Targeting nuclear receptors in cancer-associated fibroblasts as concurrent therapy to inhibit development of chemoresistant tumors

Cancer-associated Fibroblasts Promote Irradiated Cancer Cell Recovery Through Autophagy

(2017) Yongbin Wang et al.   EBioMedicine

Nuclear receptor function in skin health and disease: therapeutic opportunities in the orphan and adopted receptor classes

(2016) Kelvin Yin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interleukin-6: A Critical Cytokine in Cancer Multidrug Resistance

(2016) Morteza Ghandadi et al.   CURRENT PHARMACEUTICAL DESIGN

Carcinoma-associated fibroblasts: orchestrating the composition of malignancy

(2016) Philippe Gascard et al.   GENES & DEVELOPMENT

Stromal contributions to the carcinogenic process

(2016) Mark Spaw et al.   MOLECULAR CARCINOGENESIS

Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets

(2016) Yufang Shi et al.   NATURE REVIEWS DRUG DISCOVERY

Carcinogenesis explained within the context of a theory of organisms

(2016) Carlos Sonnenschein et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Transcriptional control of physiological and pathological processes by the nuclear receptor PPARβ/δ

(2016) Nguan Soon Tan et al.   PROGRESS IN LIPID RESEARCH

The myofibroblast, a key cell in normal and pathological tissue repair

(2015) Ian A. Darby et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

COL11A1/(pro)collagen 11A1 expression is a remarkable biomarker of human invasive carcinoma-associated stromal cells and carcinoma progression

(2015) Fernando Vázquez-Villa et al.   TUMOR BIOLOGY

Tumors: Wounds That Do Not Heal--Redux

(2015) H. F. Dvorak   Cancer Immunology Research

Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy

(2014) Mara H. Sherman et al.   CELL

The role of nuclear hormone receptors in cutaneous wound repair

(2014) Sandra Rieger et al.   CELL BIOCHEMISTRY AND FUNCTION

PDGF receptors in tumor biology: prognostic and predictive potential

(2014) Janna Paulsson et al.   Future Oncology

All-trans retinoic acid attenuates experimental colitis through inhibition of NF-κB signaling

(2014) Kai Hong et al.   IMMUNOLOGY LETTERS

Tranilast Inhibits the Function of Cancer-Associated Fibroblasts Responsible for the Induction of Immune Suppressor Cell Types

(2014) Y. Ohshio et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Tumor and the Microenvironment: A Chance to Reframe the Paradigm of Carcinogenesis?

(2014) Mariano Bizzarri et al.   Biomed Research International

Wounds That Will Not Heal

(2013) Jung S. Byun et al.   AMERICAN JOURNAL OF PATHOLOGY

Synergistic Targeting of PI3K/AKT Pathway and Androgen Receptor Axis Significantly Delays Castration-Resistant Prostate Cancer ProgressionIn Vivo

(2013) Christian Thomas et al.   MOLECULAR CANCER THERAPEUTICS

Effect of Small Molecules Modulating Androgen Receptor (SARMs) in Human Prostate Cancer Models

(2013) Anna Tesei et al.   PLoS One

Loss of TAK1 increases cell traction force in a ROS-dependent manner to drive epithelial–mesenchymal transition of cancer cells

(2013) C R I Lam et al.   Cell Death & Disease

Overexpression of periostin predicts poor prognosis in non-small cell lung cancer

(2013) LING-ZHI HONG et al.   Oncology Letters

Carcinoma-Associated Fibroblasts Are a Promising Therapeutic Target

(2013) Shinsaku Togo et al.   Cancers

Understanding the "lethal" drivers of tumor-stroma co-evolution

(2010) Michael P. Lisanti et al.   CANCER BIOLOGY & THERAPY

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

(2009) Angélica M. Santos et al.   JOURNAL OF CLINICAL INVESTIGATION

Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation

(2009) Serge A van de Pavert et al.   NATURE IMMUNOLOGY

Tranilast inhibits hormone refractory prostate cancer cell proliferation and suppresses transforming growth factor β1-associated osteoblastic changes

(2009) Kouji Izumi et al.   PROSTATE

Defining and targeting transcription factors in cancer

(2009) Aisling M Redmond et al.   GENOME BIOLOGY