A slow-cycling subpopulation of melanoma cells with highly invasive properties

Prognostic Significance of CDCP1 Expression in Colorectal Cancer and Effect of Its Inhibition on Invasion and Migration

(2015) Chiang-Ting Chou et al.   ANNALS OF SURGICAL ONCOLOGY

Genomic Classification of Cutaneous Melanoma

(2015) Rehan Akbani et al.   CELL

A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis

(2015) Elvin Wagenblast et al.   NATURE

Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas

(2015) Michael Krauthammer et al.   NATURE GENETICS

The Genetic Evolution of Melanoma from Precursor Lesions

(2015) A. Hunter Shain et al.   NEW ENGLAND JOURNAL OF MEDICINE

CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases

(2015) C Leroy et al.   ONCOGENE

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

(2015) E. M. Van Allen et al.   SCIENCE

Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma

(2015) Jonathan J. Lee et al.   Oncotarget

Serpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma

(2015) Catherine Vaillant et al.   PLoS One

Protease Nexin-1 affects the migration and invasion of C6 glioma cells through the regulation of urokinase Plasminogen Activator and Matrix Metalloproteinase-9/2

(2014) Valentina Pagliara et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ABCB5 Maintains Melanoma-Initiating Cells through a Proinflammatory Cytokine Signaling Circuit

(2014) B. J. Wilson et al.   CANCER RESEARCH

Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis

(2014) Manuel Valiente et al.   CELL

Transient TNF regulates the self-renewing capacity of stem-like label-retaining cells in sphere and skin equivalent models of melanoma

(2014) Pauline Ostyn et al.   Cell Communication and Signaling

Prognostic significance of SERPINE2 in gastric cancer and its biological function in SGC7901 cells

(2014) Kun Wang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Comprehensive Comparative and Semiquantitative Proteome of a Very Low Number of Native and Matched Epstein–Barr-Virus-Transformed B Lymphocytes Infiltrating Human Melanoma

(2014) Margarita Maurer et al.   JOURNAL OF PROTEOME RESEARCH

Wnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells

(2014) Marie R. Webster et al.   Pigment Cell & Melanoma Research

A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway Inhibitors

(2014) D. J. Konieczkowski et al.   Cancer Discovery

Heterogeneous Tumor Subpopulations Cooperate to Drive Invasion

(2014) Anna Chapman et al.   Cell Reports

Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells

(2013) Alexander Roesch et al.   CANCER CELL

Late Recurrence in Melanoma: Clinical Implications of Lost Dormancy

(2013) Mark B. Faries et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

A melanocyte lineage program confers resistance to MAP kinase pathway inhibition

(2013) Cory M. Johannessen et al.   NATURE

miR-194 suppresses metastasis of non-small cell lung cancer through regulating expression of BMP1 and p27kip1

(2013) X Wu et al.   ONCOGENE

Three monoclonal antibodies against the serpin protease nexin-1 prevent protease translocation

(2013) T. M. Kousted et al.   THROMBOSIS AND HAEMOSTASIS

MAP Kinase Pathway Alterations in BRAF-Mutant Melanoma Patients with Acquired Resistance to Combined RAF/MEK Inhibition

(2013) N. Wagle et al.   Cancer Discovery

The Genetic Landscape of Clinical Resistance to RAF Inhibition in Metastatic Melanoma

(2013) E. M. Van Allen et al.   Cancer Discovery

Emerging role of serpinE2/protease nexin-1 in hemostasis and vascular biology

(2012) M.-C. Bouton et al.   BLOOD

A Landscape of Driver Mutations in Melanoma

(2012) Eran Hodis et al.   CELL

Differential mechanisms of tumor progression in clones from a single heterogeneous human melanoma

(2012) Walburga Croteau et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Combining Filter-Aided Sample Preparation and Pseudoshotgun Technology To Profile the Proteome of a Low Number of Early Passage Human Melanoma Cells

(2012) Margarita Maurer et al.   JOURNAL OF PROTEOME RESEARCH

General Statistical Modeling of Data from Protein Relative Expression Isobaric Tags

(2011) Florian P. Breitwieser et al.   JOURNAL OF PROTEOME RESEARCH

Matrix Metalloproteinase-9 Regulates Tumor Cell Invasion through Cleavage of Protease Nexin-1

(2010) D. Xu et al.   CANCER RESEARCH

A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth

(2010) Alexander Roesch et al.   CELL

Early tumor dissemination, but late metastasis: insights into tumor dormancy

(2010) Martin Röcken   JOURNAL OF CLINICAL INVESTIGATION

The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesis

(2010) Sébastien Bergeron et al.   Molecular Cancer

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

(2010) Alexander D. Boiko et al.   NATURE

A Distinct Slow-Cycling Cancer Stem-like Subpopulation of Pancreatic Adenocarcinoma Cells is maintained in Vivo

(2010) Jennifer L. Dembinski et al.   Cancers

SERPINE2 is a possible candidate promotor for lymph node metastasis in testicular cancer

(2009) Akira Nagahara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis

(2009) Joanna Selzer-Plon et al.   BMC CANCER

The Serine Protease Inhibitor Protease Nexin-1 Controls Mammary Cancer Metastasis through LRP-1-Mediated MMP-9 Expression

(2009) B. Fayard et al.   CANCER RESEARCH

Plasminogen activator inhibitors regulate cell adhesion through a uPAR-dependent mechanism

(2009) Ralf-Peter Czekay et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Combination of FASP and StageTip-Based Fractionation Allows In-Depth Analysis of the Hippocampal Membrane Proteome

(2009) Jacek R. Wiśniewski et al.   JOURNAL OF PROTEOME RESEARCH

Establishment of an experimental human lung adenocarcinoma cell line SPC-A-1BM with high bone metastases potency by 99mTc-MDP bone scintigraphy

(2009) Shunfang Yang et al.   NUCLEAR MEDICINE AND BIOLOGY

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS

Overexpression of protease nexin-1 mRNA and protein in oral squamous cell carcinomas

(2007) Shan Gao et al.   ORAL ONCOLOGY