VEGFA links self-renewal and metastasis by inducing Sox2 to repress miR-452, driving Slug
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
VEGFA links self-renewal and metastasis by inducing Sox2 to repress miR-452, driving Slug
Authors
Keywords
-
Journal
ONCOGENE
Volume 36, Issue 36, Pages 5199-5211
Publisher
Springer Nature
Online
2017-05-15
DOI
10.1038/onc.2017.4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b–Mediated Malignant Progression
- (2016) Manuel Picon-Ruiz et al. CANCER RESEARCH
- Intratumoral Heterogeneity in a Trp53-Null Mouse Model of Human Breast Cancer
- (2015) M. Zhang et al. Cancer Discovery
- Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures
- (2014) Katherine Drews-Elger et al. BREAST CANCER RESEARCH AND TREATMENT
- CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis
- (2014) Matilde Todaro et al. Cell Stem Cell
- VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2
- (2014) D Zhao et al. ONCOGENE
- A meta-analysis of gene expression-based biomarkers predicting outcome after tamoxifen treatment in breast cancer
- (2013) Zsuzsanna Mihály et al. BREAST CANCER RESEARCH AND TREATMENT
- PI3K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy
- (2013) Seth A. Wander et al. BREAST CANCER RESEARCH AND TREATMENT
- Protein Kinase C α Is a Central Signaling Node and Therapeutic Target for Breast Cancer Stem Cells
- (2013) Wai Leong Tam et al. CANCER CELL
- Downregulation of miR-452 Promotes Stem-Like Traits and Tumorigenicity of Gliomas
- (2013) L. Liu et al. CLINICAL CANCER RESEARCH
- GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation
- (2013) Hira Lal Goel et al. EMBO Molecular Medicine
- Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses
- (2013) Diana J. Azzam et al. EMBO Molecular Medicine
- The shaping and functional consequences of the microRNA landscape in breast cancer
- (2013) Heidi Dvinge et al. NATURE
- Control of metastatic progression by microRNA regulatory networks
- (2013) Nora Pencheva et al. NATURE CELL BIOLOGY
- MicroRNAs regulate both epithelial-to-mesenchymal transition and cancer stem cells
- (2013) P Ceppi et al. ONCOGENE
- Tumor stromal vascular endothelial growth factor A is predictive of poor outcome in inflammatory breast cancer
- (2012) Hugo Arias-Pulido et al. BMC CANCER
- Loss of SNAIL Regulated miR-128-2 on Chromosome 3p22.3 Targets Multiple Stem Cell Factors to Promote Transformation of Mammary Epithelial Cells
- (2012) P. Qian et al. CANCER RESEARCH
- EMT and Dissemination Precede Pancreatic Tumor Formation
- (2012) Andrew D. Rhim et al. CELL
- MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
- (2012) Marilena V. Iorio et al. EMBO Molecular Medicine
- Autocrine VEGF–VEGFR2–Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth
- (2012) Petra Hamerlik et al. JOURNAL OF EXPERIMENTAL MEDICINE
- MicroRNA-34a Modulates c-Myc Transcriptional Complexes to Suppress Malignancy in Human Prostate Cancer Cells
- (2012) Soichiro Yamamura et al. PLoS One
- Silencing SOX2 Induced Mesenchymal-Epithelial Transition and Its Expression Predicts Liver and Lymph Node Metastasis of CRC Patients
- (2012) Xu Han et al. PLoS One
- Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
- (2012) S. J. Conley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNA-138 suppresses epithelial–mesenchymal transition in squamous cell carcinoma cell lines
- (2011) Xiqiang Liu et al. BIOCHEMICAL JOURNAL
- RecurrenceOnline: an online analysis tool to determine breast cancer recurrence and hormone receptor status using microarray data
- (2011) Balázs Győrffy et al. BREAST CANCER RESEARCH AND TREATMENT
- Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer
- (2011) R Xiang et al. BRITISH JOURNAL OF CANCER
- The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells
- (2011) Simone Brabletz et al. EMBO JOURNAL
- MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer
- (2011) Regalla Kumarswamy et al. INTERNATIONAL JOURNAL OF CANCER
- A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition
- (2011) Nam Hee Kim et al. JOURNAL OF CELL BIOLOGY
- An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
- (2011) Philip A. Gregory et al. MOLECULAR BIOLOGY OF THE CELL
- A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours
- (2011) Benjamin Beck et al. NATURE
- Interactions between cancer stem cells and their niche govern metastatic colonization
- (2011) Ilaria Malanchi et al. NATURE
- Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes
- (2011) Erik Engelen et al. NATURE GENETICS
- The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
- (2011) Can Liu et al. NATURE MEDICINE
- Sox2 expression in breast tumours and activation in breast cancer stem cells
- (2011) O Leis et al. ONCOGENE
- miRNA-mRNA Integrated Analysis Reveals Roles for miRNAs in Primary Breast Tumors
- (2011) Espen Enerly et al. PLoS One
- Bevacizumab in the Treatment of Metastatic Breast Cancer: Friend or Foe?
- (2011) Alberto J. Montero et al. Current Oncology Reports
- Autocrine VEGF Signaling Synergizes with EGFR in Tumor Cells to Promote Epithelial Cancer Development
- (2010) Beate M. Lichtenberger et al. CELL
- Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression
- (2010) Douglas S. Micalizzi et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- The VEGF family in cancer and antibody-based strategies for their inhibition
- (2010) Laura A. Sullivan et al. mAbs
- Vascular Endothelial Growth Factor: Much More than an Angiogenesis Factor
- (2010) Donald R. Senger MOLECULAR BIOLOGY OF THE CELL
- Targeting cancer stem cells by inhibiting Wnt, Notch and Hedgehog pathways
- (2010) Naoko Takebe et al. Nature Reviews Clinical Oncology
- ChIP-seq and Functional Analysis of the SOX2 Gene in Colorectal Cancers
- (2010) Xuefeng Fang et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- MicroRNAs in Cancer
- (2009) Ramiro Garzon et al. Annual Review of Medicine
- Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis
- (2009) John M.L. Ebos et al. CANCER CELL
- Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
- (2009) Marta Pàez-Ribes et al. CANCER CELL
- Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
- (2009) Yohei Shimono et al. CELL
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer
- (2009) E. Charafe-Jauffret et al. CLINICAL CANCER RESEARCH
- VEGF elicits epithelial-mesenchymal transition (EMT) in prostate intraepithelial neoplasia (PIN)-like cells via an autocrine loop
- (2009) Oscar Gonzalez-Moreno et al. EXPERIMENTAL CELL RESEARCH
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
- (2009) Ulrich Wellner et al. NATURE CELL BIOLOGY
- Cancer stem cells: mirage or reality?
- (2009) Piyush B Gupta et al. NATURE MEDICINE
- RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility
- (2009) M. D. Larrea et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
- (2008) T. T. Onder et al. CANCER RESEARCH
- Targeting of the Bmi-1 Oncogene/Stem Cell Renewal Factor by MicroRNA-128 Inhibits Glioma Proliferation and Self-Renewal
- (2008) J. Godlewski et al. CANCER RESEARCH
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
- (2008) Ulrike Burk et al. EMBO REPORTS
- The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
- (2008) S.-M. Park et al. GENES & DEVELOPMENT
- The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2
- (2008) Manav Korpal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endogenous human microRNAs that suppress breast cancer metastasis
- (2008) Sohail F. Tavazoie et al. NATURE
- The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
- (2008) Philip A. Gregory et al. NATURE CELL BIOLOGY
- An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors
- (2008) Ittai Ben-Porath et al. NATURE GENETICS
- Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition
- (2008) Anne-Pierre Morel et al. PLoS One
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now