Protein Glutathionylation in the Pathogenesis of Neurodegenerative Diseases

Regulation of DJ-1 by Glutaredoxin 1 in Vivo: Implications for Parkinson’s Disease

(2016) William M. Johnson et al.   BIOCHEMISTRY

The contribution of alpha synuclein to neuronal survival and function - Implications for Parkinson's disease

(2016) Matthew J. Benskey et al.   JOURNAL OF NEUROCHEMISTRY

Decoding ALS: from genes to mechanism

(2016) J. Paul Taylor et al.   NATURE

Dysregulation of autophagy and mitochondrial function in Parkinson’s disease

(2016) Bao Wang et al.   Translational Neurodegeneration

Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases

(2015) Olga Gorelenkova Miller et al.   ARCHIVES OF TOXICOLOGY

Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington’s disease

(2015) Chansik Hong et al.   BRAIN

Development of a Clickable Probe for Profiling of Protein Glutathionylation in the Central Cellular Metabolism of E. coli and Drosophila

(2015) Shan Feng et al.   CHEMISTRY & BIOLOGY

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

(2015) Alicia M. Pickrell et al.   NEURON

Amyotrophic lateral sclerosis: Current perspectives from basic research to the clinic

(2015) Renzo Mancuso et al.   PROGRESS IN NEUROBIOLOGY

Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions

(2015) Natalie E. Farrawell et al.   Scientific Reports

The physiology and pathology of microtubule-associated protein tau

(2014) Jian-Zhi Wang et al.   Essays in Biochemistry

Oxidized DJ-1 as a possible biomarker of Parkinson’s disease

(2014) Yoshiro Saito   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Huntington disease: natural history, biomarkers and prospects for therapeutics

(2014) Christopher A. Ross et al.   Nature Reviews Neurology

Glutathione and mitochondria

(2014) Vicent Ribas et al.   Frontiers in Pharmacology

Protein glutathionylation in health and disease

(2013) Pietro Ghezzi   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glutathione is essential to preserve nuclear function and cell survival under oxidative stress

(2013) Elie Hatem et al.   FREE RADICAL BIOLOGY AND MEDICINE

Aberrant Protein S-Nitrosylation in Neurodegenerative Diseases

(2013) Tomohiro Nakamura et al.   NEURON

Nuclear glutathione

(2012) José Luis García-Giménez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glutathione synthesis

(2012) Shelly C. Lu   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

GlutathioneS-Transferase Omega 1 Activity Is Sufficient to Suppress Neurodegeneration in aDrosophilaModel of Parkinson Disease

(2012) Kiyoung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dysregulation of Mitochondrial Calcium Signaling and Superoxide Flashes Cause Mitochondrial Genomic DNA Damage in Huntington Disease

(2012) Jiu-Qiang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

(2012) David N. Hauser et al.   NEUROBIOLOGY OF DISEASE

Mechanisms of Altered Redox Regulation in Neurodegenerative Diseases—Focus on S-Glutathionylation

(2011) Elizabeth A. Sabens Liedhegner et al.   ANTIOXIDANTS & REDOX SIGNALING

Protein aggregates in Huntington's disease

(2011) Montserrat Arrasate et al.   EXPERIMENTAL NEUROLOGY

The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons

(2011) Wendou Yu et al.   HUMAN MOLECULAR GENETICS

Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance

(2011) B. Heeman et al.   JOURNAL OF CELL SCIENCE

Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders

(2011) Karen M. Doyle et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A yeast functional screen predicts new candidate ALS disease genes

(2011) J. Couthouis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cys-141 glutathionylation of human p53: Studies using specific polyclonal antibodies in cancer samples and cell lines

(2010) Mohd. A. Yusuf et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of glutathione in cell nucleus

(2010) Jelena Markovic et al.   FREE RADICAL RESEARCH

Palmitoylation and depalmitoylation dynamics at a glance

(2010) Elizabeth Conibear et al.   JOURNAL OF CELL SCIENCE

Cytoplasmic Mislocalization of TDP-43 Is Toxic to Neurons and Enhanced by a Mutation Associated with Familial Amyotrophic Lateral Sclerosis

(2010) S. J. Barmada et al.   JOURNAL OF NEUROSCIENCE

Protein palmitoylation in neuronal development and synaptic plasticity

(2010) Yuko Fukata et al.   NATURE REVIEWS NEUROSCIENCE

Glutathione dysregulation and the etiology and progression of human diseases

(2009) Nazzareno Ballatori et al.   BIOLOGICAL CHEMISTRY

Modifications of Superoxide Dismutase (SOD1) in Human Erythrocytes

(2009) Kyle C. Wilcox et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle

(2009) Kristen A Malkus et al.   Molecular Neurodegeneration

Glutathionylation of the Pro-apoptotic Protein p53 in Alzheimer’s Disease Brain: Implications for AD Pathogenesis

(2009) Fabio Di Domenico et al.   NEUROCHEMICAL RESEARCH

Complex I within Oxidatively Stressed Bovine Heart Mitochondria Is Glutathionylated on Cys-531 and Cys-704 of the 75-kDa Subunit

(2008) Thomas R. Hurd et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ischemia Enhances Activation by Ca2+ and Redox Modification of Ryanodine Receptor Channels from Rat Brain Cortex

(2008) R. Bull et al.   JOURNAL OF NEUROSCIENCE

DJ-1 Modulates α-Synuclein Aggregation State in a Cellular Model of Oxidative Stress: Relevance for Parkinson's Disease and Involvement of HSP70

(2008) Sara Batelli et al.   PLoS One

Amyotrophic Lateral Sclerosis: From Current Developments in the Laboratory to Clinical Implications

(2007) Mauro Cozzolino et al.   ANTIOXIDANTS & REDOX SIGNALING

Reversible Inhibition of α-Ketoglutarate Dehydrogenase by Hydrogen Peroxide:  Glutathionylation and Protection of Lipoic Acid†

(2007) Milana A. B. Applegate et al.   BIOCHEMISTRY