Expression of the NRF2 Target Gene NQO1 Is Enhanced in Mononuclear Cells in Human Chronic Kidney Disease

Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression

(2017) Masahiro Nezu et al.   KIDNEY INTERNATIONAL

Renal recruitment of B lymphocytes exacerbates tubulointerstitial fibrosis by promoting monocyte mobilization and infiltration after unilateral ureteral obstruction

(2016) Hui Han et al.   JOURNAL OF PATHOLOGY

Lower Superoxide Dismutase 2 (SOD2) Protein Content in Mononuclear Cells Is Associated with Better Survival in Patients with Hemodialysis Therapy

(2016) Katharina Krueger et al.   Oxidative Medicine and Cellular Longevity

Effects of aged garlic extract and FruArg on gene expression and signaling pathways in lipopolysaccharide-activated microglial cells

(2016) Hailong Song et al.   Scientific Reports

Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress

(2015) Fiona E. Mutter et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Nrf2-mediated adaptive response to methyl glyoxal in HepG2 cells involves the induction of AKR7A2

(2015) Dan Li et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Molecular basis of the Keap1–Nrf2 system

(2015) Takafumi Suzuki et al.   FREE RADICAL BIOLOGY AND MEDICINE

T Lymphocyte-Specific Activation of Nrf2 Protects from AKI

(2015) S. Noel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney

(2015) Luke M. Shelton et al.   KIDNEY INTERNATIONAL

Reviving the promise of transcription factor Nrf2-based therapeutics for kidney diseases

(2015) Sanjeev Noel et al.   KIDNEY INTERNATIONAL

Innate immunity in CKD-associated vascular diseases

(2015) Stephen Zewinger et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Role of Nrf2 Dysfunction in Uremia-Associated Intestinal Inflammation and Epithelial Barrier Disruption

(2014) Wei Ling Lau et al.   DIGESTIVE DISEASES AND SCIENCES

Risk Factors for Heart Failure in Patients With Type 2 Diabetes Mellitus and Stage 4 Chronic Kidney Disease Treated With Bardoxolone Methyl

(2014) Melanie P. Chin et al.   JOURNAL OF CARDIAC FAILURE

Keap1 inhibition attenuates glomerulosclerosis

(2014) Yoichi Miyazaki et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease

(2013) Dick de Zeeuw et al.   NEW ENGLAND JOURNAL OF MEDICINE

Indoxyl sulfate, a uremic toxin, downregulates renal expression of Nrf2 through activation of NF-κB

(2013) Dilinaer Bolati et al.   BMC Nephrology

A Phase I First-in-Human Trial of Bardoxolone Methyl in Patients with Advanced Solid Tumors and Lymphomas

(2012) D. S. Hong et al.   CLINICAL CANCER RESEARCH

Notice

(2012)   Kidney International Supplements

Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes

(2011) Pablo E. Pergola et al.   NEW ENGLAND JOURNAL OF MEDICINE

Superoxide dismutase type 1 in monocytes of chronic kidney disease patients

(2010) Alexandra Scholze et al.   AMINO ACIDS

Atherosclerosis in chronic kidney disease: the role of macrophages

(2010) Valentina Kon et al.   Nature Reviews Nephrology

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY