Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA

13-Series resolvins mediate the leukocyte-platelet actions of atorvastatin and pravastatin in inflammatory arthritis

(2017) Mary E. Walker et al.   FASEB JOURNAL

Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution

(2017) Jesmond Dalli et al.   IMMUNITY

Does promoting resolution instead of inhibiting inflammation represent the new paradigm in treating infections?

(2017) Jesmond Dalli   MOLECULAR ASPECTS OF MEDICINE

Protectin D1n-3 DPAand resolvin D5n-3 DPAare effectors of intestinal protection

(2017) Thomas Gobbetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The novel lipid mediator PD1 n-3 DPA : An overview of the structural elucidation, synthesis, biosynthesis and bioactions

(2017) Trond Vidar Hansen et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

First total synthesis of pro-resolving and tissue-regenerative resolvin sulfido-conjugates

(2017) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation

(2016) Sesquile Ramon et al.   AMERICAN JOURNAL OF PATHOLOGY

Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins

(2016) Karoline G. Primdahl et al.   JOURNAL OF NATURAL PRODUCTS

Resolution of inflammation: a new therapeutic frontier

(2016) James N. Fullerton et al.   NATURE REVIEWS DRUG DISCOVERY

Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages

(2016) Jesmond Dalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3

(2016) Jesmond Dalli et al.   PLoS One

Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways

(2015) Jesmond Dalli et al.   FASEB JOURNAL

Synthesis of the 16S,17S-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages

(2015) Marius Aursnes et al.   JOURNAL OF NATURAL PRODUCTS

Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections

(2015) Jesmond Dalli et al.   NATURE MEDICINE

First total synthesis of pro-resolving and tissue-regenerative Maresin sulfido-conjugates

(2015) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

Total synthesis of pro-resolving and tissue-regenerative Protectin sulfido-conjugates

(2015) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

Total Synthesis of the Lipid Mediator PD1n-3 DPA: Configurational Assignments and Anti-inflammatory and Pro-resolving Actions

(2014) Marius Aursnes et al.   JOURNAL OF NATURAL PRODUCTS

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection

(2014) J. Dalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5-Lipoxygenase inhibitors: a review of recent patents (2010 – 2012)

(2013) Bettina Hofmann et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype

(2013) Jesmond Dalli et al.   FASEB JOURNAL

Stereoselective synthesis of protectin D1: a potent anti-inflammatory and proresolving lipid mediator

(2013) M. Aursnes et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Novel n-3 Immunoresolvents: Structures and Actions

(2013) Jesmond Dalli et al.   Scientific Reports

Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors

(2012) Burcu Çalışkan et al.   Expert Opinion on Drug Discovery

Resolvins and Protectins in Inflammation Resolution

(2011) Charles N. Serhan et al.   CHEMICAL REVIEWS

Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation

(2011) Sungwhan F. Oh et al.   JOURNAL OF CLINICAL INVESTIGATION

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

(2008) Charles N. Serhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus

(2007) C N Serhan et al.   BRITISH JOURNAL OF PHARMACOLOGY