Insulin receptor A and Sirtuin 1 synergistically improve learning and spatial memory following chronic salidroside treatment during hypoxia

Salidroside Stimulates Mitochondrial Biogenesis and Protects against H2O2-Induced Endothelial Dysfunction

(2014) Shasha Xing et al.   Oxidative Medicine and Cellular Longevity

Discovery of Novel AKT Inhibitors with Enhanced Anti-Tumor Effects in Combination with the MEK Inhibitor

(2014) Melissa Dumble et al.   PLoS One

SIRT1 Activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease

(2014) Reas S Khan et al.   Acta Neuropathologica Communications

Synthesis and Protective Effects of Novel Salidroside Analogues on Glucose and Serum Depletion Induced Apoptosis in PC12 Cells

(2013) Yahong Zhao et al.   ARCHIV DER PHARMAZIE

Salidroside attenuates beta amyloid-induced cognitive deficits via modulating oxidative stress and inflammatory mediators in rat hippocampus

(2013) Jia Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Resveratrol protects cardiomyocytes from oxidative stress through SIRT1 and mitochondrial biogenesis signaling pathways

(2013) Yong-guang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antioxidant effect of salidroside and its protective effect against furan-induced hepatocyte damage in mice

(2013) Yuan Yuan et al.   Food & Function

Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice

(2012) Hongliang Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Salidroside stimulates the accumulation of HIF-1α protein resulted in the induction of EPO expression: A signaling via blocking the degradation pathway in kidney and liver cells

(2012) Ken Yu-Zhong Zheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation of Nrf2 in primary rat hepatocytes

(2012) M. La Marca et al.   FOOD AND CHEMICAL TOXICOLOGY

Effect of Dietary Macronutrient Composition on AMPK and SIRT1 Expression and Activity in Human Skeletal Muscle

(2012) B. Draznin et al.   HORMONE AND METABOLIC RESEARCH

Neuroglobin Regulates Hypoxic Response of Neuronal Cells through Hif-1α- and Nrf2-mediated Mechanism

(2012) Kalpana B Hota et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Salidroside Protects Human Erythrocytes against Hydrogen Peroxide-Induced Apoptosis

(2012) Erin Wei Qian et al.   JOURNAL OF NATURAL PRODUCTS

Simultaneous Determination of Salidroside and Its Aglycone Metabolite p-Tyrosol in Rat Plasma by Liquid Chromatography-Tandem Mass Spectrometry

(2012) Na Guo et al.   MOLECULES

Huperzine A Ameliorates Cognitive Deficits and Oxidative Stress in the Hippocampus of Rats Exposed to Acute Hypobaric Hypoxia

(2012) Qinghai Shi et al.   NEUROCHEMICAL RESEARCH

Wogonin Improves Histological and Functional Outcomes, and Reduces Activation of TLR4/NF-κB Signaling after Experimental Traumatic Brain Injury

(2012) Chien-Cheng Chen et al.   PLoS One

Nuclear SIRT1 activity, but not protein content, regulates mitochondrial biogenesis in rat and human skeletal muscle

(2011) Brendon J. Gurd et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis

(2011) Ana P. Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Acetyl-L-carnitine-mediated neuroprotection during hypoxia is attributed to ERK1/2-Nrf2-regulated mitochondrial biosynthesis

(2011) Kalpana Barhwal Hota et al.   HIPPOCAMPUS

In vivostimulation of oestrogen receptor α increases insulin-stimulated skeletal muscle glucose uptake

(2011) Brittany K. Gorres et al.   JOURNAL OF PHYSIOLOGY-LONDON

Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy

(2011) L S Steelman et al.   LEUKEMIA

Protective Effect of Salidroside from Rhodiolae Radix on Diabetes-Induced Oxidative Stress in Mice

(2011) Fenglin Li et al.   MOLECULES

Neuroprotective Effects of Salidroside and its Analogue Tyrosol Galactoside Against Focal Cerebral Ischemia In Vivo and H2O2-Induced Neurotoxicity In Vitro

(2011) Tian-yao Shi et al.   NEUROTOXICITY RESEARCH

Salidroside inhibits H2O2-induced apoptosis in PC 12 cells by preventing cytochrome c release and inactivating of caspase cascade

(2010) L. Cai et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Protective Role of Salidroside against Aging in A Mouse Model Induced by D-galactose

(2010) Gen-Xiang MAO et al.   BIOMEDICAL AND ENVIRONMENTAL SCIENCES

Oxidative-stress-induced alterations in Sp factors mediate transcriptional regulation of the NR1 subunit in hippocampus during hypoxia

(2010) Sunil Kumar Hota et al.   FREE RADICAL BIOLOGY AND MEDICINE

Salidroside Attenuates Apoptosis in Ischemic Cardiomyocytes: a Mechanism Through a Mitochondria-Dependent Pathway

(2010) Han Zhong et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

SH2B1 Enhances Insulin Sensitivity by Both Stimulating the Insulin Receptor and Inhibiting Tyrosine Dephosphorylation of Insulin Receptor Substrate Proteins

(2009) D. L. Morris et al.   DIABETES

Cardioprotection of salidroside from ischemia/reperfusion injury by increasing N-acetylglucosamine linkage to cellular proteins

(2009) Tiejun Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effect of salidroside against H2O2-induced cell apoptosis in primary culture of rat hippocampal neurons

(2009) Xia Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Isradipine antagonizes hypobaric hypoxia induced CA1 damage and memory impairment: Complementary roles of L-type calcium channel and NMDA receptors

(2009) Kalpana Barhwal et al.   NEUROBIOLOGY OF DISEASE

Acetyl-l-carnitine (ALCAR) prevents hypobaric hypoxia–induced spatial memory impairment through extracellular related kinase–mediated nuclear factor erythroid 2-related factor 2 phosphorylation

(2009) K. Barhwal et al.   NEUROSCIENCE

Salidroside attenuates glutamate-induced apoptotic cell death in primary cultured hippocampal neurons of rats

(2008) Xia Chen et al.   BRAIN RESEARCH

Hypoxia-induced deactivation of NGF-mediated ERK1/2 signaling in hippocampal cells: Neuroprotection by acetyl-L-carnitine

(2008) Kalpana Barhwal et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Bacopa monniera leaf extract ameliorates hypobaric hypoxia induced spatial memory impairment

(2008) Sunil Kumar Hota et al.   NEUROBIOLOGY OF DISEASE

Ceftriaxone rescues hippocampal neurons from excitotoxicity and enhances memory retrieval in chronic hypobaric hypoxia

(2008) Sunil K. Hota et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Rapidly Increased Neuronal Mitochondrial Biogenesis After Hypoxic-Ischemic Brain Injury

(2008) Wei Yin et al.   STROKE