Diosmin Attenuates Methotrexate-Induced Hepatic, Renal, and Cardiac Injury: A Biochemical and Histopathological Study in Mice
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Title
Diosmin Attenuates Methotrexate-Induced Hepatic, Renal, and Cardiac Injury: A Biochemical and Histopathological Study in Mice
Authors
Keywords
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Journal
Oxidative Medicine and Cellular Longevity
Volume 2017, Issue -, Pages 1-10
Publisher
Hindawi Limited
Online
2017-07-28
DOI
10.1155/2017/3281670
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Note: Only part of the references are listed.- Diosmin induce apoptosis through modulation of STAT-3 signaling in 7,12 dimethylbenz(a)anthracene induced harmster buccal pouch carcinogenesis
- (2016) Muthusamy Rajasekar et al. BIOMEDICINE & PHARMACOTHERAPY
- Effects of quercetin on methotrexate-induced nephrotoxicity in rats
- (2016) Yasemin Yuksel et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Diosmin Modulates the NF-kB Signal Transduction Pathways and Downregulation of Various Oxidative Stress Markers in Alloxan-Induced Diabetic Nephropathy
- (2016) Sahabuddin Ahmed et al. INFLAMMATION
- Protective effect of propolis on methotrexate-induced kidney injury in the rat
- (2016) Hasan Basri Ulusoy et al. RENAL FAILURE
- Does alfa lipoic acid prevent liver from methotrexate induced oxidative injury in rats?
- (2015) Tuğrul Çakır et al. Acta Cirurgica Brasileira
- Diosmin downregulates the expression of T cell receptors, pro-inflammatory cytokines and NF-κB activation against LPS-induced acute lung injury in mice
- (2015) Faisal Imam et al. PHARMACOLOGICAL RESEARCH
- Effects of silymarin on methotrexate-induced nephrotoxicity in rats
- (2015) Durrin Ozlem Dabak et al. RENAL FAILURE
- Diosmin Protects against Ethanol-Induced Gastric Injury in Rats: Novel Anti-Ulcer Actions
- (2015) Hany H. Arab et al. PLoS One
- Diosmin pretreatment improves cardiac function and suppresses oxidative stress in rat heart after ischemia/reperfusion
- (2014) Oomaidurai Senthamizhselvan et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Diosmin protects against cerebral ischemia/reperfusion injury through activating JAK2/STAT3 signal pathway in mice
- (2014) X. Liu et al. NEUROSCIENCE
- Diosmin protects against ethanol-induced hepatic injury via alleviation of inflammation and regulation of TNF-α and NF-κB activation
- (2013) Mir Tahir et al. ALCOHOL
- Diosmin protects against trichloroethylene-induced renal injury in Wistar rats: plausible role of p53, Bax and caspases
- (2013) Muneeb U. Rehman et al. BRITISH JOURNAL OF NUTRITION
- Diosmin exhibits anti-hyperlipidemic effects in isoproterenol induced myocardial infarcted rats
- (2013) S.Sharmila Queenthy et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Pomegranate reverses methotrexate-induced oxidative stress and apoptosis in hepatocytes by modulating Nrf2-NF-κB pathways
- (2013) Sudeshna Mukherjee et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Diosmin abrogates chemically induced hepatocarcinogenesis via alleviation of oxidative stress, hyperproliferative and inflammatory markers in murine model
- (2013) Mir Tahir et al. TOXICOLOGY LETTERS
- Diosmin, a bioflavonoid reverses alterations in blood pressure, nitric oxide, lipid peroxides and antioxidant status in DOCA-salt induced hypertensive rats
- (2012) Thangarasu Silambarasan et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Ameliorative effect of diosmin, a citrus flavonoid against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats
- (2011) Subramani Srinivasan et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways
- (2011) Shiekh Tanveer Ahmad et al. TOXICOLOGY
- The Role of Inflammatory Cytokines in Diabetic Nephropathy
- (2008) J. F. Navarro-Gonzalez et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Inflammation in methotrexate-induced pulmonary toxicity occurs via the p38 MAPK pathway
- (2008) Youn-Jung Kim et al. TOXICOLOGY
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