Quantitative profiling of the UGT transcriptome in human drug-metabolizing tissues

Cross-Talk between Alternatively Spliced UGT1A Isoforms and Colon Cancer Cell Metabolism

(2017) Yannick Audet-Delage et al.   MOLECULAR PHARMACOLOGY

HGVS Recommendations for the Description of Sequence Variants: 2016 Update

(2016) Johan T. den Dunnen et al.   HUMAN MUTATION

Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines

(2016) A Chhibber et al.   PHARMACOGENOMICS JOURNAL

Divergent Expression and Metabolic Functions of Human Glucuronosyltransferases through Alternative Splicing

(2016) Michèle Rouleau et al.   Cell Reports

Unravelling the transcriptomic landscape of the major phase II UDP-glucuronosyltransferase drug metabolizing pathway using targeted RNA sequencing

(2015) A Tourancheau et al.   PHARMACOGENOMICS JOURNAL

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Pharmacogenomics of Human Uridine Diphospho-Glucuronosyltransferases and Clinical Implications

(2014) C Guillemette et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Finding the active genes in deep RNA-seq gene expression studies

(2013) Traver Hart et al.   BMC GENOMICS

Expression of UGT2B7 is driven by two mutually exclusive promoters and alternative splicing in human tissues

(2013) Vincent Ménard et al.   Pharmacogenetics and Genomics

Relevance of UDP-glucuronosyltransferase polymorphisms for drug dosing: A quantitative systematic review

(2013) J.C. Stingl et al.   PHARMACOLOGY & THERAPEUTICS

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Identification of Residues That Confer Sugar Selectivity to UDP-Glycosyltransferase 3A (UGT3A) Enzymes

(2012) Robyn Meech et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Transcriptional diversity at the UGT2B7 locus is dictated by extensive pre-mRNA splicing mechanisms that give rise to multiple mRNA splice variants

(2011) Vincent Ménard et al.   Pharmacogenetics and Genomics

Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues

(2011) Michael H. Court et al.   XENOBIOTICA

Immunohistochemical expression of conjugating UGT1A-derived isoforms in normal and tumoral drug-metabolizing tissues in humans

(2010) Judith Bellemare et al.   JOURNAL OF PATHOLOGY

The Novel UDP Glycosyltransferase 3A2: Cloning, Catalytic Properties, and Tissue Distribution

(2010) P. I. MacKenzie et al.   MOLECULAR PHARMACOLOGY

Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGT2B4 modulates glucuronidation

(2010) Eric Lévesque et al.   Pharmacogenetics and Genomics

Modulation of the Human Glucuronosyltransferase UGT1A Pathway by Splice Isoform Polypeptides Is Mediated through Protein-Protein Interactions

(2009) Judith Bellemare et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction

(2008) S. Ohno et al.   DRUG METABOLISM AND DISPOSITION

Identification of UDP Glycosyltransferase 3A1 as a UDPN-Acetylglucosaminyltransferase

(2008) Peter I. Mackenzie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY