Histone methyltransferase KMT2D sustains prostate carcinogenesis and metastasis via epigenetically activating LIFR and KLF4

Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2 : CALGB 151111 (Alliance)

(2017) Arnaud Augert et al.   Journal of Thoracic Oncology

Genomic hallmarks of localized, non-indolent prostate cancer

(2017) Michael Fraser et al.   NATURE

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma

(2016) J. B. N. Dawkins et al.   CANCER RESEARCH

Genetic Progression of High Grade Prostatic Intraepithelial Neoplasia to Prostate Cancer

(2016) Seung-Hyun Jung et al.   EUROPEAN UROLOGY

Mutation of cancer driverMLL2results in transcription stress and genome instability

(2016) Theodoros Kantidakis et al.   GENES & DEVELOPMENT

MLL2 is essential for porcine embryo development in vitro

(2016) Ming-Hui Zhao et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Comparative transcriptome analysis of chemosensory genes in two sister leaf beetles provides insights into chemosensory speciation

(2016) Bin Zhang et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Integrative Clinical Genomics of Advanced Prostate Cancer

(2015) Dan Robinson et al.   CELL

The Molecular Taxonomy of Primary Prostate Cancer

(2015) Adam Abeshouse et al.   CELL

Assessing Copy Number Alterations in Targeted, Amplicon-Based Next-Generation Sequencing Data

(2015) Catherine Grasso et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis

(2015) Jiyuan Zhang et al.   NATURE MEDICINE

The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development

(2015) Ana Ortega-Molina et al.   NATURE MEDICINE

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

The cancer COMPASS: navigating the functions of MLL complexes in cancer

(2015) David J. Ford et al.   Cancer Genetics

Cis-regulatory somatic mutations and gene-expression alteration in B-cell lymphomas

(2015) Anthony Mathelier et al.   GENOME BIOLOGY

Prostate cancer in Asian men

(2014) Kazuto Ito   Nature Reviews Urology

A Novel 3-Dimensional Image Analysis System for Case-specific Kidney Anatomy and Surgical Simulation to Facilitate Clampless Partial Nephrectomy

(2014) Yoshinobu Komai et al.   UROLOGY

Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance

(2013) Shu-Chen Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Advancing Precision Medicine for Prostate Cancer Through Genomics

(2013) Sameek Roychowdhury et al.   JOURNAL OF CLINICAL ONCOLOGY

Modification of Enhancer Chromatin: What, How, and Why?

(2013) Eliezer Calo et al.   MOLECULAR CELL

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

(2012) Christopher E Barbieri et al.   NATURE GENETICS

Cutoff Finder: A Comprehensive and Straightforward Web Application Enabling Rapid Biomarker Cutoff Optimization

(2012) Jan Budczies et al.   PLoS One

Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways

(2012) C. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets

(2012) Zhen Shao et al.   GENOME BIOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

HOXC6 Is Transcriptionally Regulated via Coordination of MLL Histone Methylase and Estrogen Receptor in an Estrogen Environment

(2011) Khairul I. Ansari et al.   JOURNAL OF MOLECULAR BIOLOGY

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Distinct Genomic Alterations in Prostate Cancers in Chinese and Western Populations Suggest Alternative Pathways of Prostate Carcinogenesis

(2010) X. Mao et al.   CANCER RESEARCH

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

A clustering approach for identification of enriched domains from histone modification ChIP-Seq data

(2009) Chongzhi Zang et al.   BIOINFORMATICS

SOAP2: an improved ultrafast tool for short read alignment

(2009) R. Li et al.   BIOINFORMATICS

Allelic imbalance (AI) identifies novel tissue-specificcis-regulatory variation for humanUGT2B15

(2009) Chang Sun et al.   HUMAN MUTATION

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols