The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, Pulmonary Specific Disposition

Title
The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, Pulmonary Specific Disposition
Authors
Keywords
efflux, isolated perfused lung, lung, MDR, <em class=EmphasisTypeItalic >Mdr</em>, physico-chemical, pulmonary absorption, P-glycoprotein (P-gp), QSAR, transporter
Journal
PHARMACEUTICAL RESEARCH
Volume 34, Issue 12, Pages 2498-2516
Publisher
Springer Nature
Online
2017-07-12
DOI
10.1007/s11095-017-2220-5

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