Postnatal human enteric neuronal progenitors can migrate, differentiate, and proliferate in embryonic and postnatal aganglionic gut environments

Delivery of enteric neural progenitors with 5-HT4 agonist-loaded nanoparticles and thermosensitive hydrogel enhances cell proliferation and differentiation following transplantation in vivo

(2016) Ryo Hotta et al.   BIOMATERIALS

Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease

(2016) Faranak Fattahi et al.   NATURE

In Vivo Transplantation of Enteric Neural Crest Cells into Mouse Gut; Engraftment, Functional Integration and Long-Term Safety

(2016) Julie E. Cooper et al.   PLoS One

Sonic hedgehog controls enteric nervous system development by patterning the extracellular matrix

(2015) Nandor Nagy et al.   DEVELOPMENT

Isogenic enteric neural progenitor cells can replace missing neurons and glia in mice with Hirschsprung disease

(2015) R. Hotta et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Isolation of Enteric Nervous System Progenitor Cells from the Aganglionic Gut of Patients with Hirschsprung’s Disease

(2015) David J. Wilkinson et al.   PLoS One

Isolation of high-purity myenteric plexus from adult human and mouse gastrointestinal tract

(2015) David Grundmann et al.   Scientific Reports

Comparative proteomic profiles of the normal and aganglionic hindgut in human Hirschsprung disease

(2014) Shu-Cheng Zhang et al.   PEDIATRIC RESEARCH

In Vivo Transplantation of Neurosphere-Like Bodies Derived from the Human Postnatal and Adult Enteric Nervous System: A Pilot Study

(2014) Susan Hetz et al.   PLoS One

Neural stem cell therapies for enteric nervous system disorders

(2013) Alan J. Burns et al.   Nature Reviews Gastroenterology & Hepatology

The Human Gastrointestinal Tract, a Potential Autologous Neural Stem Cell Source

(2013) Cornelia Irene Hagl et al.   PLoS One

Divergent fate and origin of neurosphere-like bodies from different layers of the gut

(2012) Laren Becker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Building a brain in the gut: development of the enteric nervous system

(2012) AM Goldstein et al.   CLINICAL GENETICS

The enteric nervous system and neurogastroenterology

(2012) John B. Furness   Nature Reviews Gastroenterology & Hepatology

Future therapies for Hirschsprung's disease

(2012) David J. Wilkinson et al.   Seminars in Pediatric Surgery

Long-term outcomes and the quality of life of Hirschsprung disease in adolescents who have reached 18 years or older—a 47-year single-institute experience

(2010) Satoshi Ieiri et al.   JOURNAL OF PEDIATRIC SURGERY

Expansion and Differentiation of Neural Progenitors Derived From the Human Adult Enteric Nervous System

(2009) Marco Metzger et al.   GASTROENTEROLOGY

Enteric Nervous System Stem Cells Derived From Human Gut Mucosa for the Treatment of Aganglionic Gut Disorders

(2009) Marco Metzger et al.   GASTROENTEROLOGY

Properties of secondary and tertiary human enteric nervous system neurospheres

(2009) Richard M. Lindley et al.   JOURNAL OF PEDIATRIC SURGERY

Potential of cell therapy to treat pediatric motility disorders

(2009) Ryo Hotta et al.   Seminars in Pediatric Surgery

Human and Mouse Enteric Nervous System Neurosphere Transplants Regulate the Function of Aganglionic Embryonic Distal Colon

(2008) Richard M. Lindley et al.   GASTROENTEROLOGY

Diminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice

(2008) Toshihiro Uesaka et al.   JOURNAL OF CLINICAL INVESTIGATION