The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain
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Title
The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain
Authors
Keywords
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Journal
Oxidative Medicine and Cellular Longevity
Volume 2017, Issue -, Pages 1-14
Publisher
Hindawi Limited
Online
2017-01-11
DOI
10.1155/2017/4680732
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Note: Only part of the references are listed.- A dual inhibition: microRNA-552 suppresses both transcription and translation of cytochrome P450 2E1
- (2016) Lingling Miao et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain Function
- (2016) Carla Garza-Lombó et al. Frontiers in Cellular Neuroscience
- Severe psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1
- (2016) R Kumsta et al. Translational Psychiatry
- Autophagy Constitutes a Protective Mechanism against Ethanol Toxicity in Mouse Astrocytes and Neurons
- (2016) Antoni Pla et al. PLoS One
- Expression of CYP2E1 and CYP2U1 Proteins in Amygdala and Prefrontal Cortex: Influence of Alcoholism and Smoking
- (2015) Francesca Toselli et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Cytochrome P450 expression in mouse brain: specific isoenzymes involved in Phase I metabolizing system of porphyrinogenic agents in both microsomes and mitochondria
- (2015) Jimena Lavandera et al. Biochemistry and Cell Biology
- The acute and chronic toxic effect of cypermethrin, propetamphos, and their combinations in rats
- (2015) Gökhan Eraslan et al. ENVIRONMENTAL TOXICOLOGY
- Insulin receptor A and Sirtuin 1 synergistically improve learning and spatial memory following chronic salidroside treatment during hypoxia
- (2015) Kalpana Barhwal et al. JOURNAL OF NEUROCHEMISTRY
- Gene expression profiling of cytochromes P450, ABC transporters and their principal transcription factors in the amygdala and prefrontal cortex of alcoholics, smokers and drug-free controls by qRT-PCR
- (2015) Francesca Toselli et al. XENOBIOTICA
- Hyperlipidemia exacerbates cerebral injury through oxidative stress, inflammation and neuronal apoptosis in MCAO/reperfusion rats
- (2015) Xiao-Lu Cao et al. EXPERIMENTAL BRAIN RESEARCH
- Isoniazid-induced polyneuropathy in a tuberculosis patient - implication for individual risk stratification with genotyping?
- (2015) Mark Stettner et al. Brain and Behavior
- Aspartame Administration and Insulin Treatment Altered Brain Levels of CYP2E1 and CYP3A2 in Streptozotocin-Induced Diabetic Rats
- (2014) Rosario Nosti-Palacios et al. INTERNATIONAL JOURNAL OF TOXICOLOGY
- Haplotype-based study of the association of alcohol and acetaldehyde-metabolising genes with alcohol dependence (with or without comorbid anxiety symptoms) in a Cape Mixed Ancestry population
- (2014) Andrew Crawford et al. METABOLIC BRAIN DISEASE
- Potent Effects of Flavonoid-Rich Extract from Rosa laevigata Michx Fruit against Hydrogen Peroxide-Induced Damage in PC12 Cells via Attenuation of Oxidative Stress, Inflammation and Apoptosis
- (2014) Min Liu et al. MOLECULES
- Induction of brain cytochrome P450 2E1 boosts the locomotor-stimulating effects of ethanol in mice
- (2014) Juan Carlos Ledesma et al. NEUROPHARMACOLOGY
- Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression
- (2014) B. Boussadia et al. NEUROSCIENCE
- Thioredoxin System Regulation in the Central Nervous System: Experimental Models and Clinical Evidence
- (2014) Daniela Silva-Adaya et al. Oxidative Medicine and Cellular Longevity
- CYP2E1 induction leads to oxidative stress and cytotoxicity in glutathione-depleted cerebellar granule neurons
- (2014) Ana Carolina Valencia-Olvera et al. TOXICOLOGY IN VITRO
- Drug and xenobiotic biotransformation in the blood–brain barrier: a neglected issue
- (2014) José A. G. Agúndez et al. Frontiers in Cellular Neuroscience
- Temporal changes of cytochrome P450 (Cyp) and eicosanoid-related gene expression in the rat brain after traumatic brain injury
- (2013) Matthew Birnie et al. BMC GENOMICS
- Neurotoxicity and gene-expressed profile in brain-injured mice caused by exposure to titanium dioxide nanoparticles
- (2013) Yuguan Ze et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Expression of autophagy and UPR genes in the developing brain during ethanol-sensitive and resistant periods
- (2013) Alexander Alimov et al. METABOLIC BRAIN DISEASE
- Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys
- (2013) Charmaine S. Ferguson et al. NEUROPHARMACOLOGY
- Locally-generated acetaldehyde is involved in ethanol-mediated LTP inhibition in the hippocampus
- (2013) Kazuhiro Tokuda et al. NEUROSCIENCE LETTERS
- Regulation of cytochrome P450 2e1 expression by ethanol: role of oxidative stress-mediated pkc/jnk/sp1 pathway
- (2013) M Jin et al. Cell Death & Disease
- Acetaldehyde and parkinsonism: role of CYP450 2E1
- (2013) Francesca Vaglini et al. Frontiers in Behavioral Neuroscience
- Autophagy is a protective response to ethanol neurotoxicity
- (2012) Gang Chen et al. Autophagy
- Alcohol and risk of Parkinson's disease in a large, prospective cohort of men and women
- (2012) Natalia Palacios et al. MOVEMENT DISORDERS
- The role of amino acid transporters in GSH synthesis in the blood–brain barrier and central nervous system
- (2012) Cesar Valdovinos-Flores et al. NEUROCHEMISTRY INTERNATIONAL
- Genome-scale methylation analysis of Parkinson's disease patients' brains reveals DNA hypomethylation and increased mRNA expression of cytochrome P450 2E1
- (2012) Oliver Kaut et al. NEUROGENETICS
- Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem
- (2012) Yanjun Zhong et al. TOXICOLOGY
- Oxidative Stress and Antioxidant Defense
- (2012) Esra Birben et al. World Allergy Organization Journal
- Independent and Combined Effects of Ethanol Self-Administration and Nicotine Treatment on Hepatic CYP2E1 in African Green Monkeys
- (2011) C. S. Ferguson et al. DRUG METABOLISM AND DISPOSITION
- Epidemiology and etiology of Parkinson’s disease: a review of the evidence
- (2011) Karin Wirdefeldt et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Mechanisms of mitochondrial targeting of cytochrome P450 2E1: physiopathological role in liver injury and obesity
- (2011) Laetitia Knockaert et al. FEBS Journal
- Effect of mosquito mats (pyrethroid-based) vapor inhalation on rat brain cytochrome P450s
- (2011) Araceli Vences-Mejía et al. TOXICOLOGY MECHANISMS AND METHODS
- Cytochrome P450 enzymes in the brain: emerging evidence of biological significance
- (2011) Charmaine S. Ferguson et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Ethanol and acetaldehyde disturb TNF-alpha and IL-6 production in cultured astrocytes
- (2010) Lucija Sarc et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Determination of brain cytochrome P450 2E1 activity in rat with the probe of chlorzoxazone by liquid chromatography–mass spectrometry
- (2010) Jian-Yuan Wu et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen
- (2010) Laetitia Knockaert et al. TOXICOLOGY IN VITRO
- Aquaporin-4 knockout enhances astrocyte toxicity induced by 1-methyl-4-phenylpyridinium ion and lipopolysaccharide via increasing the expression of cytochrome P4502E1
- (2010) Chunshu Hao et al. TOXICOLOGY LETTERS
- Human CYP2E1 is regulated by miR-378
- (2009) Takuya Mohri et al. BIOCHEMICAL PHARMACOLOGY
- Polymorphic Drug Metabolism in Anaesthesia
- (2009) Juan Restrepo et al. CURRENT DRUG METABOLISM
- Xenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral Function
- (2009) F. Dutheil et al. DRUG METABOLISM AND DISPOSITION
- Polymorphism of human cytochrome P450 enzymes and its clinical impact
- (2009) Shu-Feng Zhou et al. DRUG METABOLISM REVIEWS
- Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake
- (2009) Jiang Yue et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Variability in ethanol biodisposition in whites is modulated by polymorphisms in theADH1BandADH1Cgenes
- (2009) Carmen Martínez et al. HEPATOLOGY
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- MPTP-induced model of Parkinson's disease in cytochrome P450 2E1knockout mice
- (2009) C. Viaggi et al. NEUROPHARMACOLOGY
- Ethanol intake and ethanol-induced locomotion and locomotor sensitization in Cyp2e1 knockout mice
- (2009) Mercè Correa et al. Pharmacogenetics and Genomics
- ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier
- (2008) Sandrine Dauchy et al. JOURNAL OF NEUROCHEMISTRY
- Polymorphism in environment responsive genes and association with Parkinson disease
- (2008) Madhu Singh et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- The role of antioxidants and antioxidant-related enzymes in protective responses to environmentally induced oxidative stress
- (2008) Jorge Limón-Pacheco et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Role of CYP2E1 in the mouse model of MPTP toxicity
- (2008) Carla Pardini et al. PARKINSONISM & RELATED DISORDERS
- CYP2E1 and oxidative liver injury by alcohol
- (2007) Yongke Lu et al. FREE RADICAL BIOLOGY AND MEDICINE
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