Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

Do predictive signatures really predict response to cancer chemotherapy? 

(2011) Piet Borst et al.   CELL CYCLE

Advances in the Molecular Detection of ABC Transporters Involved in Multidrug Resistance in Cancer

(2011) Jean-Pierre Gillet et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Systematic Evaluation of Three microRNA Profiling Platforms: Microarray, Beads Array, and Quantitative Real-Time PCR Array

(2011) Bin Wang et al.   PLoS One

Molecular characterization of ovarian cancer by gene-expression profiling

(2010) C. Gómez-Raposo et al.   GYNECOLOGIC ONCOLOGY

Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics

(2010) Anna Maria Calcagno et al.   JNCI-Journal of the National Cancer Institute

How accurate are cancer cell lines?

(2010) Brendan Borrell   NATURE

A global map of human gene expression

(2010) Margus Lukk et al.   NATURE BIOTECHNOLOGY

Transcriptional Regulation by P53

(2010) R. Beckerman et al.   Cold Spring Harbor Perspectives in Biology

ABC transporter A3 facilitates lysosomal sequestration of imatinib and modulates susceptibility of chronic myeloid leukemia cell lines to this drug

(2009) B. Chapuy et al.   HAEMATOLOGICA

Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database

(2009) J. N. Orina et al.   MOLECULAR CANCER THERAPEUTICS

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Lost in translation: Problems and pitfalls in translating laboratory observations to clinical utility

(2008) Richard Simon   EUROPEAN JOURNAL OF CANCER

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute

Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration

(2008) B Chapuy et al.   LEUKEMIA

A complex barcode underlies the heterogeneous response of p53 to stress

(2008) Fiona Murray-Zmijewski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gene-expression profiling in epithelial ovarian cancer

(2008) Panagiotis A Konstantinopoulos et al.   Nature clinical practice. Oncology