α-Halo carbonyls enable meta selective primary, secondary and tertiary C–H alkylations by ruthenium catalysis

Ruthenium(II)-catalysed remote C–H alkylations as a versatile platform to meta-decorated arenes

(2017) Jie Li et al.   Nature Communications

Ligand-Enabled Regioselectivity in the Oxidative Cross-coupling of Arenes with Toluenes and Cycloalkanes Using Ruthenium Catalysts: Tuning the Site-Selectivity from the ortho to meta Positions

(2017) Guobao Li et al.   ACS Catalysis

Remote C6-Selective Ruthenium-Catalyzed C–H Alkylation of Indole Derivatives via σ-Activation

(2017) Jamie A. Leitch et al.   ACS Catalysis

Ruthenium(II)-Catalyzed Decarboxylative C−H Activation: Versatile Routes tometa-Alkenylated Arenes

(2016) N. Y. Phani Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sequential meta-C–H olefination of synthetically versatile benzyl silanes: effective synthesis of meta-olefinated toluene, benzaldehyde and benzyl alcohols

(2016) Tuhin Patra et al.   CHEMICAL COMMUNICATIONS

Ligand-Promoted meta-C–H Amination and Alkynylation

(2016) Peng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Promoted Meta-C–H Arylation of Anilines, Phenols, and Heterocycles

(2016) Peng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand Promoted meta-C–H Chlorination of Anilines and Phenols

(2016) Hang Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ion Pair-Directed Regiocontrol in Transition-Metal Catalysis: A Meta-Selective C–H Borylation of Aromatic Quaternary Ammonium Salts

(2016) Holly J. Davis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Meta-Selective CAr–H Nitration of Arenes through a Ru3(CO)12-Catalyzed Ortho-Metalation Strategy

(2016) Zhoulong Fan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Charge-transfer-directed radical substitution enables para-selective C–H functionalization

(2016) Gregory B. Boursalian et al.   Nature Chemistry

Pd(II)-catalysed meta-C–H functionalizations of benzoic acid derivatives

(2016) Shangda Li et al.   Nature Communications

Room-Temperature meta-Functionalization: Pd(II)-Catalyzed Synthesis of 1,3,5-Trialkenyl Arene and meta-Hydroxylated Olefin

(2016) Milan Bera et al.   ACS Catalysis

Mechanistic insight into ruthenium catalysed meta-sulfonation of 2-phenylpyridine

(2016) Patricia Marcé et al.   Catalysis Science & Technology

Palladium(II)-Catalyzedmeta-CH Olefination: Constructing Multisubstituted Arenes through Homo-Diolefination and Sequential Hetero-Diolefination

(2015) Milan Bera et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Directedmeta-Selective Bromination of Arenes with Ruthenium Catalysts

(2015) Qingzhen Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium-Catalyzedmeta-Selective CH Bromination

(2015) Christopher J. Teskey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic meta-selective C–H functionalization to construct quaternary carbon centres

(2015) Andrew J. Paterson et al.   CHEMICAL COMMUNICATIONS

Salicylic acids as readily available starting materials for the synthesis of meta-substituted biaryls

(2015) Junfei Luo et al.   CHEMICAL COMMUNICATIONS

A Domino Oxidation/Arylation/Protodecarboxylation Reaction of Salicylaldehydes: Expanded Access tometa-Arylphenols

(2015) Junfei Luo et al.   Chemistry-An Asian Journal

N-Acyl Amino Acid Ligands for Ruthenium(II)-Catalyzed meta-C–H tert-Alkylation with Removable Auxiliaries

(2015) Jie Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Versatile Enantioselective Synthesis of Functionalized Lactones via Copper-Catalyzed Radical Oxyfunctionalization of Alkenes

(2015) Rong Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Enabled Meta-C–H Alkylation and Arylation Using a Modified Norbornene

(2015) Peng-Xiang Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Simple Amine-Directed Meta-Selective C–H Arylation via Pd/Norbornene Catalysis

(2015) Zhe Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-enabled meta-C–H activation using a transient mediator

(2015) Xiao-Chen Wang et al.   NATURE

A meta-selective C–H borylation directed by a secondary interaction between ligand and substrate

(2015) Yoichiro Kuninobu et al.   Nature Chemistry

Transition metal catalyzed meta-C–H functionalization of aromatic compounds

(2015) Jiong Yang   ORGANIC & BIOMOLECULAR CHEMISTRY

Pd(ii)-catalyzed remote regiodivergent ortho- and meta-C–H functionalizations of phenylethylamines

(2015) Shangda Li et al.   Chemical Science

Cobalt-Catalyzed C–H Activation

(2015) Marc Moselage et al.   ACS Catalysis

Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups

(2015) Zhengkai Chen et al.   Organic Chemistry Frontiers

Remote Meta-C–H Activation Using a Pyridine-Based Template: Achieving Site-Selectivity via the Recognition of Distance and Geometry

(2015) Ling Chu et al.   ACS Central Science

Remotemeta-CH Olefination of Phenylacetic Acids Directed by a Versatile U-Shaped Template

(2014) Youqian Deng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed olefinic C–H difluoroacetylation of enamides

(2014) Gilles Caillot et al.   CHEMICAL COMMUNICATIONS

Overriding Ortho–Para Selectivity via a Traceless Directing Group Relay Strategy: The Meta-Selective Arylation of Phenols

(2014) Junfei Luo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzed meta-C–H Olefination, Arylation, and Acetoxylation of Indolines Using a U-Shaped Template

(2014) Guoqiang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-catalysed direct radical alkenylation of alkyl bromides

(2014) Xu Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Meta-Selective Arene C–H Bond Olefination of Arylacetic Acid Using a Nitrile-Based Directing Group

(2014) Milan Bera et al.   ORGANIC LETTERS

Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C–H/Het–H Bond Functionalizations

(2013) Lutz Ackermann   ACCOUNTS OF CHEMICAL RESEARCH

Pd(II)-Catalyzed ortho- or meta-C–H Olefination of Phenol Derivatives

(2013) Hui-Xiong Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Meta-Selective C–H Functionalization Using a Nitrile-Based Directing Group and Cleavable Si-Tether

(2013) Sunggi Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cross-Coupling of Remote meta-C–H Bonds Directed by a U-Shaped Template

(2013) Li Wan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

meta-Selective C–H Bond Alkylation with Secondary Alkyl Halides

(2013) Nora Hofmann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Efficient Generation of a Functionalized Tertiary-Alkyl Radical for Copper-catalyzed Tertiary-Alkylative Mizoroki-Heck type Reaction

(2013) Takashi Nishikata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

(2012) Junichiro Yamaguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization

(2012) Percia Beatrice Arockiam et al.   CHEMICAL REVIEWS

CH Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products

(2012) David Y.-K. Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Activation of remote meta-C–H bonds assisted by an end-on template

(2012) Dasheng Leow et al.   NATURE

Rhodium Catalyzed Chelation-Assisted C–H Bond Functionalization Reactions

(2011) Denise A. Colby et al.   ACCOUNTS OF CHEMICAL RESEARCH

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Carboxylic Acids as Traceless Directing Groups for Formal meta-Selective Direct Arylation

(2011) Josep Cornella et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

Ruthenium-Catalyzed Meta Sulfonation of 2-Phenylpyridines

(2011) Ourida Saidi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Autocatalysis for C–H Bond Activation by Ruthenium(II) Complexes in Catalytic Arylation of Functional Arenes

(2011) Emmanuel Ferrer Flegeau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carboxylate-Assisted Ruthenium-Catalyzed Direct Alkylations of Ketimines

(2011) Lutz Ackermann et al.   ORGANIC LETTERS

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Ruthenium-Catalyzed Regioselective Direct Alkylation of Arenes with Unactivated Alkyl Halides through CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assisted Ruthenium-Catalyzed C−H Bond Activation: Carboxylic Acids as Cocatalysts for Generally Applicable Direct Arylations in Apolar Solvents

(2008) Lutz Ackermann et al.   ORGANIC LETTERS