Epigenomics alternations and dynamic transcriptional changes in responses to 5-fluorouracil stimulation reveal mechanisms of acquired drug resistance of colorectal cancer cells

Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

(2015) Stine Ninel Hansen et al.   TUMOR BIOLOGY

MiR-215, an activator of the CTNNBIP1/β-catenin pathway, is a marker of poor prognosis in human glioma

(2015) Yong-Qing Tong et al.   Oncotarget

Identification of reproducible drug-resistance-related dysregulated genes in small-scale cancer cell line experiments

(2015) Lu Ao et al.   Scientific Reports

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(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Genomic analysis of drug resistant gastric cancer cell lines by combining mRNA and microRNA expression profiling

(2014) Zhangqian Chen et al.   CANCER LETTERS

GPx2 Suppression of H2O2 Stress Links the Formation of Differentiated Tumor Mass to Metastatic Capacity in Colorectal Cancer

(2014) B. L. Emmink et al.   CANCER RESEARCH

Drug Resistance in Cancer: An Overview

(2014) Genevieve Housman et al.   Cancers

In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies

(2014) Martina McDermott et al.   Frontiers in Oncology

Enhancement of 5-fluorouracil-induced cytotoxicity by leucovorin in 5-fluorouracil-resistant gastric cancer cells with upregulated expression of thymidylate synthase

(2013) Ayako Nakamura et al.   Gastric Cancer

Biopsies: next-generation biospecimens for tailoring therapy

(2013) Mark Basik et al.   Nature Reviews Clinical Oncology

DrugBank 4.0: shedding new light on drug metabolism

(2013) Vivian Law et al.   NUCLEIC ACIDS RESEARCH

An Integrated Approach to Uncover Driver Genes in Breast Cancer Methylation Genomes

(2013) Xiaopei Shen et al.   PLoS One

Silencing of DLGAP5 by siRNA Significantly Inhibits the Proliferation and Invasion of Hepatocellular Carcinoma Cells

(2013) Weijia Liao et al.   PLoS One

Mechanistic evaluation of the signaling events regulating curcumin-mediated chemosensitization of breast cancer cells to 5-fluorouracil

(2013) B S Vinod et al.   Cell Death & Disease

MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL

(2012) Alexander Baraniskin et al.   CARCINOGENESIS

Applications of Connectivity Map in drug discovery and development

(2012) Xiaoyan A. Qu et al.   DRUG DISCOVERY TODAY

Studying and modelling dynamic biological processes using time-series gene expression data

(2012) Ziv Bar-Joseph et al.   NATURE REVIEWS GENETICS

Omics and Drug Response

(2011) Urs A. Meyer et al.   Annual Review of Pharmacology and Toxicology

Adjuvant therapy in colon cancer

(2011) Janet S Graham et al.   Expert Review of Anticancer Therapy

Proposals for uniform collection of biospecimens from neoadjuvant breast cancer clinical trials: timing and specimen types

(2011) Sherene Loi et al.   LANCET ONCOLOGY

KEGG for integration and interpretation of large-scale molecular data sets

(2011) M. Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

(2011) J.-P. Gillet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5-Fluorouracil Adjuvant Chemotherapy Does Not Increase Survival in Patients With CpG Island Methylator Phenotype Colorectal Cancer

(2010) Rodrigo Jover et al.   GASTROENTEROLOGY

Pharmacogenomics and bioinformatics: PharmGKB

(2010) Caroline F Thorn et al.   PHARMACOGENOMICS

Relationship between expression of 5-fluorouracil metabolic enzymes and 5-fluorouracil sensitivity in esophageal carcinoma cell lines

(2007) T. Ando et al.   DISEASES OF THE ESOPHAGUS