

(2015) Hélène Verdoux et al.   EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

Therapeutic drug monitoring of second-generation antipsychotics in pediatric patients: an observational study in real-life settings

(2015) Marco Pozzi et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

The Influence of the CYP3A4*22 Polymorphism and CYP2D6 Polymorphisms on Serum Concentrations of Aripiprazole, Haloperidol, Pimozide, and Risperidone in Psychiatric Patients

(2015) Karen van der Weide et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

The ontogeny of P-glycoprotein in the developing human blood–brain barrier: implication for opioid toxicity in neonates

(2015) Jessica Lam et al.   PEDIATRIC RESEARCH

Trends in psychopharmacologic treatment of tic disorders in children and adolescents in Germany

(2014) Christian J. Bachmann et al.   EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

Recent international trends in psychotropic medication prescriptions for children and adolescents

(2014) Hans-Christoph Steinhausen   EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance

(2014) Oliver Bruhn et al.   Expert Opinion on Drug Metabolism & Toxicology

Clinical applications of CYP genotyping in psychiatry

(2014) Edoardo Spina et al.   JOURNAL OF NEURAL TRANSMISSION

Effects of Genetic Polymorphisms of CYP2D6, CYP3A5, and ABCB1 on the Steady-State Plasma Concentrations of Aripiprazole and Its Active Metabolite, Dehydroaripiprazole, in Japanese Patients With Schizophrenia

(2014) Takeshi Suzuki et al.   THERAPEUTIC DRUG MONITORING

Impact of genetic deficiencies of P-glycoprotein and breast cancer resistance protein on pharmacokinetics of aripiprazole and dehydroaripiprazole

(2014) Yasuhisa Nagasaka et al.   XENOBIOTICA

Transporters in Drug Development and Clinical Pharmacology

(2013) K M Giacomini et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Use of Antipsychotic Medications in Pediatric Populations: What do the Data Say?

(2013) Robert B. Penfold et al.   Current Psychiatry Reports

Safety and Pharmacokinetics of Atypical Antipsychotics in Children and Adolescents

(2013) Silvio Caccia   PEDIATRIC DRUGS

Phenotyping and Genotyping of Drug Metabolism to Guide Pharmacotherapy in Psychiatry

(2013) Christoph Hiemke et al.   Current Drug Delivery

National Trends in the Office-Based Treatment of Children, Adolescents, and Adults With Antipsychotics

(2012) Mark Olfson et al.   ARCHIVES OF GENERAL PSYCHIATRY

Effects of aripiprazole and its active metabolite dehydroaripiprazole on the activities of drug efflux transporters expressed both in the intestine and at the blood-brain barrier

(2012) Yasuhisa Nagasaka et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Antipsychotics in pediatric and adolescent patients: A review of comparative safety data

(2012) Leila Ben Amor   JOURNAL OF AFFECTIVE DISORDERS

Antipsychotic Medication Prescribing Trends in Children and Adolescents

(2012) Joyce Nolan Harrison et al.   Journal of Pediatric Health Care

Influence ofABCB1genetic polymorphisms on the pharmacokinetics of risperidone in healthy subjects withCYP2D6*10/*10

(2011) Hee-Doo Yoo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Differential expression of ABC transporters (MDR1, MRP1, BCRP) in developing human embryos

(2011) A. Konieczna et al.   JOURNAL OF MOLECULAR HISTOLOGY

Effect of CYP2D6, CYP3A5, and MDR1 Genetic Polymorphisms on the Pharmacokinetics of Risperidone and Its Active Moiety

(2010) Qian Xiang et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Understanding transport through pharmacological barriers — are we there yet?

(2010) Balázs Sarkadi et al.   NATURE REVIEWS DRUG DISCOVERY

Transporters in drug development: advancing on the Critical Path

(2010) Shiew-Mei Huang et al.   NATURE REVIEWS DRUG DISCOVERY

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Pharmacokinetics of acute and sub-chronic aripiprazole in P-glycoprotein deficient mice

(2010) Katrin M. Kirschbaum et al.   NEUROPHARMACOLOGY

Regulation of P-glycoprotein and other ABC drug transporters at the blood–brain barrier

(2010) David S. Miller   TRENDS IN PHARMACOLOGICAL SCIENCES

Measurement and Estimation of GFR in Children and Adolescents

(2009) G. J. Schwartz et al.   Clinical Journal of the American Society of Nephrology

Body Mass Index Is Associated with Increased Creatinine Clearance by a Mechanism Independent of Body Fat Distribution

(2009) Fernando Gerchman et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Sexual Dysfunction in Patients Treated With Atypical Antipsychotics

(2009) Jonathan M. Meyer   JOURNAL OF CLINICAL PSYCHIATRY

On the relationship between glomerular filtration rate and serum creatinine in children

(2009) Hans Pottel et al.   PEDIATRIC NEPHROLOGY

Aripiprazole brain concentration is altered in P-glycoprotein deficient mice

(2009) Jun-Sheng Wang et al.   SCHIZOPHRENIA RESEARCH

Antipsychotic Drugs Inhibit the Function of Breast Cancer Resistance Protein

(2008) Jun-Sheng Wang et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier

(2008) Sandrine Dauchy et al.   JOURNAL OF NEUROCHEMISTRY

Major SNP (Q141K) Variant of Human ABC Transporter ABCG2 Undergoes Lysosomal and Proteasomal Degradations

(2008) Tomoka Furukawa et al.   PHARMACEUTICAL RESEARCH

The ontogeny of drug metabolism enzymes and implications for adverse drug events

(2008) Ronald N. Hines   PHARMACOLOGY & THERAPEUTICS

ABCB1 Polymorphisms Influence Steady-State Plasma Levels of 9-Hydroxyrisperidone and Risperidone Active Moiety

(2008) Arzu Gunes et al.   THERAPEUTIC DRUG MONITORING