Critical role of Myc activation in mouse hepatocarcinogenesis induced by the activation of AKT and RAS pathways

Cytochrome P450 1A2 Metabolizes 17β-Estradiol to Suppress Hepatocellular Carcinoma

(2016) Jianwai Ren et al.   PLoS One

Impact of MYC in regulation of tumor cell metabolism

(2015) Therese Wahlström et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A pro-tumorigenic function of S100A8/A9 in carcinogen-induced hepatocellular carcinoma

(2015) Aurora De Ponti et al.   CANCER LETTERS

Differential reactivation of fetal/neonatal genes in mouse liver tumors induced in cirrhotic and non-cirrhotic conditions

(2015) Xi Chen et al.   CANCER SCIENCE

Genetic Landscape and Biomarkers of Hepatocellular Carcinoma

(2015) Jessica Zucman-Rossi et al.   GASTROENTEROLOGY

KrasG12D induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells

(2015) S Diersch et al.   ONCOGENE

MYC, Metabolism, and Cancer

(2015) Z. E. Stine et al.   Cancer Discovery

Bioinformatics analysis of the serine and glycine pathway in cancer cells

(2015) Alexey Antonov et al.   Oncotarget

MYC Activates Stem-like Cell Potential in Hepatocarcinoma by a p53-Dependent Mechanism

(2014) H. Akita et al.   CANCER RESEARCH

Targeting RNA polymerase I to treat MYC-driven cancer

(2014) G Poortinga et al.   ONCOGENE

Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice

(2013) L. Soucek et al.   GENES & DEVELOPMENT

Role of Myc in hepatocellular proliferation and hepatocarcinogenesis

(2013) Aijuan Qu et al.   JOURNAL OF HEPATOLOGY

The Oncogene eIF4E: Using Biochemical Insights to Target Cancer

(2013) Martin Carroll et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Regulation of Glucose Homeostasis and Lipid Metabolism by PPP1R3G-mediated Hepatic Glycogenesis

(2013) Yongxian Zhang et al.   MOLECULAR ENDOCRINOLOGY

MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells

(2013) H. Zirath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogene-specific formation of chemoresistant murine hepatic cancer stem cells

(2012) Edward Kai-Hua Chow et al.   HEPATOLOGY

Phosphorylation Regulates c-Myc's Oncogenic Activity in the Mammary Gland

(2011) X. Wang et al.   CANCER RESEARCH

AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2,

(2011) Coral Ho et al.   HEPATOLOGY

Minimal cooperation between mutant Hras and c-myc or TGFα in the regulation of mouse hepatocyte growth or transformation in vivo

(2011) Timothy J. Stein et al.   LIVER INTERNATIONAL

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

(2011) Tae-Won Kang et al.   NATURE

Increased Lipogenesis, Induced by AKT-mTORC1-RPS6 Signaling, Promotes Development of Human Hepatocellular Carcinoma

(2010) Diego F. Calvisi et al.   GASTROENTEROLOGY

Central Role of c-Myc during Malignant Conversion in Human Hepatocarcinogenesis

(2009) P. Kaposi-Novak et al.   CANCER RESEARCH

Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle

(2009) Esther Castellano et al.   GENOME BIOLOGY

Distinct Thresholds Govern Myc's Biological Output In Vivo

(2008) Daniel J. Murphy et al.   CANCER CELL

Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1

(2008) J. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA