Nuclear receptor function in skin health and disease: therapeutic opportunities in the orphan and adopted receptor classes
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Nuclear receptor function in skin health and disease: therapeutic opportunities in the orphan and adopted receptor classes
Authors
Keywords
Nuclear receptor, Wound healing, Orphan receptors, PPAR, LXR, NR4A
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 73, Issue 20, Pages 3789-3800
Publisher
Springer Nature
Online
2016-08-20
DOI
10.1007/s00018-016-2329-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Nuclear receptor 4A (NR4A) family – orphans no more
- (2016) Stephen Safe et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Pseudoceramide stimulates peroxisome proliferator-activated receptor-α expression in a murine model of atopic dermatitis: molecular basis underlying the anti-inflammatory effect and the preventive effect against steroid-induced barrier impairment
- (2015) Sang Eun Lee et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- Skin response to a carcinogen involves the xenobiotic receptor pregnane X receptor
- (2015) Andreas Elentner et al. EXPERIMENTAL DERMATOLOGY
- Orphan nuclear receptor TR3/Nur77 improves wound healing by upregulating the expression of integrin β4
- (2015) Gengming Niu et al. FASEB JOURNAL
- Stimulation of PPARα normalizes the skin lipid ratio and improves the skin barrier of normal and filaggrin deficient reconstructed skin
- (2015) Leonie Wallmeyer et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Macrophage PPARγ and impaired wound healing in type 2 diabetes
- (2015) Rita E Mirza et al. JOURNAL OF PATHOLOGY
- Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis
- (2015) Katrin Palumbo-Zerr et al. NATURE MEDICINE
- The dark side of sunlight and melanoma
- (2015) J.-S. Taylor SCIENCE
- Liver X receptor activation induces apoptosis of melanoma cell through caspase pathway
- (2014) Wenjun Zhang et al. Cancer Cell International
- Broad-Spectrum Therapeutic Suppression of Metastatic Melanoma through Nuclear Hormone Receptor Activation
- (2014) Nora Pencheva et al. CELL
- The role of nuclear hormone receptors in cutaneous wound repair
- (2014) Sandra Rieger et al. CELL BIOCHEMISTRY AND FUNCTION
- The Therapeutic Potential of Nuclear Receptor Modulators for Treatment of Metabolic Disorders: PPARγ, RORs, and Rev-erbs
- (2014) David P. Marciano et al. Cell Metabolism
- Function of transcription factors at DNA lesions in DNA repair
- (2014) Michal Malewicz et al. EXPERIMENTAL CELL RESEARCH
- Pharmacologic Inhibition of ROR t Regulates Th17 Signature Gene Expression and Suppresses Cutaneous Inflammation In Vivo
- (2014) J. Skepner et al. JOURNAL OF IMMUNOLOGY
- The NR4A orphan nuclear receptors: mediators in metabolism and diseases
- (2014) Harmit S. Ranhotra JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Activation of pregnane X receptor inhibits experimental dermal fibrosis
- (2013) Christian Beyer et al. ANNALS OF THE RHEUMATIC DISEASES
- Role of lipids in the formation and maintenance of the cutaneous permeability barrier
- (2013) Kenneth R. Feingold et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The important role of stratum corneum lipids for the cutaneous barrier function
- (2013) J. van Smeden et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Diabetes induces stable intrinsic changes to myeloid cells that contribute to chronic inflammation during wound healing in mice
- (2013) P. Bannon et al. Disease Models & Mechanisms
- Preclinical Studies of a Specific PPARγ Modulator in the Control of Skin Inflammation
- (2013) Arianna Mastrofrancesco et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- In Vivo Induction of Cutaneous Inflammation Results in the Accumulation of Extracellular Trap-Forming Neutrophils Expressing RORγt and IL-17
- (2013) Romy R.M.C Keijsers et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions
- (2013) Andrzej T. Slominski et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- A melanocyte lineage program confers resistance to MAP kinase pathway inhibition
- (2013) Cory M. Johannessen et al. NATURE
- Chemoprevention of Skin Cancer with 1,1-Bis (3′-Indolyl)-1-(Aromatic) Methane Analog through Induction of the Orphan Nuclear Receptor, NR4A2 (Nurr1)
- (2013) Cedar H. A. Boakye et al. PLoS One
- The Retinoid-Related Orphan Receptor RORα Promotes Keratinocyte Differentiation via FOXN1
- (2013) Jun Dai et al. PLoS One
- The NR4A2 Nuclear Receptor Is Recruited to Novel Nuclear Foci in Response to UV Irradiation and Participates in Nucleotide Excision Repair
- (2013) Kasturee Jagirdar et al. PLoS One
- Cholesterol sulfate induces expression of the skin barrier protein filaggrin in normal human epidermal keratinocytes through induction of RORα
- (2012) Osamu Hanyu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3′-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cells
- (2012) Xi Li et al. BIOCHEMICAL PHARMACOLOGY
- Molecular Pathways: The Role of NR4A Orphan Nuclear Receptors in Cancer
- (2012) H. M. Mohan et al. CLINICAL CANCER RESEARCH
- Small molecule inhibitors of RORγt: Targeting Th17 cells and other applications
- (2012) Jun R. Huh et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Skin-Targeted Inhibition of PPAR β/δ by Selective Antagonists to Treat PPAR β/δ – Mediated Psoriasis-Like Skin Disease In Vivo
- (2012) Katrin Hack et al. PLoS One
- Action of RORs and their ligands in (patho)physiology
- (2012) Laura A. Solt et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- PPARs at the crossroads of lipid signaling and inflammation
- (2012) Walter Wahli et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Dysregulation of monocyte/macrophage phenotype in wounds of diabetic mice
- (2011) Rita Mirza et al. CYTOKINE
- Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair
- (2011) M. Malewicz et al. GENES & DEVELOPMENT
- Atopic dermatitis: a disease of altered skin barrier and immune dysregulation
- (2011) Mark Boguniewicz et al. IMMUNOLOGICAL REVIEWS
- Efficacy of Combined Peroxisome Proliferator-Activated Receptor-α Ligand and Glucocorticoid Therapy in a Murine Model of Atopic Dermatitis
- (2011) Yutaka Hatano et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Regulation of NR4A nuclear receptor expression by oncogenic BRAF in melanoma cells
- (2011) Aaron G. Smith et al. Pigment Cell & Melanoma Research
- Pathobiology of Chronic Inflammatory Skin Diseases: Interplay Between Keratinocytes and Immune Cells as a Target for Anti-Inflammatory Drugs
- (2010) C. Albanesi et al. CURRENT DRUG METABOLISM
- Review: Ultraviolet radiation and skin cancer
- (2010) Deevya L. Narayanan et al. INTERNATIONAL JOURNAL OF DERMATOLOGY
- Differential Roles of Macrophages in Diverse Phases of Skin Repair
- (2010) T. Lucas et al. JOURNAL OF IMMUNOLOGY
- Activation of PPARβ/δ Causes a Psoriasis-Like Skin Disease In Vivo
- (2010) Malgorzata Romanowska et al. PLoS One
- Macrophage Dysfunction Impairs Resolution of Inflammation in the Wounds of Diabetic Mice
- (2010) Savita Khanna et al. PLoS One
- Selective and Specific Macrophage Ablation Is Detrimental to Wound Healing in Mice
- (2009) Rita Mirza et al. AMERICAN JOURNAL OF PATHOLOGY
- Efficacy and Safety of Combination Acitretin and Pioglitazone Therapy in Patients With Moderate to Severe Chronic Plaque-Type Psoriasis
- (2009) Rajan Mittal et al. ARCHIVES OF DERMATOLOGY
- Cytoplasmic mislocalization of the orphan nuclear receptor Nurr1 is a prognostic factor in bladder cancer
- (2009) Teruo Inamoto et al. CANCER
- Mast cells in atopic dermatitis
- (2009) Toshiaki Kawakami et al. CURRENT OPINION IN IMMUNOLOGY
- Activators of PPARs and LXR decrease the adverse effects of exogenous glucocorticoids on the epidermis
- (2009) Marianne Demerjian et al. EXPERIMENTAL DERMATOLOGY
- Molecular genetics of human pigmentation diversity
- (2009) R. A. Sturm HUMAN MOLECULAR GENETICS
- Activation of peroxisome proliferator-activated receptor gamma suppresses mast cell maturation involved in allergic diseases
- (2008) M. Tachibana et al. ALLERGY
- A Retrospective Case Series Review of the Peroxisome Proliferator-Activated Receptor Ligand Rosiglitazone in the Treatment of Atopic Dermatitis
- (2008) Ramona Behshad et al. ARCHIVES OF DERMATOLOGY
- Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors
- (2008) Cynthia Hong et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- The skin: an indispensable barrier
- (2008) Ehrhardt Proksch et al. EXPERIMENTAL DERMATOLOGY
- PPARγ agonists attenuate proliferation and modulate Wnt/β-catenin signalling in melanoma cells
- (2008) Aaron G. Smith et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Melanocortin-1 Receptor Signaling Markedly Induces the Expression of the NR4A Nuclear Receptor Subgroup in Melanocytic Cells
- (2008) Aaron G. Smith et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Systemic PPARγ Ligation Inhibits Allergic Immune Response in the Skin
- (2008) Anja Dahten et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Topical Peroxisome Proliferator Activated Receptor Activators Accelerate Postnatal Stratum Corneum Acidification
- (2008) Joachim W. Fluhr et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- 1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth
- (2008) T. Inamoto et al. MOLECULAR CANCER THERAPEUTICS
- Liver X Receptor Is a Therapeutic Target for Photoaging and Chronological Skin Aging
- (2008) Ken C. N. Chang et al. MOLECULAR ENDOCRINOLOGY
- Deficiency of PPARβ/δ in the Epidermis Results in Defective Cutaneous Permeability Barrier Homeostasis and Increased Inflammation
- (2007) Mao-Qiang Man et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Increased Expression of the Orphan Nuclear Receptor NURR1 in Psoriasis and Modulation following TNF-α Inhibition
- (2007) Marina O'Kane et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now