Infiltrating mast cells promote renal cell carcinoma angiogenesis by modulating PI3K→AKT→GSK3β→AM signaling

Renal cell carcinoma

(2017) Paul Cairns   Cancer Biomarkers

Mast cells as therapeutic target in cancer

(2016) Domenico Ribatti   EUROPEAN JOURNAL OF PHARMACOLOGY

Activation of KIT modulates the function of tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) in mast cells

(2015) A. Förster et al.   ALLERGY

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Anti-androgen enzalutamide enhances prostate cancer neuroendocrine (NE) differentiation via altering the infiltrated mast cells → androgen receptor (AR) → miRNA32 signals

(2015) Qiang Dang et al.   Molecular Oncology

Natural inhibitors of PI3K/AKT signaling in breast cancer: Emphasis on newly-discovered molecular mechanisms of action

(2015) Yaghoub Safdari et al.   PHARMACOLOGICAL RESEARCH

Infiltrating mast cells enhance prostate cancer invasion via altering LncRNA-HOTAIR/PRC2-androgen receptor (AR)-MMP9 signals and increased stem/progenitor cell population

(2015) Lei Li et al.   Oncotarget

Resistance to Antiangiogenic Therapy Is Associated with an Immunosuppressive Tumor Microenvironment in Metastatic Renal Cell Carcinoma

(2015) X.-D. Liu et al.   Cancer Immunology Research

Mammalian Target of Rapamycin Inhibitors Resistance Mechanisms in Clear Cell Renal Cell Carcinoma

(2014) Anna Kornakiewicz et al.   Current Signal Transduction Therapy

Mast cells protect from skin tumor development and limit tumor growth during cutaneousde novocarcinogenesis in a Kit-dependent mouse model

(2014) Frank Siebenhaar et al.   EXPERIMENTAL DERMATOLOGY

Molecular analysis of sunitinib resistant renal cell carcinoma cells after sequential treatment with RAD001 (everolimus) or sorafenib

(2014) Eva Juengel et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Human Airway Smooth Muscle Promotes Human Lung Mast Cell Survival, Proliferation, and Constitutive Activation: Cooperative Roles for CADM1, Stem Cell Factor, and IL-6

(2014) F. Hollins et al.   JOURNAL OF IMMUNOLOGY

Mast Cells in Abdominal Aortic Aneurysms

(2013) Guo-Ping Shi et al.   Current Vascular Pharmacology

The VHL/HIF axis in clear cell renal carcinoma

(2012) Chuan Shen et al.   SEMINARS IN CANCER BIOLOGY

High density of tryptase-positive mast cells in patients with renal cell carcinoma on hemodialysis: correlation with expression of stem cell factor and protease activated receptor-2

(2011) Shin-ichi Watanabe et al.   HUMAN PATHOLOGY

Resistance of Renal Cell Carcinoma to Sorafenib Is Mediated by Potentially Reversible Gene Expression

(2011) Liang Zhang et al.   PLoS One

Mast cells, angiogenesis, and tumour growth

(2010) Domenico Ribatti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Adrenomedullin as a therapeutic target in angiogenesis

(2010) Jean-Laurent Deville et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Expression and role of adrenomedullin in renal tumors and value of its mRNA levels as prognostic factor in clear-cell renal carcinoma

(2009) Jean-Laurent Deville et al.   INTERNATIONAL JOURNAL OF CANCER

Angiogenesis in renal cell carcinoma: The role of tumor-associated macrophages

(2009) Hiroshi Toge et al.   INTERNATIONAL JOURNAL OF UROLOGY

The lack of correlation between mast cells and microvessel density with pathologic feature of renal cell carcinoma

(2009) Mohammad Ghassem Mohseni et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Renal cell carcinoma

(2009) Brian I Rini et al.   LANCET

Mast cells and tumour angiogenesis: New insight from experimental carcinogenesis

(2008) Enrico Crivellato et al.   CANCER LETTERS

Mast cells and cancer—No longer just basic science

(2008) Daliah Shoshana Tamar Galinsky et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Protein-tyrosine Phosphatase α Regulates Stem Cell Factor-dependent c-Kit Activation and Migration of Mast Cells

(2008) Lionel A. Samayawardhena et al.   JOURNAL OF BIOLOGICAL CHEMISTRY