New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Mechanisms of the placebo effect in pain and psychiatric disorders

(2016) R D Holmes et al.   PHARMACOGENOMICS JOURNAL

Genetics of long-term treatment outcome in bipolar disorder

(2016) Chiara Fabbri et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Efficacy and safety of quetiapine extended release monotherapy in bipolar depression: a multi-center, randomized, double-blind, placebo-controlled trial

(2016) Huafang Li et al.   PSYCHOPHARMACOLOGY

Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response

(2016) Q S Li et al.   Translational Psychiatry

Changes in cortical N-methyl-d-aspartate receptors and post-synaptic density protein 95 in schizophrenia, mood disorders and suicide

(2015) Brian Dean et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

The tetrapartite synapse: Extracellular matrix remodeling contributes to corticoaccumbens plasticity underlying drug addiction

(2015) Alexander C.W. Smith et al.   BRAIN RESEARCH

Protein synthesis and consolidation of memory-related synaptic changes

(2015) Gary Lynch et al.   BRAIN RESEARCH

Homozygous loss-of-function variants in European cosmopolitan and isolate populations

(2015) Vera B. Kaiser et al.   HUMAN MOLECULAR GENETICS

A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Vortioxetine 10 mg and 20 mg in Adults With Major Depressive Disorder

(2015) Paula L. Jacobsen et al.   JOURNAL OF CLINICAL PSYCHIATRY

CHL1, ITGB3 and SLC6A4 gene expression and antidepressant drug response: results from the Munich Antidepressant Response Signature (MARS) study

(2015) Kristina Probst-Schendzielorz et al.   PHARMACOGENOMICS

Pharmacogenomic variants have larger effect sizes than genetic variants associated with other dichotomous complex traits

(2015) J C Maranville et al.   PHARMACOGENOMICS JOURNAL

Neuronal cell adhesion genes and antidepressant response in three independent samples

(2015) C Fabbri et al.   PHARMACOGENOMICS JOURNAL

Two Phase III randomised double-blind studies of fixed-dose TC-5214 (dexmecamylamine) adjunct to ongoing antidepressant therapy in patients with major depressive disorder and an inadequate response to prior antidepressant therapy

(2015) Hans-Jürgen Möller et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Full UPF3B function is critical for neuronal differentiation of neural stem cells

(2015) Tahani Alrahbeni et al.   Molecular Brain

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response

(2015) J M Biernacka et al.   Translational Psychiatry

Pamheterozygous mice reveal essential role for Cu in amygdalar behavioral and synaptic function

(2014) Eric D. Gaier et al.   Annals of the New York Academy of Sciences

Rare variant genotype imputation with thousands of study-specific whole-genome sequences: implications for cost-effective study designs

(2014) Giorgio Pistis et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

DISC1-TSNAX and DAOA genes in major depression and citalopram efficacy

(2014) Bárbara Arias et al.   JOURNAL OF AFFECTIVE DISORDERS

Treatment Outcomes of Depression

(2014) David A. Mrazek et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Large-scale genomics unveils the genetic architecture of psychiatric disorders

(2014) Jacob Gratten et al.   NATURE NEUROSCIENCE

What Did STAR*D Teach Us? Results From a Large-Scale, Practical, Clinical Trial for Patients With Depression

(2014) Bradley N. Gaynes et al.   PSYCHIATRIC SERVICES

Pharmacogenetics of antidepressant drugs: An update after almost 20 years of research

(2013) Chiara Fabbri et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Common Genetic Variation and Antidepressant Efficacy in Major Depressive Disorder: A Meta-Analysis of Three Genome-Wide Pharmacogenetic Studies

(2013) et al.   AMERICAN JOURNAL OF PSYCHIATRY

Pharmacogenomic Testing and Personalized Treatment of Depression

(2013) R. H. Perlis   CLINICAL CHEMISTRY

Further confirmation of the association between anxiety andCTNND2: replication in humans

(2013) M. G. Nivard et al.   GENES BRAIN AND BEHAVIOR

The State of US Health, 1990-2010

(2013) Christopher J. L. Murray   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

High-Mobility Group Box-1 Protein and  -Amyloid Oligomers Promote Neuronal Differentiation of Adult Hippocampal Neural Progenitors via Receptor for Advanced Glycation End Products/Nuclear Factor- B Axis: Relevance for Alzheimer's Disease

(2013) V. Meneghini et al.   JOURNAL OF NEUROSCIENCE

A genome-wide association study of a sustained pattern of antidepressant response

(2013) Aimee M. Hunter et al.   JOURNAL OF PSYCHIATRIC RESEARCH

708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits

(2013) P A Thomson et al.   MOLECULAR PSYCHIATRY

Contribution of Common Genetic Variants to Antidepressant Response

(2012) Katherine E. Tansey et al.   BIOLOGICAL PSYCHIATRY

Biomarkers predicting treatment outcome in depression: what is clinically significant?

(2012) Rudolf Uher et al.   PHARMACOGENOMICS

Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: genome-wide associations and functional genomics

(2012) Y Ji et al.   PHARMACOGENOMICS JOURNAL

Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability

(2012) Hidenori Tani et al.   RNA Biology

Genetic Predictors of Response to Serotonergic and Noradrenergic Antidepressants in Major Depressive Disorder: A Genome-Wide Analysis of Individual-Level Data and a Meta-Analysis

(2012) Katherine E. Tansey et al.   PLOS MEDICINE

Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode

(2012) R Belzeaux et al.   Translational Psychiatry

GWAPower: a statistical power calculation software for genome-wide association studies with quantitative traits

(2011) Sheng Feng et al.   BMC GENETICS

Autoregulation of the nonsense-mediated mRNA decay pathway in human cells

(2011) H. Yepiskoposyan et al.   RNA

Development of a Neural Teratogenicity Test Based on Human Embryonic Stem Cells: Response to Retinoic Acid Exposure

(2011) Silvia Colleoni et al.   TOXICOLOGICAL SCIENCES

Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP Project

(2010) Rudolf Uher et al.   AMERICAN JOURNAL OF PSYCHIATRY

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Antidepressant Drug Effects and Depression Severity

(2010) Jay C. Fournier et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Processing of the Synaptic Cell Adhesion Molecule Neurexin-3β by Alzheimer Disease α- and γ-Secretases

(2010) Nathalie Bot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Haploinsufficiency in Peptidylglycine  -Amidating Monooxygenase Leads to Altered Synaptic Transmission in the Amygdala and Impaired Emotional Responses

(2010) E. D. Gaier et al.   JOURNAL OF NEUROSCIENCE

Convergence of linkage, association and GWAS findings for a candidate region for bipolar disorder and schizophrenia on chromosome 4p

(2010) A Christoforou et al.   MOLECULAR PSYCHIATRY

Data quality control in genetic case-control association studies

(2010) Carl A Anderson et al.   Nature Protocols

The glucocorticoid receptor: Pivot of depression and of antidepressant treatment?

(2010) Christoph Anacker et al.   PSYCHONEUROENDOCRINOLOGY

Family-based association ofYWHAHin psychotic bipolar disorder

(2009) Deepak Grover et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

A Genomewide Association Study Points to Multiple Loci That Predict Antidepressant Drug Treatment Outcome in Depression

(2009) Marcus Ising et al.   ARCHIVES OF GENERAL PSYCHIATRY

A Genomewide Association Study of Citalopram Response in Major Depressive Disorder

(2009) Holly A. Garriock et al.   BIOLOGICAL PSYCHIATRY

Association of DISC1 and TSNAX genes and affective disorders in the depression case–control (DeCC) and bipolar affective case–control (BACCS) studies

(2009) A Schosser et al.   MOLECULAR PSYCHIATRY

Novel consortium to address shortfall in innovative medicines for psychiatric disorders

(2009) Bethan Hughes   NATURE REVIEWS DRUG DISCOVERY

Translin-Associated Factor X Gene (TSNAX) may be Associated with Female major Depressive Disorder in the Japanese Population

(2009) Akiko Okuda et al.   NEUROMOLECULAR MEDICINE

Long-term suicide risk of depression in the Lundby cohort 1947–1997 – severity and gender

(2008) L. Brådvik et al.   ACTA PSYCHIATRICA SCANDINAVICA

Estimation of significance thresholds for genomewide association scans

(2008) Frank Dudbridge et al.   GENETIC EPIDEMIOLOGY

GENetic and clinical Predictors Of treatment response in Depression: the GenPod randomised trial protocol

(2008) Laura Thomas et al.   Trials