The Significance of Hypothiocyanite Production via the Pendrin/DUOX/Peroxidase Pathway in the Pathogenesis of Asthma

T follicular helper and T H 2 cells in allergic responses

(2017) Masato Kubo   ALLERGOLOGY INTERNATIONAL

Emerging roles of basophils in allergic inflammation

(2017) Kensuke Miyake et al.   ALLERGOLOGY INTERNATIONAL

The potential for repositioning antithyroid agents as antiasthma drugs

(2016) Shoichi Suzuki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Induction of Airway Allergic Inflammation by Hypothiocyanite via Epithelial Cells

(2016) Shoichi Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial

(2016) Sally Wenzel et al.   LANCET

The prevalence of severe refractory asthma

(2015) Pieter-Paul W. Hekking et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Increased expression of the epithelial anion transporter pendrin/SLC26A4 in nasal polyps of patients with chronic rhinosinusitis

(2015) Sudarshan Seshadri et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Association and management of eosinophilic inflammation in upper and lower airways

(2015) Mitsuhiro Okano et al.   ALLERGOLOGY INTERNATIONAL

Group 2 innate lymphoid cells and asthma

(2015) Hiroki Kabata et al.   ALLERGOLOGY INTERNATIONAL

Recent developments regarding periostin in bronchial asthma

(2015) Kenji Izuhara et al.   ALLERGOLOGY INTERNATIONAL

Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial

(2015) Christopher E Brightling et al.   Lancet Respiratory Medicine

IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy

(2014) Corinne Cayrol et al.   CURRENT OPINION IN IMMUNOLOGY

Interleukin-17 cytokine signalling in patients with asthma

(2014) A. Linden et al.   EUROPEAN RESPIRATORY JOURNAL

Epithelial Anion Transporter Pendrin Contributes to Inflammatory Lung Pathology in Mouse Models of Bordetella pertussis Infection

(2014) Karen M. Scanlon et al.   INFECTION AND IMMUNITY

Identification of Pendrin as a Common Mediator for Mucus Production in Bronchial Asthma and Chronic Obstructive Pulmonary Disease

(2014) Isao Nakao et al.   JOURNAL OF IMMUNOLOGY

The Epithelial Anion Transporter Pendrin Is Induced by Allergy and Rhinovirus Infection, Regulates Airway Surface Liquid, and Increases Airway Reactivity and Inflammation in an Asthma Model

(2014) Y. Nakagami et al.   JOURNAL OF IMMUNOLOGY

Intratracheal instillation of single-wall carbon nanotubes in the rat lung induces time-dependent changes in gene expression

(2014) Katsuhide Fujita et al.   Nanotoxicology

IL-17A Induces Pendrin Expression and Chloride-Bicarbonate Exchange in Human Bronchial Epithelial Cells

(2014) Kelly M. Adams et al.   PLoS One

Cytokine inhibition in the treatment of COPD

(2014) Kian Fan Chung et al.   International Journal of Chronic Obstructive Pulmonary Disease

IL-1β expression in the distal lung epithelium disrupts lung morphogenesis and epithelial cell differentiation in fetal mice

(2013) Anna Hogmalm et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Human Pendrin Promoter Contains two N4GAS Motifs with Different Functional Relevance

(2013) Simone Vanoni et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

T Helper 17 Cells in Airway Diseases

(2013) Rabih Halwani et al.   CHEST

Transcriptome sequencing (RNA-Seq) of human endobronchial biopsies: asthmaversuscontrols

(2013) Ching Yong Yick et al.   EUROPEAN RESPIRATORY JOURNAL

Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma

(2013) Michael C. Peters et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Smoking and asthma: dangerous liaisons

(2012) Riccardo Polosa et al.   EUROPEAN RESPIRATORY JOURNAL

Pertussis Toxin Exacerbates and Prolongs Airway Inflammatory Responses during Bordetella pertussis Infection

(2012) Carey E. Connelly et al.   INFECTION AND IMMUNITY

Molecular insights into the progression of crystalline silica-induced pulmonary toxicity in rats

(2012) Rajendran Sellamuthu et al.   JOURNAL OF APPLIED TOXICOLOGY

Expression of Pendrin Periostin in Allergic Rhinitis Chronic Rhinosinusitis

(2012) Akihiro Ishida et al.   ALLERGOLOGY INTERNATIONAL

Hypothiocyanous Acid: Benign or Deadly?

(2011) Tessa J. Barrett et al.   CHEMICAL RESEARCH IN TOXICOLOGY

STAT6 Links IL-4/IL-13 Stimulation With Pendrin Expression in Asthma and Chronic Obstructive Pulmonary Disease

(2011) C Nofziger et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The effects of cigarette smoke on airway inflammation in asthma and COPD: Therapeutic implications

(2011) Asad Tamimi et al.   RESPIRATORY MEDICINE

Inflammatory response in rat lungs with recurrent exposure to welding fumes

(2011) Jung-Hwa Oh et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Identification of potential biomarkers from gene expression profiles in rat lungs intratracheally instilled with C60 fullerenes

(2010) Katsuhide Fujita et al.   TOXICOLOGY

The value of drug repositioning in the current pharmaceutical market

(2009) E.L. Tobinick   DRUG NEWS & PERSPECTIVES

The role of hypothiocyanous acid (HOSCN) in biological systems

(2009) Clare L. Hawkins   FREE RADICAL RESEARCH

New asthma biomarkers: lessons from murine models of acute and chronic asthma

(2008) Emmanuel Di Valentin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY